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Results for "

CD3E

" in MedChemExpress (MCE) Product Catalog:

36

Inhibitors & Agonists

35

Inhibitory Antibodies

51

Recombinant Proteins

5

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P9963
    Blinatumomab
    2 Publications Verification

    bscCD19xCD3; AMG-103; MEDI-538; MT-103; BLINCYTO

    CD19 Cancer
    Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia [3] .
    Blinatumomab
  • HY-P99909

    PF-06863135; RN-613

    TNF Receptor Inflammation/Immunology
    Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).
    Elranatamab
  • HY-P99332

    Anti-Human CD3E Recombinant Antibody; HuM291

    Apoptosis Inflammation/Immunology Cancer
    Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research .
    Visilizumab
  • HY-P990932

    BI 764532; OBT 620

    CD3 Cancer
    Obrixtamig (BI 764532; OBT 620) is an CD3E/DLL3-targeting L-κ-G1-h-CH2-CH3_L-λ-G1-h-CH2-CH3 type human antibody. Obrixtamig is a delta-like ligand 3 (DLL3)/CD3 IgG-like T-cell engager. Obrixtamig can be used for research of DLL3-positive small cell lung cancer .
    Obrixtamig
  • HY-P99868

    MGD 011

    CD19 CD3 Cancer
    Duvortuxizumab (MGD 011) is a chimeric humanized IG antibody targeting CD19 and CD3E .
    Duvortuxizumab
  • HY-P99896

    BTRC-4017A; RG-6194

    EGFR CD3 Cancer
    Runimotamab (BTRC-4017A) is a HER2 and CD3 T cell-engaging bispecific antibody. Runimotamab can decrease the size of liver tumor spheroids. Runimotamab can be studied in oncology research such as HER2-expressing cancers. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
    Runimotamab
  • HY-P99798

    AMG 420; BI-836909

    CD3 Cancer
    Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines .
    Pacanalotamab
  • HY-P990095

    REGN5459

    CD3 TNF Receptor Inflammation/Immunology Cancer
    Vonsetamig is a humanised immunoglobulin G4-kappa, anti-TNFRSF17 and CD3E bispecific antibody. Vonsetamig is an antineoplastic .
    Vonsetamig
  • HY-P990920

    MK-6070; HPN328

    CD3 Inflammation/Immunology
    HY-P990920 is an CD3E/ALB/DLL3-targeting (scFv-heavy-lamdba)-VH-VH' type chimeric humanized antibody .
    Gocatamig
  • HY-P99914

    GNC-038

    PD-1/PD-L1 CD19 TNF Receptor CD3 Interleukin Related IFNAR Inflammation/Immunology Cancer
    Emfizatamab (GNC-038) is a monoclonal antibody against CD19/CD3E/TNFRSF9/PD-L1. Emfizatamab exhibits antitumor activity, being capable of activating CD3 and 4-1BB signals on T cells, as well as targeting the high expression of CD19 or PD-L1 on tumor cells. Emfizatamab functions as a CD19-specific T cell engager by mediating direct antitumor activity. Emfizatamab can also overcome the inhibition of T cells by PD-L1. Emfizatamab can be used in the research of tumors such as R/R non-Hodgkin lymphoma or acute lymphoblastic leukemia .
    Emfizatamab
  • HY-P991034

    CD3 Inflammation/Immunology
    HY-P991034 is an EPCAM/CD3E-targeting H-γ1_L-κ-scFvhl dimer type bispecific antibody .
    Trevotamig
  • HY-P990903

    YMS-5A

    CD3 Inflammation/Immunology
    HY-P990903 is an CD3E/CD33-targeting [H-γ1 _ L-κ-scFv heavy -κ]-dimer type bispecific antibody .
    Avitotamig
  • HY-P990953

    Gen1047

    CD3 Cancer
    Zubotamig (Gen1047) is an CD3E/VTCN1-targeting Ig(G1 -κ_G1 -λ2) type chimeric human antibody. The recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Zubotamig induces T-cell mediated cytotoxicity of B7H4-positive tumor cells, triggers T-cell activation, and induces cytokine release from T cells in the presence of B7H4-expressing tumor cells. Zubotamig demonstrates antitumor activity in mouse patient-derived xenograft (PDX) models. Zubotamig can be used for the research of solid cancers (including breast, ovarian and lung cancer) .
    Zubotamig
  • HY-P991681

    ASP-2138

    Claudin CD3 Cancer
    Emaretamig is a humanized IgG1κ monoclonal antibody inhibitor targeting CLDN18 and CD3E. Abdakibart can be used for cancers like gastric and pancreatic cancer research .
    Emaretamig
  • HY-P990714

    CD3 Inflammation/Immunology
    Obertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv) .
    Obertamig
  • HY-P991708

    REGN-4336

    PSMA CD3 Cancer
    Olsutamig is a bivalent humanized IgG4κ monoclonal antibody inhibitor targeting FOLH1/PSMA and CD3E. Olsutamig simultaneously binds to PSMA on the tumor cell surface and CD3E on the T cell surface, markedly activating T cells and thereby specifically killing prostate cancer cells .
    Olsutamig
  • HY-P991671

    JNJ-80948543

    CD3 CD20 Transmembrane Glycoprotein Cancer
    Anafiltamig is a trivalent monoclonal antibody inhibitor targeting CD79B, CD3E and MS4A1. Anafiltamig consists of a humanized IgG1κ anti-CD79B arm and a bispecific scFv-based arm targeting CD3E and MS4A1. Anafiltamig simultaneously bridges T and B cells, activating T cells and specifically killing B cell tumors. Anafiltamig can be used for B cell malignancies such as non-Hodgkin lymphoma research .
    Anafiltamig
  • HY-P991686

