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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
907 Results for "
Geomyces sp.
" in MedChemExpress (MCE) Product Catalog:
Products (907)
907 Results for "Geomyces sp." in MCE Product Catalog:
Cat. No.: HY-P85854
Synonyms: CLU; APOJ; CLI; KUB1; AAG4; Clusterin; Aging-associated gene 4 protein; Apolipoprotein J; Apo-J; Complement cytolysis inhibitor; CLI; Complement-associated protein SP-40; 40; Ku70-binding protein 1; NA1/NA2; Testosterone-repressed prostate m
Cat. No.: HY-P811990A
Synonyms: SPTB; Spectrin Beta, Erythrocytic; Spectrin Beta Chain, Erythrocytic; Beta-I Spectrin; Erythrocytic Spectrin Beta Chain; Spectrin Beta Chain, Erythrocyte; Spherocytosis, Clinical Type I; Membrane Cytoskeletal Protein; Spectrin Beta Tandil; Sp Beta; HSPTB1; SPTB1; SPH2; EL3; HS2
Cat. No.: HY-P702524
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ST14; Matriptase; Prev. PRSS14; TADG15; MT-SP1; Suppression Of Tumorigenicity 14 (Colon Carcinoma, Matriptase, Epithin); SNC19; Tumor Associated Differentially Expressed Gene 15 Protein; TMPRSS14; Tumor-Associated Differentially-Expressed Gene 15 Protein
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P702523
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ST14; Matriptase; Prev. PRSS14; TADG15; MT-SP1; Suppression Of Tumorigenicity 14 (Colon Carcinoma, Matriptase, Epithin); SNC19; Tumor Associated Differentially Expressed Gene 15 Protein; TMPRSS14; Tumor-Associated Differentially-Expressed Gene 15 Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-155721
CAS No.: 1178895-15-2
Synonyms: 22-4′-Pyridinecarbonyl jorunnamycin A
22-(4′-py)-JA is a semisynthetic derivative of junamycin A (JA) that can be isolated from the Thai blue sponge (Xestospongia sp.). 22-(4′-py)-JA has antimetastatic activity and can inhibit AKT/mTOR/p70S6K signaling. 22-(4′-py)-JA inhibits tumor cell invasion and tube formation in human umbilical vein endothelial cells (HUVEC), downregulates metalloproteinases (MMP-2 and MMP-9), hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF). 22-(4′-py)-JA has potent anticancer activity against non-small cell lung cancer (NSCLC) .
Cat. No.: HY-D0027S1
Synonyms: Coumarin 120-d4; AMC-d4
Cat. No.: HY-W100287
CAS No.: 4532-33-6
Cat. No.: HY-P85921
Synonyms: GDB; Golli MBP; Golli MBP; myelin basic protein; Hemopoietic MBP; HMBPR; HUGO; MBP; MBP_CAVPO; MBP_HUMAN; MGC99675; MLD; Myelin A1 protein; Myelin A1 Protein, basic; Myelin basic protein; Myelin Deficient; Myelin membrane encephalitogenic protein; OTTHUMP00000163776; OTTHUMP00000174387; OTTHUMP00000174388; SHI; Shiverer; SP
Cat. No.: HY-L944
11028 compounds
MCE 18 stands for Medicinal Chemistry Evolution 2018. This metric was established based on structural data of 28,161 patented lead molecules, 1,370 marketed innovative drugs, and nearly 30,000 investigational candidates from preclinical to Phase III stages across 23 major global pharmaceutical companies from 1950 to 2018. After scaffold clustering analysis, a scoring model was constructed by integrating five three dimensional scaffold characteristics, including aromatic rings (AR), non aromatic heterocycles (NAR), chiral centers (CHIRAL), spirocycles (SPIRO), and the sp³ carbon ratio in cyclic and acyclic moieties, enabling quantitative assessment of molecular scaffold novelty and three dimensional complexity.
