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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
BCMA
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "BCMA" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: Maleimidocaproyl monomethylauristatin F
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McMMAF (Maleimidocaproyl monomethylauristatin F) is an active molecule linker for ADC, made by coupling the powerful microtubule inhibitor Monomethyl auristatin F (MMAF) (HY-15579) with the protecting group maleimidocaproyl. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth .
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1 Cited Publications
Cat. No.: HY-P3239
CAS No.: 2050232-20-5
Synonyms: GSK2857916; Belantamab mafodotin-blm
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Belantamab mafodotin (GSK2857916) is composed of humanized and focused monoclonal antibody against B cell maturation antigen (BCMA) and McMMAF. The antibody portion is Belantamab (HY-P9980), and the drug-linker conjugate for ADC is McMMAF (HY-15578). Belantamab mafodotin has anti-myeloma activity .
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Cat. No.: HY-P99392
CAS No.: 2119595-80-9
Synonyms: JNJ-7957; JNJ-64007957; Tecvayli
Cat. No.: HY-P991155
CAS No.: 2988886-91-3
Synonyms: JNJ-79635322; JNJ-5322
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Cat. No.: HY-P990980
CAS No.: 2919209-65-5
Synonyms: CND-106; EMB-06
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Cat. No.: HY-P99798
CAS No.: 2251756-52-0
Synonyms: AMG 420; BI-836909
Cat. No.: HY-P9989
CAS No.: 2408319-25-3
Synonyms: REGN5458
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Cat. No.: HY-P99430
CAS No.: 2296827-07-9
Synonyms: EM901; CC-93269
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Cat. No.: HY-P991490
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Cat. No.: HY-P990070
CAS No.: 2642175-46-8
Synonyms: BION-1301
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Cat. No.: HY-P990095
CAS No.: 2408319-33-3
Synonyms: REGN5459
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Cat. No.: HY-P990785
CAS No.: 2490552-52-6
Synonyms: ABBV-383; TNB 383B
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Cat. No.: HY-P9980A
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Cat. No.: HY-146231A
Purity: 99.88%
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SS47 TFA, a PROTAC-based HPK1 degrader, exerts proteasome-mediated HPK1 degradation. The degradation of HPK1 via SS47 also significantly enhances the in vivo antitumor efficacy of BCMA CAR-T cell research. HPK1, an immunosuppressive regulatory kinase, is a promising target for cancer immunotherapies . SS47 (TFA) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-P1700
CAS No.: 2293841-58-2
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Cat. No.: HY-P11257
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Cat. No.: HY-RS14807
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TNFRSF17 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF17 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16981
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Tnfrsf17 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf17 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
