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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
823 Results for "
B3
" in MedChemExpress (MCE) Product Catalog:
Products (823)
823 Results for "B3" in MCE Product Catalog:
Cat. No.: HY-P701566
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SF3B3; STAF130; Splicing Factor 3b Subunit 3; SAP 130; SF3b130; Pre-MRNA Splicing Factor SF3b, 130 KDa Subunit; SAP130; Pre-MRNA-Splicing Factor SF3b 130 KDa Subunit; Spliceosome-Associated Protein 130; Splicing Factor 3b, Subunit 3, 130kDa; KIAA0017; Spl
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701567
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SF3B3; STAF130; Splicing Factor 3b Subunit 3; SAP 130; SF3b130; Pre-MRNA Splicing Factor SF3b, 130 KDa Subunit; SAP130; Pre-MRNA-Splicing Factor SF3b 130 KDa Subunit; Spliceosome-Associated Protein 130; Splicing Factor 3b, Subunit 3, 130kDa; KIAA0017; Spl
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-175464
CAS No.: 3091347-92-8
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
NLRP3-IN-82 (Compound 2b) is a NLRP3 inhibitor. NLRP3-IN-82 significantly inhibits lL-1β release in HMDM cells (IC50< 5 nM). NLRP3-IN-82 can be used for neurological diseases like Alzheimer's disease, inflammatory diseases like inflammatory bowel disease and metabolic disorders like obesity research .
Cat. No.: HY-10466S
CAS No.: 1801709-41-0
Synonyms: BMS-790052-d6; EBP 883-d6
Cat. No.: HY-10466S2
Synonyms: BMS-790052-d16; EBP 883-d16
Cat. No.: HY-10465R
CAS No.: 1009119-65-6
Synonyms: BMS-790052 dihydrochloride (Standard); EBP 883 dihydrochloride (Standard)
Target:
Research Areas:
Daclatasvir (dihydrochloride) (Standard) is the analytical standard of Daclatasvir (dihydrochloride). This product is intended for research and analytical applications. Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also an organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively [3].
Cat. No.: HY-10466R
CAS No.: 1009119-64-5
Synonyms: BMS-790052 (Standard); EBP 883 (Standard)
Target:
Research Areas:
Daclatasvir (Standard) is the analytical standard of Daclatasvir. This product is intended for research and analytical applications. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively [3].
Cat. No.: HY-112776
CAS No.: 396073-89-5
Target:
Research Areas:
BN82002 is a potent, selective and irreversible inhibitor of CDC25 phosphatase family. BN82002 inhibits CDC25A, CDC25B2, CDC25B3, CDC25C CDC25A, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 µM, respectively. BN82002 displays ~20-fold greater selectivity over CD45 tyrosine phosphatase .
Cat. No.: HY-143487
CAS No.: 2715225-58-2
Antimalarial agent 12 (compound R-3b) is a potent antimalarial agent. Antimalarial agent 12 shows growth inhibition on P. falciparum Dd2 Strain (EC50=155 nM), 3D7 strain (EC50=136 nM). Antimalarial agent 12 has CC50 values of 10,000 to 50,000 nM for HEK-293 and hPHep cell lines. Antimalarial agent 12 has a MIC of >250,000 nM for Escherichia coli .
Cat. No.: HY-179695
Target:
Research Areas:
Microtubule destabilizing agent-3, a B32B3 (HY-12240) analog, is a microtubule destabilizing agent. Microtubule destabilizing agent-3 exerts its antimyeloma phenotypes by destabilizing microtubules and promoting mitotic arrest, leading to cell death. Microtubule destabilizing agent-3 induces G2/M phase arrest and caspase-dependent apoptosis. Microtubule destabilizing agent-3 can be used for the research of multiple myeloma .
Cat. No.: HY-15648I
CAS No.: 2108665-15-0
Target:
Research Areas:
GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A .
Cat. No.: HY-W016415
CAS No.: 612-37-3
Category:
Target:
Cat. No.: HY-163746
Target:
Research Areas:
BuChE-IN-11 (Compound 3b-1) is an selective BuChE inhibitor with an IC50 of 0.44 μM for hBuChE. BuChE-IN-11 has high blood-brain barrier permeability and exhibits strong antioxidant activity due to its free radical scavenging properties. BuChE-IN-11 interacts with the choline binding site, acetyl binding site, and peripheral anionic site, exhibiting submicromolar BuChE inhibitory activity and preventing β-amyloid (Aβ) self-aggregation. BuChE-IN-11 holds promise for research in the field of Alzheimer's disease .
Cat. No.: HY-P3252AS
Research Areas:
Cat. No.: HY-P84999
Synonyms: B3GAT1; GLCATP; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Beta-1; 3-glucuronyltransferase 1; Glucuronosyltransferase P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1; 3-glucuronyltransferase; GlcUAT-P; CD57 nanobody;
Cat. No.: HY-137936
CAS No.: 83058-94-0
Target:
Research Areas:
Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity. It is active against S. aureus, B. subtilis, and M. roseus (MICs=25, 50, and 25 μg/mL, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells.2 In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
