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240

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By Targets:	5-HT Receptor (3) Acyltransferase (1) Adenosine Receptor (1) Akt (1) Aminotransferases (Transaminases) (1) Amyloid-β (1) Apoptosis (2) Arp2/3 Complex (1) Aurora Kinase (1) Autophagy (7) Bacterial (4) Biochemical Assay Reagents (3) Calmodulin (1) Casein Kinase (1) CaSR (3) Checkpoint Kinase (Chk) (2) Cholinesterase (ChE) (1) DNA/RNA Synthesis (1) Drug Derivative (1) Drug Intermediate (1) EGFR (3) Elastase (1) Endogenous Metabolite (11) Epigenetic Reader Domain (2) Estrogen Receptor/ERR (1) Ferroptosis (1) FGFR (1) FLT3 (1) Glucokinase (2) HDAC (1) iGluR (1) Influenza Virus (1) Isotope-Labeled Compounds (7) JNK (2) Ligands for E3 Ligase (1) Liposome (1) Lipoxygenase (1) MDM-2/p53 (1) mGluR (1) Microtubule/Tubulin (1) Mixed Lineage Kinase (1) Monoamine Oxidase (2) mTOR (1) Myosin (4) Necroptosis (1) P2X Receptor (1) P2Y Receptor (2) p97 (2) Parasite (3) PARP (1) PDGFR (1) Phosphodiesterase (PDE) (1) PI3K (4) PKA (5) PKC (5) Potassium Channel (2) PROTACs (2) Ras (2) Reactive Oxygen Species (ROS) (1) Reference Standards (7) RIP kinase (1) ROCK (4) Ser/Thr Kinase (1) Small Interfering RNA (siRNA) (2) Sodium Channel (1) Src (1) TGF-β Receptor (2) Thyroid Hormone Receptor (2) Tyrosinase (1) VEGFR (4)
By Research Areas:	Cancer (37) Cardiovascular Disease (4) Endocrinology (5) Infection (6) Inflammation/Immunology (10) Metabolic Disease (9) Neurological Disease (23)
Click Chemistry:	Alkynes (2)
Oligonucleotides:	Phospholipids (2) Human Pre-designed siRNA Sets (2) siRNAs (2)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

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Elastase, Porcine pancreas 4 Publications Verification EC 3.4.21.36; Pancreatopeptidase E	Elastase	Metabolic Disease
Elastase, Porcine pancreas (EC 3.4.21.36) is a single polypeptide chain of 240 amino acid residues, derived from pig pancreas. Elastase, Porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters .

Lignoceric acid 2 Publications Verification Tetracosanoic acid	Endogenous Metabolite	Neurological Disease
Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research .

ERG240 5 Publications Verification	Aminotransferases (Transaminases)	Inflammation/Immunology Cancer
ERG240 is an oral active branched-chain amino acid aminotransferase 1 (BCAT1) inhibitor. ERG240 can be used for the research of cancer, rheumatoid arthritis, and bone disease .

ICA-121431 4 Publications Verification	Sodium Channel	Cardiovascular Disease
ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Na_v) blocker, shows equipotent selectivity for human Na_v1.1 and Na_v1.3 subtypes with IC₅₀ values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Na_v1.2 (IC₅₀=240 nM) and 1,000 fold selectivity against Na_v1.4, Na_v1.6, and the TTX-resistant human Na_v1.5 and Na_v1.8 channels (IC₅₀s >10 μM).

ML240 5 Publications Verification	p97	Cancer
ML240 is a potent p97 inhibitor, inhibiting p97 ATPase with IC₅₀ value of 100 nM.

LDN-212854 1 Publications Verification	TGF-β Receptor	Cancer
LDN-212854 is a bone morphogenetic protein (BMP) inhibitor that potently inhibits ALK2 (IC₅₀: 1.3 nM). LDN-212854 also inhibits ALK1 (IC₅₀: 2.40 nM). LDN-212854 can be used in the research of fibrodysplasia ossificans progressive and cancers, such as hepatocellular carcinoma (HCC) .

