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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5704 Results for "
solid-state NMR analysis
" in MedChemExpress (MCE) Product Catalog:
Products (5704)
5704 Results for "solid-state NMR analysis" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-D1423
CAS No.: 68654-25-1
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Dibromobimane is a Fluorescent dye and probe that can be used for the detection of intracellular reduced glutathione and the analysis of spatial proximity of closely adjacent cysteine thiol groups. Dibromobimane activates fluorescence through binding to thiol groups; its excitation/emission wavelengths are Ex/Em = 393/477 nm for glutathione detection, and Ex/Em = 385/477 nm for cysteine thiol cross-linking. Dibromobimane uses two equivalent bromomethyl groups to cross-link cysteine thiolates with a distance ranging from 3-6 Å. Dibromobimane can be applied to 96-well microplate-based high-throughput assays for labeling intracellular glutathione, and its fluorescence signal is normalized against nuclear staining results to eliminate the impact of cell density .
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1 Cited Publications
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Bisindolylmaleimide III is a protein kinase C (PKC) inhibitor with IC50 values of 0.26, 5.7, and 6 μM against PKCα, PKCδ, and PKCμ, respectively. Bisindolylmaleimide III also exhibits inhibitory activity against other off-targets, with IC50 values of 0.17, 1, and 2 μM against SLK, adenosine kinase (AK), and CDK2, respectively; its Ki for NQO2 is 16.5 μM. Bisindolylmaleimide III selectively binds to activated Rsk1 following EGF stimulation, and serves as a tool for detecting the activation status of intracellular Rsk1 and PKCα, as well as for functional analysis of SLK. Bisindolylmaleimide III can be used in studies of signal transduction and colorectal cancer .
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1 Cited Publications
Cat. No.: HY-D1668
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1 Cited Publications
Cat. No.: HY-W110883
CAS No.: 3618-43-7
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Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins .
Cat. No.: HY-D0785
CAS No.: 29270-56-2
Synonyms: 4-Fluoro-7-nitrobenzofurazan
Cat. No.: HY-W021005
CAS No.: 189114-61-2
Synonyms: Silver triflimide
Research Areas:
Silver(I) fluoride is a drug intermediate for synthesis of various active compounds. Silver(I) fluoride is a silver(I) complex that can form hydrates in aqueous solutions and in the solid state, enabling its localized application to the tooth decay area for oral health research .
Cat. No.: HY-W017469
CAS No.: 487-68-3
Synonyms: 2,4,6-Trimethylbenzaldehyde
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Cat. No.: HY-W017054
CAS No.: 115-69-5
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2-Amino-2-methyl-1,3-propanediol is a solid-solid phase change material with energy release and heat storage properties. 2-Amino-2-methyl-1,3-propanediol can crystallize from a supercooled solid state, release thermal energy during heating, and store thermal energy in the supercooled solid state. 2-Amino-2-methyl-1,3-propanediol can be used in the production of surfactants, vulcanization accelerators, and as a biological buffer .
Cat. No.: HY-N7541
CAS No.: 656830-24-9
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Cat. No.: HY-W013396
CAS No.: 619-58-9
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4-Iodobenzoic acid is a 4-iodobenzoic acid that crystallizes as a dimer in the monoclinic space group P21/n, with a phase transition center temperature of 230.77 K, and exhibits intermolecular iodine-iodine van der Waals interactions. 4-Iodobenzoic acid can be used in studies of hydrogen bonding, crystal packing and solid-state phase transitions .
Cat. No.: HY-W004547
CAS No.: 18511-69-8
Synonyms: 4,4'-Diamino-2,2'-bipyridine
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
