92 Results for "

CD3E

" in MedChemExpress (MCE) Product Catalog:
Products (92)

92 Results for "CD3E" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P9963
CAS No.: 853426-35-4
Synonyms: bscCD19xCD3; AMG-103; MEDI-538; MT-103; BLINCYTO

Target:  

CD19

Research Areas:  

Cancer

Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia [3] .
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1
1 Cited Publications
Cat. No.: HY-P80598
Synonyms: CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3E

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-P99909
CAS No.: 2408850-14-4
Synonyms: PF-06863135; RN-613

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P99332
CAS No.: 219716-33-3
Synonyms: Anti-Human CD3E Recombinant Antibody; HuM291

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research .
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Cat. No.: HY-P990932
CAS No.: 2851943-09-2
Synonyms: BI 764532; OBT 620

Target:  

CD3

Research Areas:  

Cancer

Obrixtamig (BI 764532; OBT 620) is an CD3E/DLL3-targeting L-κ-G1-h-CH2-CH3_L-λ-G1-h-CH2-CH3 type human antibody. Obrixtamig is a delta-like ligand 3 (DLL3)/CD3 IgG-like T-cell engager. Obrixtamig can be used for research of DLL3-positive small cell lung cancer .
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Cat. No.: HY-P99868
CAS No.: 1831098-91-9
Synonyms: MGD 011

Target:  

CD19 CD3

Research Areas:  

Cancer

Duvortuxizumab (MGD 011) is a chimeric humanized IG antibody targeting CD19 and CD3E .
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Cat. No.: HY-P99896
CAS No.: 2361325-98-4
Synonyms: BTRC-4017A; RG-6194

Target:  

EGFR CD3

Research Areas:  

Cancer

Runimotamab (BTRC-4017A) is a HER2 and CD3 T cell-engaging bispecific antibody. Runimotamab can decrease the size of liver tumor spheroids. Runimotamab can be studied in oncology research such as HER2-expressing cancers. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P99798
CAS No.: 2251756-52-0
Synonyms: AMG 420; BI-836909

Target:  

CD3

Research Areas:  

Cancer

Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines .
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Cat. No.: HY-P99418
CAS No.: 2314491-93-3
Synonyms: AMG-160

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Acapatamab (AMG-160) is an anti-CD3E/FOLH1 monoclonal antibody .
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Cat. No.: HY-P990920
CAS No.: 2851862-91-2
Synonyms: MK-6070; HPN328

Target:  

CD3

Research Areas:  

Cancer

HY-P990920 is an CD3E/ALB/DLL3-targeting (scFv-heavy-lamdba)-VH-VH' type chimeric humanized antibody .
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Cat. No.: HY-P99914
CAS No.: 2559704-23-1
Synonyms: GNC-038
Emfizatamab (GNC-038) is a monoclonal antibody against CD19/CD3E/TNFRSF9/PD-L1. Emfizatamab exhibits antitumor activity, being capable of activating CD3 and 4-1BB signals on T cells, as well as targeting the high expression of CD19 or PD-L1 on tumor cells. Emfizatamab functions as a CD19-specific T cell engager by mediating direct antitumor activity. Emfizatamab can also overcome the inhibition of T cells by PD-L1. Emfizatamab can be used in the research of tumors such as R/R non-Hodgkin lymphoma or acute lymphoblastic leukemia .
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Cat. No.: HY-P99912
CAS No.: 2250261-27-7
Synonyms: AMG-673

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Emerfetamab is an anti-CD3E/CD33 monoclonal antibody .
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Cat. No.: HY-P991034
CAS No.: 2920215-79-6

Target:  

CD3

Research Areas:  

Inflammation/Immunology

HY-P991034 is an EPCAM/CD3E-targeting H-γ1_L-κ-scFvhl dimer type bispecific antibody .
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Cat. No.: HY-P990903
CAS No.: 2577961-36-3
Synonyms: YMS-5A

Target:  

CD3

Research Areas:  

Inflammation/Immunology

HY-P990903 is an CD3E/CD33-targeting [H-γ1 _ L-κ-scFv heavy -κ]-dimer type bispecific antibody .
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Cat. No.: HY-P990953
CAS No.: 2640279-10-1
Synonyms: Gen1047

Target:  

CD3

Research Areas:  

Cancer

Zubotamig (Gen1047) is an CD3E/VTCN1-targeting Ig(G1 -κ_G1 -λ2) type chimeric human antibody. The recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Zubotamig induces T-cell mediated cytotoxicity of B7H4-positive tumor cells, triggers T-cell activation, and induces cytokine release from T cells in the presence of B7H4-expressing tumor cells. Zubotamig demonstrates antitumor activity in mouse patient-derived xenograft (PDX) models. Zubotamig can be used for the research of solid cancers (including breast, ovarian and lung cancer) .
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Cat. No.: HY-P991681
CAS No.: 3051701-97-1
Synonyms: ASP-2138

Target:  

Claudin CD3

Research Areas:  

Cancer

Emaretamig is a humanized IgG1κ monoclonal antibody inhibitor targeting CLDN18 and CD3E. Abdakibart can be used for cancers like gastric and pancreatic cancer research .
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Cat. No.: HY-P990714
CAS No.: 2750126-32-8

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Obertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv) .
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Cat. No.: HY-P991708
CAS No.: 3034664-43-9
Synonyms: REGN-4336

Target:  

PSMA CD3

Research Areas:  

Cancer

Olsutamig is a bivalent humanized IgG4κ monoclonal antibody inhibitor targeting FOLH1/PSMA and CD3E. Olsutamig simultaneously binds to PSMA on the tumor cell surface and CD3E on the T cell surface, markedly activating T cells and thereby specifically killing prostate cancer cells .
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Cat. No.: HY-P991671
CAS No.: 3009026-69-8
Synonyms: JNJ-80948543

Research Areas:  

Cancer

Anafiltamig is a trivalent monoclonal antibody inhibitor targeting CD79B, CD3E and MS4A1. Anafiltamig consists of a humanized IgG1κ anti-CD79B arm and a bispecific scFv-based arm targeting CD3E and MS4A1. Anafiltamig simultaneously bridges T and B cells, activating T cells and specifically killing B cell tumors. Anafiltamig can be used for B cell malignancies such as non-Hodgkin lymphoma research .
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Cat. No.: HY-P991686
CAS No.: 3038119-48-8

Target:  

TNF Receptor CD3

Research Areas:  

Inflammation/Immunology Cancer

Gamgertamig is a humanized IgG4 bispecific antibody targeting TNFRSF17 & CD3E .
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