*20 mM HEPES, 150 mM NaCl, 240* mM Sucrose, pH 7.2 buffer**	Biochemical Assay Reagents	Others
The 20 mM HEPES, 150 mM NaCl, 240 mM Sucrose, pH 7.2 buffer is a physiological buffer composed of 20 mM HEPES, 150 mM NaCl and 240 mM Sucrose, adjusted to pH 7.2, which is used to resuspend human erythrocyte ghost preparations .

ART812 3 Publications Verification	DNA/RNA Synthesis	Cancer
ART812 is an orally active DNA polymerase Polθ inhibitor with an IC₅₀ value of 7.6 nM. ART812 has an IC₅₀ value of 240 nM for cell based microhomology-mediated end joining (MMEJ) .

Brivanib 2 Publications Verification BMS-540215	VEGFR Autophagy	Cancer
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with an IC₅₀ of 25 nM, and has moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β .

(R)-(-)-Rolipram 2 Publications Verification (R)-Rolipram; (-)-Rolipram	Phosphodiesterase (PDE)	Neurological Disease
(R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterases PDE4 with IC₅₀ of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.

HA-100 1 Publications Verification	PKA PKC Myosin ROCK	Cancer
HA-100 is a potent protein kinase inhibitor, with IC₅₀s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 also used as a ROCK inhibitor .

Ginkgolic Acid (C13:0) Ginkgolic acid (13:0); Ginkgoneolic Acid; 6-Tridecylsalicylic acid	Bacterial PI3K Parasite	Infection Inflammation/Immunology
Ginkgolic Acid (C13:0) (Ginkgoneolic Acid) is an anti-cariogenic agent and a PI3Kδ inhibitor (IC₅₀: 2.49 μM). Ginkgolic Acid (C13:0) exhibits antibacterial and anti-parasitic activities. Ginkgolic Acid (C13:0) can also inhibit mast cell degranulation (IC₅₀: 2.40 μM) .

MK-0941	Glucokinase	Metabolic Disease
MK-0941 is a selective, orally active, and allosteric glucokinase activator with EC₅₀s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 activates hexokinase subtype IV. MK-0941 can increase insulin secretion and glucose uptake. MK-0941 can be studied in research for type 2 diabetes .

PD-161570	FGFR PDGFR EGFR Src TGF-β Receptor	Cardiovascular Disease Cancer
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC₅₀ of 39.9 nM and a K_i of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC₅₀ values of 310 nM, 240 nM, and 44 nM, respectively. PD-161570 inhibits PDGF-stimulated autophosphorylation and FGF-1 receptor phosphorylation with IC₅₀s of 450 nM and 622 nM, respectively . PD-161570 is also a bone morphogenetic proteins (BMPs) and TGF-β signaling inhibitor .

MS402 2 Publications Verification	Epigenetic Reader Domain	Inflammation/Immunology Cancer
MS402 is a BD1-selective BET BrD inhibitor with K_is of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1) and BRD2(BD2), respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice .

24:0 Lyso PC	Liposome	Others
24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .

Upacicalcet sodium SK-1403; AJT240; PLS240	CaSR	Endocrinology
Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC₅₀ = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca ²⁺ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet sodium is useful for studying SHPT .

Brivanib (alaninate) 2 Publications Verification BMS-582664	VEGFR Autophagy	Cancer
Brivanib alaninate (BMS-582664) is an ATP-competitive inhibitor against VEGFR2 with an IC₅₀ of 25 nM; has moderate potency against VEGFR-1 and FGFR-1, but more than 240-fold against PDGFRβ .

BDP-13176 1 Publications Verification	Arp2/3 Complex	Cancer
BDP-13176 is a potent fascin 1 inhibitor, with a K_d of 90 nM and an IC₅₀ of 240 nM. BDP-13176 has potential as an anti-metastatic agent .

PROTAC EGFR degrader 9	PROTACs EGFR Apoptosis	Cancer
PROTAC EGFR degrader 9 (Compound C6) is an orally active CRBN-based PROTAC EGFR degrader. PROTAC EGFR degrader 9 exhibits a DC₅₀ of 10.2 nM and a K_d of 240.2 nM against EGFR ^{L858R/T790M/C797S}. PROTAC EGFR degrader 9 exhibits potent degradation activity against various EGFR mutants, while sparing the EGFRWT. (Blue: CRBN ligand (HY-A0003), Black: linker (HY-161613); Pink: EGFR inhibitor (HY-161537)) .

