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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
APT1
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "APT1" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: GNF-Pf-1127
Target:
Research Areas:
ML348 (GNF-Pf-1127) is a selective and reversible acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM, and barely inhibits LYPLA2 [1].
1
Target:
Research Areas:
Apostatin-1 (Apt-1) is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N (KD=2.17 μM), disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, α-synuclein, or huntingtin [1].
1
1
1 Cited Publications
Cat. No.: HY-P700176AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FASLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Ant
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P700520
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FASLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Ant
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P700052AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FASLG; TNLG1A; Prev. APT1LG1; CD95L; Prev. TNFSF6; APTL; FasL; Tumor Necrosis Factor (Ligand) Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6; Mutant Tumor Necrosis Factor Family Member 6; Fas Antigen Ligand; Apoptosis (APO-1) Antigen Ligand 1; CD95 Ligand; Tumor Necrosis Factor Ligand 1A; CD178; CD178 Antigen; Fas Ligand (TNF Superfamily, Member 6); ALPS1B; Apoptosis Antigen Ligand; FASL; Fas Ligand; CD95-L
Species:
Human
Source:
E. coli
Cat. No.: HY-W010947
CAS No.: 17695-48-6
Target:
Research Areas:
4-Methylumbelliferyl palmitate is a fluorescent esterase substrate. 4-Methylumbelliferyl palmitate is hydrolyzed by APT2 and APT1 thioesterases and lysosomal acid lipase (LAL). 4-Methylumbelliferyl palmitate can be used in research on lysosomal acid lipase deficiency (LAL-D) [1] .
Cat. No.: HY-152951
CAS No.: 1351669-68-5
Palmostatin M is a Ras signaling modulator that targets acyl-protein thioesterase 1 (APT1) and 2 (APT2) in cells, with an IC50 of 2.5 nM for APT1. Palmostatin M interferes with the depalmitoylation cycle of Ras and downregulates the overall Ras signaling pathway. Palmostatin M can be used in cancer-related research [1].
Cat. No.: HY-P7539
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LYPLA1; Palmitoyl-Protein Hydrolase; Lysophospholipase 1; APT1; Acyl-Protein Thioesterase 1; LysoPLA I; Lysophospholipase I; LPL-I; APT-1; HAPT1; LPL1; Lysophospholipid-Specific Lysophospholipase
Species:
Human
Source:
E. coli
Cat. No.: HY-RS07921
Target:
Research Areas:
LYPLA1 Human Pre-designed siRNA Set A contains three designed siRNAs for LYPLA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24321
Target:
Research Areas:
Lypla1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lypla1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P76330
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAS; Fas (TNF Receptor Superfamily, Member 6); Prev. TNFRSF6; Apoptosis Signaling Receptor FAS; Prev. APT1; Apo-1 Antigen; Prev. FAS1; CD95 Antigen; Tumor Necrosis Factor Receptor Superfamily Member 6; Mutant Tumor Necrosis Receptor Superfamily Member 6;
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-RS16712
Target:
Research Areas:
Fas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70329
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAS; Fas (TNF Receptor Superfamily, Member 6); Prev. TNFRSF6; Apoptosis Signaling Receptor FAS; Prev. APT1; Apo-1 Antigen; Prev. FAS1; CD95 Antigen; Tumor Necrosis Factor Receptor Superfamily Member 6; Mutant Tumor Necrosis Receptor Superfamily Member 6;
Species:
Human
Source:
HEK293
Cat. No.: HY-P73049
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAS; Fas (TNF Receptor Superfamily, Member 6); Prev. TNFRSF6; Apoptosis Signaling Receptor FAS; Prev. APT1; Apo-1 Antigen; Prev. FAS1; CD95 Antigen; Tumor Necrosis Factor Receptor Superfamily Member 6; Mutant Tumor Necrosis Receptor Superfamily Member 6;
Species:
Rat
Source:
HEK293
Cat. No.: HY-P73047
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAS; Fas (TNF Receptor Superfamily, Member 6); Prev. TNFRSF6; Apoptosis Signaling Receptor FAS; Prev. APT1; Apo-1 Antigen; Prev. FAS1; CD95 Antigen; Tumor Necrosis Factor Receptor Superfamily Member 6; Mutant Tumor Necrosis Receptor Superfamily Member 6;
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
