26 Results for "

Bile acid derivatives

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Bile acid derivatives" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N1423
CAS No.: 475-31-0
Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA) .
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4
4 Cited Publications
Cat. No.: HY-N1423A
CAS No.: 863-57-0
Glycocholic acid sodium is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid sodium inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid sodium modulates related bile acid receptor signaling. Glycocholic acid sodium suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid sodium can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA) .
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4
4 Cited Publications
Cat. No.: HY-N1423B
CAS No.: 1192657-83-2
Glycocholic acid hydrate is a bile acid derivative. Glycocholic acid hydrate downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid hydrate inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid hydrate modulates related bile acid receptor signaling. Glycocholic acid hydrate suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid hydrate can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA) .
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1
1 Cited Publications
Cat. No.: HY-N7121
CAS No.: 3521-62-8
Erythromycin estolate is the Erythromycin (HY-B0220) derivative , is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin estolate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin estolate toxicity is related to its inhibitory effect on bile acid transport .
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Cat. No.: HY-Y0095
CAS No.: 107-36-8
Synonyms: 2-Hydroxyethanesulfonic acid
Isethionic acid (2-Hydroxyethanesulfonic acid) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis .
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Cat. No.: HY-N1423S
CAS No.: 1201918-15-1
Glycocholic acid-d4 is the deuterium labeled Glycocholic acid (HY-N1423). Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA).
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Cat. No.: HY-W073080
CAS No.: 69477-27-6
Coproporphyrin I dihydrochlorideIt is an organic compound belonging to the class of porphyrins. It is a derivative of heme, an iron-containing molecule found in hemoglobin and other proteins. Coproporphyrin I dihydrochlorideOften used as a biomarker in the assessment of certain liver and metabolic diseases, especially those related to bile synthesis and transport. It can also be used as a reference standard for analytical chemistry and pharmacological research.
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Cat. No.: HY-133971
CAS No.: 1250-95-9
Purity:  98.40%
Synonyms: 5α,6α-Epoxycholesterol
Target:  

Liposome

Research Areas:  

Others

Cholesterol-5α,6α-epoxide is an epoxide derivative of cholesterol formed by the enzymatic oxidation of cholesterol in the liver and other tissues. Cholesterol-5α,6α-epoxide has unique chemical properties that make it an important intermediate in the biosynthesis of bile acids, which play a key role in the digestion and absorption of dietary fats. It also has a potential physiological role in regulating cholesterol metabolism and transport, although its biological function is not fully understood.
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Cat. No.: HY-W040201
CAS No.: 82473-24-3
Synonyms: 3-[3-(Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
CHAPSO is a bile derivative. CHAPSO reduces protein adsorption, improves the cryo-EM imaging quality. CHAPSO can be used as a detergent, or as the membrane protein solubilization and reconstruction reagent in membrane protein structural studies .
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Cat. No.: HY-W013105
CAS No.: 338950-81-5
Synonyms: N-Cholylglycine sodium salt, 98%
Sodium glycocholate hydrate, 98% is a bile acid derivative. Sodium glycocholate hydrate, 98% downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Sodium glycocholate hydrate, 98% inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Sodium glycocholate hydrate, 98% modulates related bile acid receptor signaling. Sodium glycocholate hydrate, 98% suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Sodium glycocholate hydrate, 98% can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA) .
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Cat. No.: HY-Y1173
CAS No.: 1562-00-1
Synonyms: 2-Hydroxyethanesulfonic acid sodium; Sodium isethionate
Isethionic acid sodium salt (2-Hydroxyethanesulfonic acid sodium; Sodium isethionate) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid sodium salt forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid sodium salt enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis .
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Cat. No.: HY-169393
CAS No.: 135013-42-2
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

N-Butyl lithocholic acid is a derivative of the secondary bile acid Lithocholic acid (HY-B0172) .
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Cat. No.: HY-177795
CAS No.: 6868-73-1
Synonyms: 3,6-Diketo-LCA
Target:  

Drug Derivative

Research Areas:  

Others

5β-Cholanic acid-3,6-dione (3,6-Diketo-LCA) is a similar substance to Lithocholic acid (LCA) (HY-B0172). 5β-Cholanic acid-3,6-dione cannot activate the Vitamin D receptor (VDR), and can be used as a negative control for studying the relationship between LCA derivatives and VDR .
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Cat. No.: HY-N1423S1
CAS No.: 2170091-95-7
Glycocholic acid-d5 is the deuterium labeled Glycocholic acid (HY-N1423). Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA).
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Cat. No.: HY-171117
CAS No.: 111929-13-6
Synonyms: 1β-Hydroxyglycodeoxycholic acid
1β-OH Glycine DCA (Compound Glyco 1β,3α,12α-triol) is a bile acid derivative .
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Cat. No.: HY-N15854
CAS No.: 80875-93-0
Category:  

Lipids

3α,6β,7α,12α-Tetrahydroxy bile acid is a tetrahydroxy derivative of bile acids.
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Cat. No.: HY-N15788
CAS No.: 80875-92-9
Category:  

Lipids

Target:  

Endogenous Metabolite

3α,6α,7α,12α-Tetrahydroxy bile acid is a hydrophilic tetrahydroxy derivative of bile acids.
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Cat. No.: HY-156074
CAS No.: 134-36-1
Erythromycin propionate, erythromycin (HY-B0220) derivative , is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin propionate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin propionate toxicity is related to its inhibitory effect on bile acid transport .
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Cat. No.: HY-N1423AR
CAS No.: 863-57-0
Glycocholic acid (sodium) (Standard) is the analytical standard of Glycocholic acid sodium (HY-N1423A). This product is intended for research and analytical applications. Glycocholic acid sodium is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid sodium inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid sodium modulates related bile acid receptor signaling. Glycocholic acid sodium suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid sodium can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA).
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Cat. No.: HY-W754548
Glycocholic acid- 13C2,d4 is the deuterium labeled and 13C-labeled Glycocholic acid (HY-N1423). Glycocholic acid is a bile acid derivative. Glycocholic acid downregulates MDR1, Bcl-2, MRP1, MRP2 and FXR, upregulates Bax, p53, caspase-9, caspase-3, TGR5 and S1PR2. Glycocholic acid inhibits multidrug resistance and efflux pumps, induces mitochondrial apoptosis, and enhances chemosensitivity. Glycocholic acid modulates related bile acid receptor signaling. Glycocholic acid suppresses growth and conjugation of Enterobacteriaceae and increases their antibiotic susceptibility. Glycocholic acid can be used for the research of colon adenocarcinoma and cholangiocarcinoma (CCA).
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