PARP1 PROTAC 180055 1 Publications Verification	PROTACs PARP	Cancer
PARP1 PROTAC 180055 (Compound 180055) is a selective PARP1 PROTAC degrader (DC₅₀ in T47D and MDA-MB-231 cell lines is 180 nM and 240 nM, respectively). PARP1 PROTAC 180055 promotes ubiquitination and degradation of PARP1 as well as inhibits PARP1 enzyme activity without a noticeable DNA trapping effect. PARP1 PROTAC 180055 inhibits tumors carrying BRCA mutations with a minor impact on the growth of normal cells (Pink: PARP1 ligand (HY-10617A); Blue: E3 ligase VHL ligand (HY-125845); Black: linker (HY-W014787)) .

3,5-Diiodothyropropionic acid 1 Publications Verification	Thyroid Hormone Receptor	Cardiovascular Disease Endocrinology
3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with K_a of 2.40 and 4.06 M ^-1 for TRα1 and TRβ1, respectively. 3,5-Diiodothyropropionic acid promotes angiogenesis in 3-D human dermal microvascular endothelial cell sprouting assay. 3,5-Diiodothyropropionic acid prevents myocardial arteriolar loss in thyroidectomized rats and enhances cardiac energy-generating capacity in postinfarction heart failure rats. 3,5-Diiodothyropropionic can be used in studies related to angiogenesis and heart failure .

Indophagolin	P2X Receptor 5-HT Receptor Autophagy	Cancer
Indophagolin is a potent, indoline-containing autophagy inhibitor (IC₅₀=140 nM). Indophagolin antagonizes the purinergic receptor P2X₄ as well as P2X₁ and P2X₃ with IC₅₀s of 2.71, 2.40 and 3.49 μM, respectively. Indophagolin also antagonizes the G_q-protein-coupled P2Y₄, P2Y₆, and P2Y₁₁ receptors (IC₅₀s =3.4~15.4 μM). Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT₆ (IC₅₀=1.0 μM) and a moderate effect on receptors 5-HT_1B, 5-HT_2B, 5-HT_4e, and 5-HT₇ .

Aurora kinase inhibitor-2	Aurora Kinase	Cancer
Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC₅₀s of 310 nM and 240 nM for Aurora A and Aurora B, respectively .

VU0361737 ML-128	mGluR	Neurological Disease
VU0361737 (ML-128) is a potent, selective and CNS penetrant positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR₄ PAM), with EC₅₀s of 240 nM and 110 nM for human and rat mGluR₄ receptors, respectively. VU0361737 has neuroprotective effect. VU0361737 is potential for Parkinson's disease research .

W-5 hydrochloride	Calmodulin	Neurological Disease
W-5 hydrochloride is a calmodulin antagonist. W-5 hydrochloride inhibits phosphodiesterase activation with an IC₅₀ value of 240 µM. W-5 hydrochloride can be used as a negative control for W-7 (HY-100912) .

Lignoceric acid-d47 Tetracosanoic acid-d₄₇	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Lignoceric acid-d₄₇ is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research .

IQ-1S free acid 1 Publications Verification	JNK	Inflammation/Immunology Cancer
IQ-1S free acid is a prospective inhibitor of NF-κB/activating protein 1 (AP-1) activity with an IC₅₀ of 2.3±0.41 μM. IQ-1S free acid has binding affinity (K_d values) in the nanomolar range for all three JNKs with K_ds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.

MRTX-EX185 formic	Ras	Cancer
MRTX-EX185 formic is a potent KRAS (G12D) inhibitor with an IC₅₀ of 90 nM. MRTX-EX185 formic can binds both GDP-loaded and active GNP states of KRAS and KRAS (G12D). MRTX-EX185 formic exhibits broad-spectrum binding properties with IC₅₀s of 110, 290, 130 and 240 nM for KRAS WT, KRAS (G12C), KRAS (Q61H), KRAS (G13D). MRTX-EX185 formic also binds GDP-loaded HRAS. MRTX-EX185 formic can be used to study various RAS-driven tumors (such as pancreatic cancer) .