According to the score distribution of patented molecules, the top 25% of the original patent dataset was defined as the high novelty region. MCE 18 high scoring compounds selected based on this criterion can effectively avoid scaffold patent conflicts and intellectual property risks from the source. Molecules in this range typically feature a high sp³ carbon ratio, abundant chiral centers, spirocycles, and fused heterocycles with prominent three dimensional conformations. Their spatial properties allow precise matching to complex non traditional undruggable target pockets such as PPI interfaces and allosteric sites, making them ideal structural types for early stage screening of First in class drugs.
MCE‑18 Novelty Focused drug‑Like library strictly selects molecules from the aforementioned high scoring range, containing more than 10,000 premium drug like molecules with highly diverse scaffolds and rich 3D diversity. It can be used for high throughput screening of well established targets such as kinases, GPCRs, and proteases, and is especially suitable for hit identification in allosteric modulation, protein–protein interactions, and various undruggable orphan targets, fully supporting early stage drug discovery for cutting edge innovat
Cat. No.: HY-W040129R
CAS No.: 7059-24-7
Category:
Cat. No.: HY-W100287R
CAS No.: 4532-33-6
Cat. No.: HY-P70108
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRSS22; Serine Protease 26; Serine Protease 22; Tryptase Epsilon; BSSP-4; Protease, Serine S1 Family Member 22; Brain-Specific Serine Protease 4; Prosemin; HBSSP-4; PRSS26; SP001LA; BSSP4; Protease, Serine 22
Species:
Human
Source:
HEK293
Cat. No.: HY-P76675
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TLE3; Enhancer Of Split Groucho-Like Protein 3; TLE Family Member 3, Transcriptional Corepressor; Transducin Like Enhancer Of Split 3; ESG3; Transducin-Like Enhancer Protein 3; HsT18976; Transducin-Like Enhancer Of Split 3, Homolog Of Drosophila E(Sp1); K
Species:
Human
Source:
E. coli
Cat. No.: HY-P71604
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TMPRSS4; Channel-Activating Serine Protease 2; Transmembrane Serine Protease 4; Type II Membrane Serine Protease; TMPRSS3; Transmembrane Protease, Serine 4; MT-SP2; Transmembrane Serine Protease 3; Membrane-Type Serine Protease 2; Channel-Activating Prote
Species:
Mouse
Source:
E. coli
Cat. No.: HY-Y0837S
CAS No.: 352438-84-7
Synonyms: (S)-2-Amino-1-propanol-d3; (S)-2-Aminopropanol-d3; (S)-Alaninol-d3
Cat. No.: HY-N20617
CAS No.: 69809-46-7
Cat. No.: HY-P74745
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: MAP2K6; Stress-Activated Protein Kinase Kinase 3; Prev. PRKMK6; SAPK Kinase 3; SAPKK3; SAPKK-3; MEK6; MAPKK 6; MKK6; CRCMSL; MAPKK6; MEK 6; Protein Kinase, Mitogen-Activated, Kinase 6 (MAP Kinase Kinase 6); Mitogen-Activated Protein Kinase Kinase; Dual Sp
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P74746
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP2K6; Stress-Activated Protein Kinase Kinase 3; Prev. PRKMK6; SAPK Kinase 3; SAPKK3; SAPKK-3; MEK6; MAPKK 6; MKK6; CRCMSL; MAPKK6; MEK 6; Protein Kinase, Mitogen-Activated, Kinase 6 (MAP Kinase Kinase 6); Mitogen-Activated Protein Kinase Kinase; Dual Sp
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P700592
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP2K6; Stress-Activated Protein Kinase Kinase 3; Prev. PRKMK6; SAPK Kinase 3; SAPKK3; SAPKK-3; MEK6; MAPKK 6; MKK6; CRCMSL; MAPKK6; MEK 6; Protein Kinase, Mitogen-Activated, Kinase 6 (MAP Kinase Kinase 6); Mitogen-Activated Protein Kinase Kinase; Dual Sp
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P74748
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAP2K6; Stress-Activated Protein Kinase Kinase 3; Prev. PRKMK6; SAPK Kinase 3; SAPKK3; SAPKK-3; MEK6; MAPKK 6; MKK6; CRCMSL; MAPKK6; MEK 6; Protein Kinase, Mitogen-Activated, Kinase 6 (MAP Kinase Kinase 6); Mitogen-Activated Protein Kinase Kinase; Dual Sp
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
