396 Results for "

Complement

" in MedChemExpress (MCE) Product Catalog:
Products (396)

396 Results for "Complement" in MCE Product Catalog:

Cat. No.: HY-138281
CAS No.: 1903742-34-6
Purity:  99.33%
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases .
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Cat. No.: HY-P99767
CAS No.: 2210314-30-8
Synonyms: ALXN1007; Lendalizumab

Target:  

Complement System

Research Areas:  

Infection

Olendalizumab (ALXN1007) is a mouse-derived and humanized IgG2-G4-κ antibody, targeting to Complement protein C5a (Ki=60 pM). Olendalizumab targets the complement inflammatory pathway. Moreover, Olendalizumab can be used for research of complement mediated disorder caused by corona virus .
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Cat. No.: HY-177123
CAS No.: 2922808-66-8
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM. Refinicopan inhibits hemolysis of rabbit red blood cells. Refinicopan can be used to study diseases mediated by complement factor D .
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Cat. No.: HY-172239
CAS No.: 2378381-06-5
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Tarvicopan is an inhibitor for complement factor D .
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Cat. No.: HY-177621
CAS No.: 3069641-77-3
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Cevolisiran, a siRNA, is a complement component 3 (C3) synthesis reducer.
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Cat. No.: HY-177621A
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Cevolisiran sodium, a siRNA, is a complement component 3 (C3) synthesis reducer.
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Cat. No.: HY-P2830
CAS No.: 37213-56-2
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

Complement factor D is a serine protease. Complement factor D activates C3 convertase by specifically cleaving complement Factor B. Complement factor D is promising for research of autoimmune diseases (e.g., paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy), age-related macular degeneration, and thrombotic microangiopathies .
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Cat. No.: HY-P2969
CAS No.: 80295-66-5
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) .
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Cat. No.: HY-P990378

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Anti-Complement Factor P/Properdin Antibody is a humanized antibody expressed in CHO, targeting Complement Factor P/Properdin. Anti-Complement Factor P/Properdin Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Complement Factor P/Properdin Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P5528
Target:  

Inhibitory Antibodies

Research Areas:  

Others

2Abz-SLGRKIQIK(Dnp)-NH2 is a biological active peptide. (This peptide is a second complement component (C2), the physiological substrate for the proenzyme Cls, first complement component. The complement system is a central component of host defense but can also contribute to the inflammation seen in pathological conditions. The C1s protease of the C1 complex initiates the host defense pathway. This peptide employs 2Abz/Dnp FRET pair for quantitation of complement enzyme activity.)
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Cat. No.: HY-NP0194B
C1q Protein (rabbit) is a complement protein and is a recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. C1q Protein (rabbit) binds various ligands derived from self, non-self, and altered self and modulate the functions of immune
and non-immune cells. C1q Protein (rabbit) can be used for the research of mutiple disease .
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Cat. No.: HY-177611A
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Agazisiran sodium, a siRNA,is a complement factor B synthesis reducer.
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Cat. No.: HY-P1505
CAS No.: 63555-63-5
Synonyms: Complement 3a (70-77)
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a.
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Cat. No.: HY-P990377

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-Complement Factor B Antibody is a CHO-expressed human antibody that targets Complement Factor B. The Anti-Complement Factor B Antibody carries a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Complement Factor B Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-102034R
CAS No.: 1386455-76-0
Complement factor D-IN-1 (Standard) is the analytical standard of Complement factor D-IN-1 (HY-102034). This product is intended for research and analytical applications. Complement factor D-IN-1 is a potent and selective small-molecule reversible factor d inhibitor, with IC50s of 0.006 and 0.05 μM in FD Thioesterolytic Fluorescent Assay and a MAC Deposition Assay, respectively.
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Cat. No.: HY-P990376

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-Complement C5aR1 Antibody is a human recombinant antibody expressed in CHO cells, targeting C5AR/C5AR1 /C5R1. Anti-Complement C5aR1 Antibody has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 146.4 kDa. The isotype control for Anti-Complement C5aR1 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P74372
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C7; Complement Component C7; Complement C7; Complement Component 7
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P74373
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C6; Complement Component C6; Complement C6; Complement Component 6
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705312
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C9; Complement Component 9; Complement C9; ARMD15; Complement Component C9; C9D
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P74371
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C7; Complement Component C7; Complement C7; Complement Component 7
Species:  
Human
Source:  
HEK293
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