Lignoceric acid-d4-2 Tetracosanoic acid-d₄-2	Endogenous Metabolite	Neurological Disease
Lignoceric acid-d₄-2 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research .

Lignoceric acid-d4-1	Endogenous Metabolite	Neurological Disease
Lignoceric acid-d₄-11 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research .

AS-041164	PI3K	Inflammation/Immunology
AS-041164 is a potent, selective and orally active PI3Kγ isoform inhibitor with an IC₅₀ of 70 nM. AS-041164 shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC₅₀s of 240 nM, 1.45 μM, and 1.70 μM, respectively). AS-041164 has anti-inflammatory effects .

DU125530	5-HT Receptor	Neurological Disease
DU125530 is a potent and selective5-HT1A receptor antagonist with K_i values of 0.7, 890, 1200, 240, 750, 1100 nM for 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2C, 5-HT3, respectively. DU125530 shows antidepressant effects .

24:0 Lyso PC-d4	Isotope-Labeled Compounds	Others
24:0 Lyso PC-d₄4 is the deuterium labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .

TMEM240 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TMEM240 Human Pre-designed siRNA Set A contains three designed siRNAs for TMEM240 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ALOX5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ALOX5 Human Pre-designed siRNA Set A contains three designed siRNAs for ALOX5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PKC-IN-6	Ser/Thr Kinase Tyrosinase PKA PKC EGFR	Cancer
PKC-IN-6 (Compound 21) is a selective inhibitor of tyrosine and serine kinases. PKC-IN-6 shows inhibitory activity against PKC-α, PKC-δ, PKA, EGF-R with IC₅₀ values of 240, >500, >500, >100 μM, respectively. PKC-IN-6 is promising for research of cancers .

Lignoceric acid-d3 Tetracosanoic acid-d₃	Endogenous Metabolite	Neurological Disease
Lignoceric acid-d₃ is the deuterium labeled Lignoceric acid . Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research .

DQ661	Autophagy mTOR	Cancer
DQ661 is a potent PPT1 inhibitor. DQ661 is a dimeric quinacrine autophagy inhibitor. DQ661 inhibits mTORC1 activity. DQ661 decreases the protein expression of pS6K T389, pS6 S240-244. DQ661 shows anticancer activity .

MRTX-EX185	Ras	Cancer
MRTX-EX185 is a potent KRAS (G12D) inhibitor with an IC₅₀ of 90 nM. MRTX-EX185 can binds both GDP-loaded and active GNP states of KRAS and KRAS (G12D). MRTX-EX185 exhibits broad-spectrum binding properties with IC₅₀s of 110, 290, 130 and 240 nM for KRAS WT, KRAS (G12C), KRAS (Q61H), KRAS (G13D). MRTX-EX185 also binds GDP-loaded HRAS. MRTX-EX185 can be used to study various RAS-driven tumors (such as pancreatic cancer) .

IOR-160	Casein Kinase HDAC	Cancer
IOR-160 is a dual inhibitor of casein kinase 2 (CK2) and HDACs. IOR-160 exhibits high selectivity for CK2 (IC₅₀ = 1.7 nM) and broad inhibitory activity against HDAC (HDAC 1, 2, 3, and 6 with IC₅₀s of 3.3 nM, 24.0 nM, 3.9 nM, and 13.0 nM, respectively, with low activity for HDAC8). IOR-160 modulates key cellular signaling pathways by inhibiting AKT phosphorylation and increasing acetylated α-tubulin. IOR-160 inhibits tumor growth and reduces tumor burden through dual CK2/HDAC inhibition. IOR-160 is indicated for use in triple-negative breast cancer research .

