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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
121 Results for "
Ace2
" in MedChemExpress (MCE) Product Catalog:
Products (121)
121 Results for "Ace2" in MCE Product Catalog:
Cat. No.: HY-P11464
Domaines de recherche:
Cat. No.: HY-P5407A
Cat. No.: HY-100450R
CAS No.: 78606-80-1
Domaines de recherche:
BML-111 (Standard) is the analytical standard of BML-111 (HY-100450). This product is intended for research and analytical applications. BML-111, a lipoxin A4 analog, is a lipoxin A4 receptor agonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangiogenic, antitumor and anti-inflammatory properties [2].
Cat. No.: HY-188177
CAS No.: 959582-79-7
MU-UNMC-1 is a SARS-CoV-2 inhibitor. MU-UNMC-1 blocks the binding of the SARS-CoV-2 Spike protein (S protein) to the ACE2 receptor, preventing viral attachment and entry. MU-UNMC-1 inhibits SARS-CoV-2 replication in cell culture. MU-UNMC-1 can be used for research on COVID-19 [2].
Cat. No.: HY-W092987
CAS No.: 99429-64-8
Domaines de recherche:
Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate is a quinoline compound that targets the angiotensin-converting enzyme ACE2 receptor and exhibits anti-SARS-CoV-2 activity. Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate blocks the binding of SARS-CoV-2 to host cells and is used in research on coronavirus disease 2019 (COVID-19) .
Cat. No.: HY-161261
SARS-CoV-2-IN-81 (compound 12e) is a potent AAK1 inhibitor with an IC50 value of 9.38 nM. SARS-CoV-2-IN-81 shows anti-viral property against SARS-CoV-2. SARS-CoV-2-IN-81 attenuates AAK1-induced phosphorylation of AP2M1 threonine 156 and disrupts the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection .
Cat. No.: HY-180129
CAS No.: 308293-08-5
SARS-CoV-2-IN-120 (Compound S22) is a SARS-CoV-2-specific entry inhibitor. SARS-CoV-2-IN-120 binds and trimerizes within the apex cavity of the SARS2 spike trimer. SARS-CoV-2-IN-120 blocks RBD-ACE2 interaction. SARS-CoV-2-IN-120 neutralizes BA.2 and subsequent Omicron variants. SARS-CoV-2-IN-120 inhibits SARS-CoV-2 replication in mice .
Cat. No.: HY-14393S
CAS No.: 132796-52-2
Synonyms: Frangula emodin-d4
Cat. No.: HY-178160
CAS No.: 1581755-42-1
Target:
Domaines de recherche:
SARS-CoV-2 PLpro-IN-2 (Compound 12) is a highly selective SARS-CoV-2 papain-like protease (PLpro) inhibitor of (IC50=0.06 μM). SARS-CoV-2 PLpro-IN-2 inhibits viral replication and immune evasion. SARS-CoV-2 PLpro-IN-2 exhibits antiviral efficacy in HeLa-ACE2 cells (EC50=2.9 μM). SARS-CoV-2 PLpro-IN-2 is promising for research of COVID-19 .
Cat. No.: HY-170767
SARS-CoV-2-IN-109 (compound 50) is an inhibitor targeting SARS-CoV with in vivo anti-infection activity. SARS-CoV-2-IN-109 targets the interaction between the SARS-CoV-2 Spike receptor-binding domain (RBD) and the human receptor angiotensin-converting enzyme 2 (ACE2) (EC50=26.5 μM), blocking the entry of SARS-CoV-2 into VeroE6 cells (EC50=17.0 μM). The CC50 of SARS-CoV-2-IN-109 for VeroE6 cells is >100 μM .
Cat. No.: HY-N11608
CAS No.: 95753-52-9
Target:
Synonyms: Ursodeoxycholate (Standard); Ursodiol (Standard); UDCA (Standard)
Cat. No.: HY-N2116R
CAS No.: 111047-30-4
Cat. No.: HY-W051612
CAS No.: 16900-57-5
Domaines de recherche:
Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Endocrinology
DL-Propargylglycine hydrochloride is an irreversible and selective CSE inhibitor that blocks the biosynthesis of endogenous hydrogen sulfide. DL-Propargylglycine hydrochloride induces ROS and TGF-β1 expression. DL-Propargylglycine hydrochloride downregulates carotid ACE2 and Ang-(1-7), and elevates Ang II. DL-Propargylglycine hydrochloride upregulates ICAM-1/LFA-1, exacerbating Aspirin (HY-14654)-induced gastric mucosal injury. DL-Propargylglycine hydrochloride is used in research on diabetes-induced liver injury, diabetic nephropathy, atherosclerosis, gastric mucosal injury, hemorrhagic shock, and Streptococcus agalactiae infection [2] .
Cat. No.: HY-179634
Domaines de recherche:
ASF-006 sodium, a tetrapodal tryptophan derivative, is a potent viral invasion inhibitor. ASF-006 sodium shows potent antiviral activity against different SARS-CoV-2 Omicron variants but not against the ancestral SARS-CoV.2 strain (Wuhan-Hu-1). ASF-006 sodium competitively inhibits receptor-binding domain (RBD)-ACE2 binding via an allosteric mechanism. ASF-006 sodium inhibits Omicron BA.1, Omicron XBB.1.5, respiratory syncytial virus (RSV) and Ebola virus infection with IC50s of 0.02 μM, 0.3 μM, 1.52 μM and 0.2 μM, respectively. ASF-006 sodium inhibits cell entry of both HIV and enterovirus A71[1].
Cat. No.: HY-P990814
Cat. No.: HY-P990815
Cat. No.: HY-RS00154
Target:
Domaines de recherche:
ACER2 Human Pre-designed siRNA Set A contains three designed siRNAs for ACER2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990180
Domaines de recherche:
Cat. No.: HY-118060R
CAS No.: 24587-37-9
Synonyms: N-Valyltryptophan (Standard); Val-Trp (Standard)
Domaines de recherche:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