    TNF Receptor CD3 Inflammation/Immunology Cancer
    Gamgertamig is a humanized IgG4 bispecific antibody targeting TNFRSF17 & CD3E .
    Gamgertamig
  • HY-P991700

    Claudin CD3 Cancer
    Lumivatamig is an H-γ1_L-κ-scFvhl dimer-type bispecific antibody targeting CLDN18.2 & CD3E .
    Lumivatamig
  • HY-RS02243

    Small Interfering RNA (siRNA) Others

    CD3E Human Pre-designed siRNA Set A contains three designed siRNAs for CD3E gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CD3E Human Pre-designed siRNA Set A
    CD3E Human Pre-designed siRNA Set A
  • HY-RS23464

    Small Interfering RNA (siRNA) Others

    Cd3e Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd3e gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Cd3e Rat Pre-designed siRNA Set A
    Cd3e Rat Pre-designed siRNA Set A
  • HY-P991469

    MEDI-565

    Transmembrane Glycoprotein Cancer
    AMG-211 (MEDI-565)i s a bispecific antibody targeting CD3E and CEACAM5/CEA/CD66e. AMG-211 can be used in Gastrointestinal cancer and Solid tumours research .
    AMG-211
  • HY-P991706

    Phosphodiesterase (PDE) CD3 Cancer
    Nelvutamig is a humanized immunoglobulin (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3) antibody targeting ENPP3/CD203c and CD3E. The corresponding isotype control is: Human immunoglobulin (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3) .
    Nelvutamig
  • HY-P991552

    CD3 Metabolic Disease Inflammation/Immunology
    AFM15 is a humanized monoclonal antibody inhibitor targeting CD3E. AFM15 can be used to study metabolic and immune system diseases, such as type 1 diabetes and inflammatory bowel disease (IBD) .
    AFM15
  • HY-P990939

    HPN 217

    TNF Receptor Inflammation/Immunology
    HY-P990939 is an CD3E/TNFRSF17-targeting VH-VH'-(scFv-heavy -λ) type chimeric antibody .
    Podentamig
  • HY-P990698

    PD-1/PD-L1 EGFR Inflammation/Immunology
    Umizortamig is an anti-CD3E/EGFR/TNFRSF9/PD-L1/CD3G monoclonal antibody .
    Umizortamig
  • HY-P991463

    CD3 Cancer
    MS133 is a human bispecific antibody (bsAb) targeting CD133/PROM1 & CD3E. MS133 can be used in colon cancer research .
    MS133
  • HY-RS17021

    Small Interfering RNA (siRNA) Others

    Cd3e Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd3e gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Cd3e Mouse Pre-designed siRNA Set A
    Cd3e Mouse Pre-designed siRNA Set A
  • HY-P992061

    CD3 Calcium Channel Inflammation/Immunology
    Anti-Mouse CD3E Antibody (500A2) is an antibody targeting mouse CD3ε, which specifically binds to the region on CD3ε adjacent to the T cell receptor binding site. Anti-Mouse CD3E Antibody (500A2) triggers functional signal transduction in immature T cells and activates naive T cells. When cross-linked, Anti-Mouse CD3E Antibody (500A2) induces a rapid, robust and transient increase in cytoplasmic calcium concentration, acting as a potent calcium flux inducer. Anti-Mouse CD3E Antibody (500A2) is suitable for multiple experimental techniques such as flow cytometry, immunoprecipitation and EMARS reactions. It can be used to detect CD3E expression on thymocytes, mature T lymphocytes and NK-T cells from different mouse strains, or to identify membrane cluster components of the TCR complex, and shows no cross-reactivity with rat leukocytes [3].
    Anti-Mouse CD3E Antibody (500A2)
  • HY-P991461

    XmAb968

    CD38 Cancer
    AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 & CD3E. AMG-424 kills CD38-expressing cancer cells, triggers T-cell proliferation and attenuates cytokine release. AMG 424 has antitumor activity in a bone marrow-invasive mouse cancer model and induces peripheral B-cell depletion in cynomolgus monkeys. AMG-424 can be used in multiple myeloma research. Recommended isotype control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3 .
    AMG-424
  • HY-P990692

    JNJ-70218902; JNJ-902

    CD3 Inflammation/Immunology
    Ciduvectamig is an anti-CD3E/TMEFF2 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
    Ciduvectamig
  • HY-P990955

    ADX-097

    CD3 Inflammation/Immunology
    HY-P990955 is an CD3E-targeting IgG4κ type chimeric antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
    Ebribafusp alfa
  • HY-P992136

    CD3 Others
    Torutamig is a monoclonal antibody targeting TNFRSF17/BCMA/CD269&CD3E .
    Torutamig
  • HY-P992140

    CD3 EGFR Others
    Varzutamig is a bispecific antibody targeting CD3E/ALB/EGFR .
    Varzutamig
  • HY-P992145

    CD3 Others
    Zeclantamig is an immunoglobuline (H-gamma1_L-kappa)_scFvhk-G1(h-CH2-CH3), anti-[Homo sapiens EPCAM et anti-[Homo sapiens CD3E], anticorps monoclonal chimérique, bispécifique, trivalent .
    Zeclantamig
  • HY-P992370

    Interleukin Related IFNAR Cancer
    HPN601 is a protease-activated EpCAM-targeting T-cell engager that binds EpCAM competitively and induces T-cell mediated tumor cell killing. HPN601 binds to EpCAM, CD3e and albumin; albumin binding extends its half-life, while masking groups keep the molecule inert outside the tumor microenvironment. HPN601 significantly reduces the release levels of IFN-γ, IL-2, IL-6 and IL-10. HPN601 can be used in research related to cancers such as breast cancer and gastric cancer .
    HPN601

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