Zharp1-163	Ferroptosis Necroptosis RIP kinase Reactive Oxygen Species (ROS) Mixed Lineage Kinase	Inflammation/Immunology
Zharp1-163 is a dual inhibitor of ferroptosis and necroptosis. Zharp1-163 effectively blocks ferroptosis by reducing reactive oxygen species (ROS) levels and inhibits necroptosis by potently and selectively targeting RIPK1 kinase activity (K_D = 240 nM; IC₅₀ = 406.1 nM). Zharp1-163 inhibits the cellular activation of RIPK1, RIPK3 and MLKL in response to necroptotic stimulation. Zharp1-163 markedly attenuates TNF-α (HY-P1875)-induced systemic inflammatory syndrome, including the prevention of TNF-α-induced mortality and hypothermia in mice. Zharp1-163 significantly alleviates acute kidney injury associated with both necroptosis and ferroptosis in models induced by Cisplatin (HY-17394) and ischemia-reperfusion. Zharp1-163 can be used for the study of diseases associated with cell death pathways, such as kidney disease .

CRBN ligand-240	Ligands for E3 Ligase	Cancer
CRBN ligand-240 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-240 can be linked to a target protein ligand via a linker to form a PROTAC.

ML240 (Standard)	p97	Cancer
ML240 (Standard) is the analytical standard of ML240. This product is intended for research and analytical applications. ML240 is a potent p97 inhibitor, inhibiting p97 ATPase with IC50 value of 100 nM.

ztz240	Potassium Channel	Neurological Disease
ztz240 is a chemical modulator of voltage-gated potassium channel Kv7 (KCNQ) (KCNQ2 and 3: EC₅₀=6.1 μM; KCNQ4: EC₅₀=12.2 μM). ztz240 can be used in analgesia and anti-epileptic research .

EU 1622-240	iGluR	Neurological Disease
EU 1622-240 is a biased positive allosteric modulator of GluN2B, GluN2C, and GluN2D, with EC₅₀s of 0.57, 0.82, 1.1 μM respectively. EU 1622-240 has good physicochemical properties, in vitro stability, and permeability .

Cat. No.	Product Name

HY-L240

Plant Hormone Library

45 compounds

Plant hormones are natural signaling molecules synthesized by plants themselves, serving as crucial chemical messengers that exert physiological effects on plants at extremely low concentrations. They coordinate cellular growth, division, differentiation, and organ formation, helping plants adapt to environmental changes. Major categories include abscisic acid, auxins, gibberellins, cytokinins, ethylene, and brassinosteroids, among others.

MCE has included 45 plant hormones, which can be used for identification in plant metabolomics and related botanical research.

HY-L0088V

Life Chemicals 50K Diversity Library

50,240 compounds

Life Chemicals presents a number of exclusive Pre-Plated Diversity Sets composed of 50,240 novel compounds with optimal physicochemical properties selected from Life Chemicals collection of newly synthesized items by dissimilarity search with an average Tanimoto threshold of 82%. These Diverse Screening Sets are ideal starting points for customers looking for a wide range of dissimilarity to screen against a number of targets from different classes or where little information is available on targeted protein structure.

Cat. No.	Product Name	Type

HY-150350

*20 mM HEPES, 150 mM NaCl, 240* mM Sucrose, pH 7.2 buffer**	Biochemical Assay Reagents
The 20 mM HEPES, 150 mM NaCl, 240 mM Sucrose, pH 7.2 buffer is a physiological buffer composed of 20 mM HEPES, 150 mM NaCl and 240 mM Sucrose, adjusted to pH 7.2, which is used to resuspend human erythrocyte ghost preparations .

HY-138622

24:0 Lyso PC	Biochemical Assay Reagents
24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .

Cat. No.	Product Name	Target	Research Area

HY-P10295

*p53 (232-240)*	MDM-2/p53	Cancer
p53 (232-240) is a peptide segment of the 232-240 amino acid sequence of the human tumor suppressor protein p53. p53 (232-240) enhances its binding affinity to the Major histocompatibility complex (MHC), thereby enhancing the immunogenicity of this peptide to enhance the immune system's response to tumor antigens. p53 (232-240) can be used in the development of cancer vaccines and in the study of tumor cell recognition and clearance by the immune system .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99880

Roledumab LFB-R593	Inhibitory Antibodies	Others
Roledumab (LFB-R593) is a human IgG1-κ antibody targeting RHD/CD240D. Roledumab is expressed by YB2/0 rat hybridoma cells .

