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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
APT1
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "APT1" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: GNF-Pf-1127
Target:
Research Areas:
ML348 (GNF-Pf-1127) is a selective and reversible acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM, and barely inhibits LYPLA2 [1].
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Apostatin-1 (Apt-1) is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N (KD=2.17 μM), disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, α-synuclein, or huntingtin [1].
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1 Cited Publications
Cat. No.: HY-P700052AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: soluble Fas Ligand (sFasL); TNFSF6; CD95L; Apo I Ligand; APTL; APT1LG1; CD178
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1 Cited Publications
Cat. No.: HY-P700176AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: soluble Fas Ligand (sFasL); TNFSF6; CD95L; Apo I Ligand; APTL; APT1LG1; CD178; Fas-Lg; Tnfs; Tnlg1a; gld
Cat. No.: HY-152951
CAS No.: 1351669-68-5
Palmostatin M is a Ras signaling modulator that targets acyl-protein thioesterase 1 (APT1) and 2 (APT2) in cells, with an IC50 of 2.5 nM for APT1. Palmostatin M interferes with the depalmitoylation cycle of Ras and downregulates the overall Ras signaling pathway. Palmostatin M can be used in cancer-related research [1].
Cat. No.: HY-P76330
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; FAS; APT1; FAS1; TNFRSF6
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Source:
Cat. No.: HY-P76331
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; FAS; APT1; FAS1; TNFRSF6
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Cat. No.: HY-RS07921
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LYPLA1 Human Pre-designed siRNA Set A contains three designed siRNAs for LYPLA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24321
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Lypla1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lypla1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16712
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Fas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
