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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
97 Results for "
complement factor
" in MedChemExpress (MCE) Product Catalog:
Products (97)
97 Results for "complement factor" in MCE Product Catalog:
Cat. No.: HY-127105B
CAS No.: 1644670-38-1
Synonyms: LNP023 TFA
Target:
Research Areas:
Iptacopan (LNP023) TFA is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan TFA exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan TFA can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G) .
Cat. No.: HY-P991022
CAS No.: 2842046-67-5
Synonyms: NM8074
Target:
Research Areas:
Cat. No.: HY-P72691
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFHR3; complement factor H-Related Protein 3; Prev. CFHL3; complement factor H-Related 3, Isoform CRA_c; DOWN16; complement factor H-Related 3; FHR-3; H factor-Like 4; FHR3; CFHR3 Protein; HLF4; complement factor H Related 3; H factor-Like Protein 3
Species:
Human
Source:
HEK293
Cat. No.: HY-P70055
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFHR1; complement factor H-Related 1 Pseudogene; Prev. CFHL1P; H factor (complement)-Like 1; Prev. CFHR1P; H factor (complement)-Like 2; Prev. CFHL1; H factor-Like Protein 1; Prev. HFL1; H-factor-Like 1; Prev. HFL2; FHL-1; FHR1; FHR-1; CFHL; H36; H36-1; C
Species:
Human
Source:
HEK293
Cat. No.: HY-P80577A
Synonyms: AHUS5; ARMD9; ASP; complement C3; complement factor 3; CPAMD1; HEL S 62p
Cat. No.: HY-P991954
Target:
Research Areas:
Cat. No.: HY-181040
CAS No.: 3049710-19-9
Target:
Research Areas:
Factor B-IN-8 (Compound (3R ,4R )-15) is a potent, selective and orally active factor B inhibitor with an IC50 of 10.2 nM. Factor B-IN-8 can effectively inhibit the binding of factor B to C3b and the subsequent formation of C3 convertase (C3bBb). Factor B-IN-8 can inhibit the deposition of membrane attack complex (MAC) mediated by alternativepathway with an IC50 of 59.3 nM. Factor B-IN-8 can reduce the cleavage of factor B protein and decrease the deposition of complement C3d in the glomeruli and renal tubules. Factor B-IN-8 can be used for researches of arthritis and paroxysmal nocturnal hemoglobinuria (PNH) .
Cat. No.: HY-P70102
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFHR5; complement factor H-Related 5; Prev. CFHL5; factor H-Related Protein 5; FHR-5; CFHR5 Protein; FHR5; CFHR5D; complement factor H-Related Protein 5; complement factor H Related 5; factor H Related Protein 5
Species:
Human
Source:
HEK293
Cat. No.: HY-P704969
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VTN; Vitronectin; VN; Serum Spreading factor; Serum-Spreading factor; complement S-Protein; Somatomedin B; S-Protein; V75; Vitronectin (Serum Spreading factor, Somatomedin B, complement S-Protein); Epibolin; VNT
Species:
Human
Source:
HEK293
Cat. No.: HY-P70485G
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VTN; Vitronectin; VN; Serum Spreading factor; Serum-Spreading factor; complement S-Protein; Somatomedin B; S-Protein; V75; Vitronectin (Serum Spreading factor, Somatomedin B, complement S-Protein); Epibolin; VNT
Species:
Human
Source:
HEK293
Cat. No.: HY-P704067
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VTN; Vitronectin; VN; Serum Spreading factor; Serum-Spreading factor; complement S-Protein; Somatomedin B; S-Protein; V75; Vitronectin (Serum Spreading factor, Somatomedin B, complement S-Protein); Epibolin; VNT
Species:
Human
Source:
E. coli
Cat. No.: HY-P75655
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD55; CD55 Molecule, Decay Accelerating factor For complement (Cromer Blood Group); Prev. DAF; Rh Blood Group D Antigen; CROM; CD55 Antigen; CR; CD55 Antigen, Decay Accelerating factor For complement (Cromer Blood Group), Isoform CRA_d; complement Decay-Accelerating factor; Decay Accelerating factor For complement (CD55, Cromer Blood Group System); TC; CHAPLE; CD55 Molecule (Cromer Blood Group); Cromer Blood Group Antigen
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P72721
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD55; CD55 Molecule, Decay Accelerating factor For complement (Cromer Blood Group); Prev. DAF; Rh Blood Group D Antigen; CROM; CD55 Antigen; CR; CD55 Antigen, Decay Accelerating factor For complement (Cromer Blood Group), Isoform CRA_d; complement Decay-A
Species:
Human
Source:
HEK293
Cat. No.: HY-P75394
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD55; CD55 Molecule, Decay Accelerating factor For complement (Cromer Blood Group); Prev. DAF; Rh Blood Group D Antigen; CROM; CD55 Antigen; CR; CD55 Antigen, Decay Accelerating factor For complement (Cromer Blood Group), Isoform CRA_d; complement Decay-A
Species:
Human
Source:
HEK293
Cat. No.: HY-P76241
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD55; CD55 Molecule, Decay Accelerating factor For complement (Cromer Blood Group); Prev. DAF; Rh Blood Group D Antigen; CROM; CD55 Antigen; CR; CD55 Antigen, Decay Accelerating factor For complement (Cromer Blood Group), Isoform CRA_d; complement Decay-A
Species:
Rat
Source:
HEK293
Cat. No.: HY-P77617
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD55; CD55 Molecule, Decay Accelerating factor For complement (Cromer Blood Group); Prev. DAF; Rh Blood Group D Antigen; CROM; CD55 Antigen; CR; CD55 Antigen, Decay Accelerating factor For complement (Cromer Blood Group), Isoform CRA_d; complement Decay-A
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P82695A
Synonyms: CD55; CR; DAF; complement decay-accelerating factor; CD55
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