HY-P990499

Anti-RHD/CD240d Antibody	Inhibitory Antibodies	Inflammation/Immunology
Anti-RHD/CD240d Antibody is a humanized antibody expressed in CHO cells that targets *RHD/CD240d. The Anti-RHD/CD240d* Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.4 kDa. The isotype control for Anti-RHD/CD240d Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99745

Morolimumab	Inhibitory Antibodies	Inflammation/Immunology
Morolimumab is an IgG1 human *anti-RHD/CD240D* monoclonal antibody. Morolimumab can be used for the research of immune disease .

Species:	Human (3)
Tag:	His (2) Tag Free (1) GST (1) Flag (1)
Source:	Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704438

	ALOX5 Protein, Human (His) ALOX5; Polyunsaturated fatty acid 5-lipoxygenase; Arachidonate 5-lipoxygenase (5-LO; 5-lipoxygenase; LOG5	Human	E. coli
	ALOX5 Protein, Human (His) is the recombinant human-derived ALOX5 protein, expressed by E. coli, with C-6*His tag.

HY-P701373

	CDK8-CCNC-MED12 Complex Protein, Human (Active, sf9, GST, FLAG, His) 1 Publications Verification CDK8; CCNC; MED12; Cyclin-dependent kinase 8; Cell division protein kinase 8; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; Protein kinase K35; Cyclin-C; SRB11 homolog; hSRB11; Mediator of RNA polymerase II transcription subunit 12; Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; Mediator complex subunit 12; OPA-containing protein; Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230; Trinucleotide repeat-containing gene 11 protein	Human	Sf9 insect cells
	The CDK8-CCNC-MED12 protein is an important component of the mediator complex, acting as a bridge for gene transcription regulation, transmitting information from gene-specific regulatory factors to RNA polymerase II. It is recruited to the promoter, assembles a preinitiation complex, and promotes transcription. CDK8-CCNC-MED12 Protein, Human (sf9, GST, FLAG, His) is the recombinant human-derived CDK8-CCNC-MED12 protein, expressed by sf9 insect cells , with N-6*His, N-Flag, N-GST labeled tag.

HY-P701363

	CDK19-CCNC-MED12 Protein, Human (sf9) CDK19; CCNC; MED12; Cyclin-dependent kinase 19; CDC2-related protein kinase 6; Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; Cyclin-dependent kinase 11; Death-preventing kinase; Cyclin-C; SRB11 homolog; hSRB11; Mediator of RNA polymerase II transcription subunit 12; Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; Mediator complex subunit 12; OPA-containing protein; Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230; Trinucleotide repeat-containing gene 11 protein	Human	Sf9 insect cells
	CDK19 plays a key role in cellular homeostasis and developmental programming. CDK19 can interact with p53 to inhibit p53-mediated transcription of p21, and regulates the proliferation of hematopoietic stem cells and acute myeloid leukemia cells. Besides, CDK19 is the paralog of CDK8. CDK8 and CDK19 can cooperate with each other in stimulating NFκB-induced transcription and Dengue virus replication. CDK19-CCNC-MED12 Protein, Human (sf9) is the recombinant human-derived CDK19-CCNC-MED12 protein, expressed by sf9 insect cells , with tag free. ,

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Host:	Mouse (1) Rabbit (6)
Reactivity:	Human (7) Rat (4) Mouse (7)
Application:	IHC-P (5) ICC/IF (6) IP (1) IHC-F (1) WB (7) FC (3)
Isotype:	IgG (6) IgG1 (1)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (7) Recombinant (4)
Modification:	Phosphorylated (2) Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P80269

	PDCD4 Antibody (YA240)	WB, ICC/IF, IHC-P, FC	Human, Mouse
	PDCD4 Antibody (YA240) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PDCD4.

