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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
96 Results for "
positron
" in MedChemExpress (MCE) Product Catalog:
Products (96)
96 Results for "positron" in MCE Product Catalog:
Cat. No.: HY-156102
CAS No.: 3056613-20-5
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c-ABL-IN-5 is a selective c-Abl inhibitor with neuroprotective effects. c-ABL-IN-5 has blood-brain barrier penetrability, metabolic stability and good pharmacokinetic properties. When c-ABL-IN-5 is labeled with [18F] (compound [18F]3), it can be used as a tracer to evaluate disease-modifying efficacy by complementary positron emission tomography (PET). c-ABL-IN-5 can be used in the study of neurodegenerative diseases such as Parkinson's disease (PD) .
Cat. No.: HY-114253
CAS No.: 2130982-18-0
ODS-2004436 is a small molecule radiotracer that uses positron emission tomography (PET) imaging to measure the activity of the epidermal growth factor receptor (EGFR) in tumors. ODS-2004436 labeled with the radioactive isotope fluorine-18 shows significantly higher uptake in the xenograft models of lung cancer with EGFR mutations compared to the wild-type models, and could be used to distinguish the mutation status. ODS-2004436 can be used to identify EGFR-positive tumors and predict their response to certain reagent treatments, especially for non-small cell lung cancer (NSCLC) .
Cat. No.: HY-175367
CAS No.: 2183338-59-0
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H3R antagonist 6 (Compounds 3) (H3-2406) is a Histamine receptor 3 (H3R) antagonist with an IC50 of 5.6 nM. H3R antagonist 6 labeled with 18F has high radiochemical yield, molar activity and moderate brain uptake, but with an off-target binding to the Sigma-1 receptor. H3R antagonist 6 can be used as a PET radioligand for positron emission tomography imaging for central nervous system (CNS) disorders research .
Cat. No.: HY-121659
CAS No.: 564482-79-7
DCFBC is a prostate-specific membrane antigen (PSMA) inhibitor that can be used for small animal positron emission tomography (PET) imaging. DCFBC labeled with F 18 ([18F]DCFBC) can images in severe combined immunodeficient mice. [18F]DCFBC uptake is higher in PIP tumors, but almost absent in FLU tumors. [18F]DCFBC uptake is also high in the kidney and bladder, but the radioactivity washout time is shorter than that in PIP tumors. Indicating that [18F]DCFBC can specifically localize to PSMA+ expressing tumors and is applicable to the study of prostate cancer .
Cat. No.: HY-P10744
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Cat. No.: HY-141637S
CAS No.: 478518-95-5
Cat. No.: HY-141637S1
Cat. No.: HY-171416
CAS No.: 1955527-32-8
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LCD36, a derivative of nicotinamide adenine dinucleotide (NAD), can be used for synthesis of PARP-1 tracers for positron emission tomography (PET) imaging of the enzyme activity of PARP-1 .
Cat. No.: HY-160607A
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MMA-NODAGA TFA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA TFA can be used to conjugate with exosome and 64Cu in image with positron emission tomography (PET) .
Cat. No.: HY-167899
CAS No.: 1835647-08-9
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PXT-012253 is a positron emission tomography (PET) ligand for mGluR4, as it binds to an allosteric site on mGluR4. PXT-012253 can be utilized in researches related to Parkinson's disease and levodopa-induced dyskinesia .
Cat. No.: HY-402737
CAS No.: 1121932-61-3
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FTC-146 precursor (Compound s6) is a drug intermediate that can be used to prepare σ-1 receptor positron emission tomography tracers ([¹⁸F]FTC-146) .
Cat. No.: HY-178221
CAS No.: 1206475-68-4
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(S)-P-SCN-BN-NOTA is a bifunctional chelating agent that can covalently link the radioactive nuclide ⁶⁴Cu with the ZPDGFRβ affibody, thereby constructing a molecular probe [⁶⁴Cu]Cu-NOTA-ZPDGFRβ for positron emission tomography .
Cat. No.: HY-181580
FAP Ligand 3 is a FAP ligand with a Ki value of 0.092 nM. FAP Ligand 3 acts as a tumor-retaining agent and serves as a FAP-targeted positron emission tomography (PET) tracer for tumor imaging. FAP Ligand 3 is applicable to studies related to glioma .
Cat. No.: HY-14889
CAS No.: 222727-43-7
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Fluciclovine is an amino acid analogue that can enter cells by targeting the amino acid transporters on the cell surface (mainly ASCT2 and LAT1). After being labeled with ¹⁸F, ¹⁸F-fluciclovine can be used as an imaging agent for positron emission tomography (PET) for prostate diagnosis imaging .
Cat. No.: HY-P11835
CAS No.: 3062270-62-3
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Cat. No.: HY-185550
CAS No.: 3033951-95-7
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ACI-19626 precursor (Compound 20) is the precursor of the TDP-43 protein probe ACI-19626 (HY-163575). ACI-19626 is a TDP-43 aggregation inhibitor that can be used in imaging diagnostics such as positron emission tomography (PET) to detect and distinguish related neurodegenerative diseases .
Cat. No.: HY-180344
CAS No.: 863888-33-9
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Flurpiridaz is a positron emission tomography (PET) myocardial perfusion imaging tracer. Flurpiridaz can bind to mitochondrial complex I with high affinity. Flurpiridaz demonstrates high heart uptake in multiple species with clear delineation of perfusion deficits. Flurpiridaz shows rapid uptake in the myocardium. Flurpiridaz can be studied in research on coronary artery disease .
Cat. No.: HY-180347
CAS No.: 1204408-27-4
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HD-800 is a tubulin inhibitor with an IC50 of 4.3 nM and an EC50 for depolymerization of 24 nM. HD-800 can be used to generate a radioactive tracer [11C]HD-800, and [11C]HD-800 can penetrate the blood-brain barrier and be used for positron emission tomography (PET) in various neurological diseases .
Cat. No.: HY-183374
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NYM074 is a carbonic anhydrase IX (CAIX) ligand. NYM074 binds specifically to human CAIX to enable targeted radionuclide delivery. NYM074 supports dual radiolabeling with 68Ga for positron emission tomography (PET) imaging and 177Lu for radionuclide applications. NYM074 can be used for the research of clear cell renal cell carcinoma .
Cat. No.: HY-167898
CAS No.: 955376-42-8
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MeS-IMPY is a ligand of β-amyloid plaques. MeS-IMPY shows a high binding affinity to β-amyloid plaques extracted from Alzheimer's disease (AD) human brains or AD brain homogenates compared to IMPY (Ki=7.93 and 8.95 nM, respectively). [ 11C]MeS-IMPY is a potential radioligand for imaging β-amyloid plaques with positron emission tomography (PET) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
