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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
131 Results for "
exacerbations
" in MedChemExpress (MCE) Product Catalog:
Products (131)
131 Results for "exacerbations" in MCE Product Catalog:
Cat. No.: HY-114611
CAS No.: 2011754-00-8
Target:
Research Areas:
BDM44768 is an inhibitior of IDE. BDM44768 exacerbates ER stress-induced IRE1 activation and promotes lipid accumulation in hepatocytes. BDM44768 potentiates activation of the IRE1 pathway in the liver and exacerbates liver lipid accumulation in an acute mice model of ER stress .
Cat. No.: HY-66011R
CAS No.: 186826-86-8
Synonyms: BAY 12-8039 (Standard)
Target:
Moxifloxacin (Hydrochloride) (Standard) is the analytical standard of Moxifloxacin (Hydrochloride). This product is intended for research and analytical applications. Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia .
Cat. No.: HY-127022
CAS No.: 52646-92-1
Synonyms: Daturamine; α-Hydroxyscopolamine
Cat. No.: HY-127022A
CAS No.: 76822-34-9
Synonyms: Daturamine hydrobromide; α-Hydroxyscopolamine hydrobromide
Research Areas:
Anisodine (Daturamine) hydrobromide is a neuroprotective compound that reduces exacerbated M1, M2, M4, and M5 receptor expression in brain tissues under hypoxia/reoxygenation conditions. Anisodine hydrobromide inhibits calcium ion influx and reactive oxygen species (ROS)levels. Anisodine hydrobromide leads to decreased aspartate levels during hypoxia .
Cat. No.: HY-14644B
CAS No.: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
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Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
Cat. No.: HY-W540188
CAS No.: 21085-60-9
Synonyms: Ketomalonic acid calcium; Mesoxalic acid calcium; Oxomalonic acid calcium
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Calcium mesoxalate (Ketomalonic acid calcium) is an orally active antidiabetic agent. Calcium mesoxalate increases pancreatic insulin content. Calcium mesoxalate reduces dietary hyperglycemia. Calcium mesoxalate inhibits Epinephrine-induced hyperglycemia in rabbits and exacerbates Alloxan (HY-116823)-induced hypoglycemic convulsions. Calcium mesoxalate exerts no antidiabetic effect in pancreatectomized dogs and fails to reduce the susceptibility of rabbits to Alloxan-induced diabetes. Calcium mesoxalate can be used in diabetes-related research .
Cat. No.: HY-17452AR
CAS No.: 117467-28-4
Synonyms: Cefditoren pivoxyl (Standard); Cefditoren pivaloyloxymethyl ester (Standard); ME 1207 (Standard)
Research Areas:
Cefditoren Pivoxil (Standard) is the analytical standard of Cefditoren Pivoxil. This product is intended for research and analytical applications. Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
Triclosan (Standard) is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
Cat. No.: HY-P990197
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Cat. No.: HY-123630R
CAS No.: 25956-17-6
Synonyms: FD&C RED NO. 40 (Standard); CI 16035 (Standard)
Target:
Fluorescent Dye Interleukin Related 5-HT Receptor IFNAR Reactive Oxygen Species (ROS) Reference Standards
Research Areas:
Allura Red AC (Standard) is an analytical standard of Allura Red AC. This product is intended for research and analytical applications. Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine (5-HT) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety .
Cat. No.: HY-W051612
CAS No.: 16900-57-5
DL-Propargylglycine hydrochloride is an irreversible and selective CSE inhibitor that blocks the biosynthesis of endogenous hydrogen sulfide. DL-Propargylglycine hydrochloride induces ROS and TGF-β1 expression. DL-Propargylglycine hydrochloride downregulates carotid ACE2 and Ang-(1-7), and elevates Ang II. DL-Propargylglycine hydrochloride upregulates ICAM-1/LFA-1, exacerbating Aspirin (HY-14654)-induced gastric mucosal injury. DL-Propargylglycine hydrochloride is used in research on diabetes-induced liver injury, diabetic nephropathy, atherosclerosis, gastric mucosal injury, hemorrhagic shock, and Streptococcus agalactiae infection .
Cat. No.: HY-P10405
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Decarboxy Moxifloxacin (compound 8) is a decarboxylated compound of Moxifloxacin. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia .
Cat. No.: HY-W741028
Target:
Research Areas:
Moxifloxacin N-sulfate disodium is an anionic sulfonate derivative of Moxifloxacin (HY-66011A). Moxifloxacin is an 8-methoxyquinolone antibacterial antibiotic used in the research of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and infectious pneumonia .
Cat. No.: HY-W748099
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Tetranor-Misoprostol is a derivative of Moxifloxacin (HY-66011A) and the active metabolite of a prostaglandin E1 analog. Moxifloxacin is an 8-methoxyquinolone antibacterial antibiotic used in the research of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and infectious pneumonia .
Cat. No.: HY-66011S
CAS No.: 1217802-65-7
Synonyms: rac cis-BAY 12-8039-d4
Cat. No.: HY-66011AS6
Synonyms: BAY 12-8039-d4
Cat. No.: HY-66011AS5
CAS No.: 1092356-43-8
Synonyms: BAY 12-8039-d5 free base
Cat. No.: HY-66011AS3
CAS No.: 1246816-75-0
Synonyms: BAY 12-8039-d3-1
Cat. No.: HY-B1810S
CAS No.: 1325559-14-5
Synonyms: C-78-d9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