HY-P86959

	MED12 Antibody (YA6652) Activator recruited cofactor 240 kDa component antibody; Activator-recruited cofactor 240 kDa component antibody; ARC240 antibody; CAG repeat protein 45 antibody; CAGH45 antibody; HOPA antibody; KIAA0192 antibody; MED12 antibody; MED12_HUMAN antibody; Mediator complex subunit 12 antibody; Activator recruited cofactor 240 kDa component antibody; Activator-recruited cofactor 240 kDa component antibody; ARC240 antibody; CAG repeat protein 45 antibody; CAGH45 antibody; HOPA antibody; KIAA0192 antibody	WB	Human, Mouse, Rat
	MED12 Antibody (YA6652) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MED12.

HY-P82192

	5 Lipoxygenase Antibody (YA1937) 5-LO; 5-LOX; 5LPG; LOG5; MGC163204	WB, IHC-F, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	5 Lipoxygenase Antibody (YA1937) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to 5 Lipoxygenase.

HY-P81264A

	CHD3 Antibody (YA945) CHD3; Chromodomain-helicase-DNA-binding protein 3; CHD-3; ATP-dependent helicase CHD3; Mi-2 autoantigen 240 kDa protein; Mi2-alpha; Zinc finger helicase; hZFH	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	CHD3 Antibody (YA945) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CHD3.

HY-P81264

	CHD3 Antibody (YA944) CHD3; Chromodomain-helicase-DNA-binding protein 3; CHD-3; ATP-dependent helicase CHD3; Mi-2 autoantigen 240 kDa protein; Mi2-alpha; Zinc finger helicase; hZFH	WB, ICC/IF, IP	Human, Mouse, Rat
	CHD3 Antibody (YA944) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CHD3.

HY-P86147

	Phospho-RPS6(Ser240/Ser244) Antibody (YA5839) RPS6; OK/SW-cl.2; 40S ribosomal protein S6; Phosphoprotein NP33	WB, IHC-P, ICC/IF	Human, Mouse
	Phospho-RPS6(Ser240/Ser244) Antibody (YA5839) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-RPS6(Ser240/Ser244).

HY-P86147A

	Phospho-RPS6(Ser240/Ser244) Antibody (YA5839)(PBS only) RPS6; OK/SW-cl.2; 40S ribosomal protein S6; Phosphoprotein NP33	WB, IHC-P, ICC/IF	Human, Mouse
	Phospho-RPS6(Ser240/Ser244) Antibody (YA5839) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-RPS6(Ser240/Ser244).

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Cat. No.	Product Name		Classification

HY-145962A

MRTX-EX185 formic		Alkynes
MRTX-EX185 formic is a potent KRAS (G12D) inhibitor with an IC₅₀ of 90 nM. MRTX-EX185 formic can binds both GDP-loaded and active GNP states of KRAS and KRAS (G12D). MRTX-EX185 formic exhibits broad-spectrum binding properties with IC₅₀s of 110, 290, 130 and 240 nM for KRAS WT, KRAS (G12C), KRAS (Q61H), KRAS (G13D). MRTX-EX185 formic also binds GDP-loaded HRAS. MRTX-EX185 formic can be used to study various RAS-driven tumors (such as pancreatic cancer) .

HY-145962

MRTX-EX185		Alkynes
MRTX-EX185 is a potent KRAS (G12D) inhibitor with an IC₅₀ of 90 nM. MRTX-EX185 can binds both GDP-loaded and active GNP states of KRAS and KRAS (G12D). MRTX-EX185 exhibits broad-spectrum binding properties with IC₅₀s of 110, 290, 130 and 240 nM for KRAS WT, KRAS (G12C), KRAS (Q61H), KRAS (G13D). MRTX-EX185 also binds GDP-loaded HRAS. MRTX-EX185 can be used to study various RAS-driven tumors (such as pancreatic cancer) .

Cat. No.	Product Name		Classification

HY-138622

24:0 Lyso PC		Phospholipids
24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .

HY-RS14707

TMEM240 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TMEM240 Human Pre-designed siRNA Set A contains three designed siRNAs for TMEM240 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS00620

ALOX5 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ALOX5 Human Pre-designed siRNA Set A contains three designed siRNAs for ALOX5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-N15767

24:0 CPE (d18:1/24:0)		Phospholipids
24:0 CPE (d18:1/24:0) is a phosphosphingolipid.

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