823 Results for "

B3

" in MedChemExpress (MCE) Product Catalog:
Products (823)

823 Results for "B3" in MCE Product Catalog:

Cat. No.: HY-B0143S3
CAS No.: 1189954-79-7
Synonyms: Nicotinic acid-13C6; Vitamin B3-13C6
Niacin- 13C6 is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
loading...
    loading...
Cat. No.: HY-P88735A
Synonyms: CER2; CERL2; CKTSF1B3; COCO; CRL2; DANTE; GREM3; SP1

Host:  

Mouse

Application:  

ICC/IF, FC

Reactivity:  

Human

loading...
    loading...
RNA Aptamer Peach I sodium
0 Images
5'-GGAAUCCCUGAAGGAUGUGGGGGAGGGAGAAGGGAUUCC-3', sodium salt
Cat. No.: HY-153850
RNA Aptamer Peach Ⅰ (sodium) has an exceptionally high affinity to TO3-Biotin (TO3-B, red channel, ex: 637 nm, em: 658 nm), and can be used to visualize RNA expression or localization in live cells.
loading...
    loading...
Cat. No.: HY-153851
Research Areas:  

Others

RNA Aptamer Peach Ⅱ (sodium) has an exceptionally high affinity to TO3-Biotin (TO3-B, red channel, ex: 637 nm, em: 658 nm), and can be used to visualize RNA expression or localization in live cells.
loading...
    loading...
Cat. No.: HY-P81426A
Synonyms: SF3B3; KIAA0017; SAP130; Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-N15205
CAS No.: 159278-74-7
Rhinacanthin C is an orally active naphthoquinone ester and P-gp inhibitor (IC50 = 5.20 μM). Rhinacanthin C exerts effects in ameliorating hepatic steatosis, insulin resistance, and inflammation by inhibiting P-gp, BCRP, OATP1B1/1B3, and multiple CYP enzymes, downregulating lipid synthesis-related factors such as ACC and FAS, and upregulating AMPKα phosphorylation and SIRT1. Rhinacanthin C can be used in research on non-alcoholic fatty liver disease, diabetes, abnormal osteolysis, Alzheimer's disease, and inflammation [3] .
loading...
    loading...
Cat. No.: HY-P1886
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Kv3, Channel Containing Protein (567-585) corresponds to amino acids 567 to 585 fragment of the Kv3.1b channel containing protein. Kv3 channel protein is expressed by parvalbumin (PV)-containing pallidal neurons .
loading...
    loading...
Cat. No.: HY-N15726
CAS No.: 2414481-40-4
Obtusichromoneside C is a chromone C-glycoside found in the seeds of Cassia obtusifolia. Obtusichromoneside C regulates substance transport by inhibiting substrate uptake of specific transporters (e.g., OAT3, OATP1B3). Obtusichromoneside C is promising for research of drug transport .
loading...
    loading...
Cat. No.: HY-N1992R
CAS No.: 30462-35-2
Synonyms: TF-3 (Standard); ZP10 (Standard)
Theaflavin 3,3'-digallate (Standard) is the analytical standard of Theaflavin 3,3'-digallate. This product is intended for research and analytical applications. Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (Kd=8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1 . Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent .
loading...
    loading...
Cat. No.: HY-P84216
Synonyms: ITGA3; VL3A; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-N3504
CAS No.: 65604-80-0
Ophiopogonin D' is a steroidal saponin and a SIRT1 activator. Ophiopogonin D' can also regulate the activities of transporters OATP1B1 and OATP1B3. Ophiopogonin D' exhibits certain toxicity to tumor cells. Ophiopogonin D' can be used in tumor research [3].
loading...
    loading...
Cat. No.: HY-P82264
Synonyms: ERR 3; ERR gamma 2; ERR3; ERRG2; ERRgamma; ESRRG; NR3B3

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P84216A
Synonyms: ITGA3; VL3A; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-121065
CAS No.: 477603-18-2
Purity:  ≥95.0%
Synonyms: IRC-083065
Target:  

Phosphatase

Research Areas:  

Cancer

BN-82685 is a a quinone-based CDC25 inhibitor with IC50 of 201 nM, 117 nM, 109 nM, 160 nM, 249 nM, for CDC25C, CDC25C-cat, CDC25A, CDC25B2, CDC25B3, respectively. BN-82685 plays an important role in cancer research .
loading...
    loading...
Cat. No.: HY-151207
CAS No.: 2820286-56-2
Target:  

Apoptosis ADC Payloads

Research Areas:  

Cancer

Anticancer agent 81 (Compound 37b3) is an anticancer agent and can induce tumor cell cycle arrest and apoptosis. Anticancer agent 81 can be used as a payload to conjugate with Trastuzumab (HY-P9907) to obtain the antibody–agent conjugate (ADC) T-PBA. T-PBA maintained its mode of target and internalization ability of Trastuzumab .
loading...
    loading...
Cat. No.: HY-15648G
CAS No.: 1797832-71-3
Target:  

Histone Demethylase

Research Areas:  

Cancer

GSK-J1 sodium is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 value of 60 nM towards KDM6B [3].
loading...
    loading...
Cat. No.: HY-117639
CAS No.: 1311136-84-1
Purity:  99.85%
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

AUT1 is a recombinant human Kv3 channel modulator. AUT1 modulates Kv3.1b and Kv3.2a channels in human recombinant with pEC50 values of 5.33 and 5.31 μM, respectively. AUT1 can be used for the research of disorders associated with dysfunction of inhibitory feedback in corticolimbic circuits, such as schizophrenia .
loading...
    loading...
Cat. No.: HY-162935
CAS No.: 1243603-61-3
Target:  

Proton Pump

Research Areas:  

Others

V-ATPase-IN-1 (Compound 3b-03) is a Vacuolar-type H +-ATPases (V-ATPase) inhibitor (IC50 = 194.80 μM) that can effectively target the V-ATPase subunit A (Kd = 0.803 μM). V-ATPase-IN-1 exhibits insecticidal activity against M. separata (LC50 = 2.64 mM) and contributes to research in the development of chemical insecticides .
loading...
    loading...
Cat. No.: HY-N1818
CAS No.: 113122-54-6
Synonyms: 3-Deoxysappanone B
Deoxysappanone B (3-Deoxysappanone B) is a homoisoflavone compound isolated from Caesalpinia sappan L (Lignum Sappan). Deoxysappanone B has anti-neuroinflammatory and neuroprotective effects and inhibits the production of neuroinflammatory mediators by blocking the IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Deoxysappanone B can be used in disease studies of neuritis and inflammation-related neurological damage .
loading...
    loading...
Cat. No.: HY-151388
CAS No.: 254974-70-4
Purity:  98.04%
Target:  

Monoamine Oxidase COMT

Research Areas:  

Neurological Disease

hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor (IC50s: 2.5 μΜ for hMAO-B, 3.84 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-1 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-1 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD) .
loading...
    loading...