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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
CMA
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "CMA" in MCE Product Catalog:
16
16 Publications Verification
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AR7 is an atypical RARA/RARα (retinoic acid receptor, alpha) antagonist. AR7 specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy .
8
8 Cited Publications
Cat. No.: HY-P1098
CAS No.: 151988-33-9
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8
8 Cited Publications
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CA77.1 is a potent, brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics. CA77.1 is a derivative of AR7 (HY-101106) and can increase the expression of the lysosomal receptor LAMP2A in?lysosomes. CA77.1 improves behavior and neuropathology in PS19 mice model and can be used for alzheimer's?disease research .
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8 Cited Publications
Cat. No.: HY-P1098A
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8
8 Cited Publications
Cat. No.: HY-P1098B
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7
7 Cited Publications
QX77 is a chaperone-mediated autophagy (CMA) activator and upregulates LAMP2A expression in vitro. QX77 induces Rab11 upregulation, rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells . QX77 can impede self-renewal and promote differentiation of ES cells .
2
2 Cited Publications
Cat. No.: HY-W013508
CAS No.: 106797-53-9
2
2 Cited Publications
FDW028 a potent and highly selective FUT8 inhibitor. FUT8 exhibits potent anti-tumor activity by defucosylation and impelling lysosomal degradation of B7-H3 through the chaperone-mediated autophagy (CMA) pathway. FDW028 can be used for metastatic colorectal cancer (mCRC) research .
Synonyms: Megakaryocytes/platelets inducing agent
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TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells .
Cat. No.: HY-RS02853
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CMA1 Human Pre-designed siRNA Set A contains three designed siRNAs for CMA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25804
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Cma1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cma1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02854
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CMAS Human Pre-designed siRNA Set A contains three designed siRNAs for CMAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-173150
CAS No.: 106928-29-4
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Cat. No.: HY-RS19313
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Cma1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cma1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-101106R
CAS No.: 80306-38-3
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AR7 (Standard) is the analytical standard of AR7 (HY-101106). This product is intended for research and analytical applications. AR7 is an atypical RARA/RARα (retinoic acid receptor, alpha) antagonist. AR7 specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy .
Cat. No.: HY-RS22126
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Cmas Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cmas gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28648
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Cmas Rat Pre-designed siRNA Set A contains three designed siRNAs for Cmas gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P74252
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Alpha-chymase; Mast cell chymase 1; Mast cell protease 5; mMCP-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
