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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
CRP
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "CRP" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: GNS561 hydrochloride
Research Areas:
Ezurpimtrostat hydrochloride (GNS561 hydrochloride) is an orally active PPT1 inhibitor, autophagy inhibitor, immunomodulator, anti-inflammatory agent, and anticancer agent. Ezurpimtrostat hydrochloride inhibits PPT1, dysregulates lysosomal function, redistributes mTOR, and induces apoptosis. Ezurpimtrostat hydrochloride reduces IFN‑α, CRP, immune complex deposition, and SARS‑CoV‑2 viral load. Ezurpimtrostat hydrochloride can be used for the study of systemic lupus erythematosus, SARS‑CoV‑2, hepatocellular carcinoma, fibrosis, and related disorders .
3
Research Areas:
Ezurpimtrostat (GNS561) is an orally active PPT1 inhibitor, autophagy inhibitor, immunomodulator, anti-inflammatory agent, and anticancer agent. Ezurpimtrostat inhibits PPT1, dysregulates lysosomal function, redistributes mTOR, and induces apoptosis. Ezurpimtrostat reduces IFN‑α, CRP, immune complex deposition, and SARS‑CoV‑2 viral load. Ezurpimtrostat can be used for the study of systemic lupus erythematosus, SARS‑CoV‑2, hepatocellular carcinoma, fibrosis, and related disorders .
1
1
1 Cited Publications
Cat. No.: HY-P72112
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CALR; FLJ26680; Calreticulin; CRP55; Calregulin; ERp60; CC1qR; HACBP; CALR1; Grp60; SSA; Epididymis Secretory Sperm Binding Protein Li 99n; CRT; Autoantigen Ro; RO; HEL-S-99n; Sicca Syndrome Antigen A (Autoantigen Ro; Calreticulin); CRTC; Endoplasmic Reti
Species:
Mouse
Source:
E. coli
Synonyms: oATP trisodium salt
Target:
Research Areas:
Oxidized ATP (oATP) trisodium salt is a broad-spectrum P2 receptor inhibitor. Oxidized ATP trisodium salt irreversibly antagonizes P2X7R activation. Oxidized ATP trisodium salt inhibits c-reactive protein (CRP)-induced NLRP3 inflammasome activation. Oxidized ATP trisodium salt can be used for research of atherosclerosis .
Cat. No.: HY-P1823
CAS No.: 147516-85-6
Research Areas:
Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Synonyms: PD-72953
Target:
Research Areas:
Gemcabene (PD-72953), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity .
Synonyms: ZGN-1061
Target:
Research Areas:
Aclimostat (ZGN-1061) is a methionine aminopeptidase 2 (MetAP2) inhibitor. Aclimostat exhibits anti-obesity, anti-diabetic and ovarian cancer-related activities, and does not readily distribute to the central nervous system. Aclimostat acts on the active site of MetAP2 via irreversible covalent binding, and blocks enzyme activity through interactions with His231 and His339. Aclimostat regulates gene expression, reduces fat mass, plasma glucose, insulin levels, LDL-C, hs-CRP and leptin levels, while increasing adiponectin levels. Aclimostat can be used in research related to type 2 diabetes, overweight, obesity and ovarian cancer .
Cat. No.: HY-113553
CAS No.: 102185-28-4
Synonyms: (p-Aminophenyl)phosphocholine; p-Aminophenylphosphorylcholine; 4-APPC
Target:
Research Areas:
4-Aminophenylphosphorylcholine ((p-Aminophenyl) phosphocholine; p-Aminophenylphosphorylcholine; 4-APPC) is a phosphatidylcholine derivative that serves as a coupling ligand and antigen probe. When conjugated with gold nanoclusters, the phosphocholine head epitope of 4-Aminophenylphosphorylcholine is specifically recognized by anti-Pc IgM and CRP. It can be covalently coupled to human serum albumin (HSA) or glutathione-protected gold nanoclusters (Au-GSH) via covalent chemistry, respectively. The 4-Aminophenylphosphorylcholine-HSA complex acts as an ELISA coating antigen for detecting endogenous anti-Pc IgM antibodies in plasma; 4-Aminophenylphosphorylcholine-modified Au-GSH can be used to construct an ultra-stealthy NIR-II fluorescent gold nanocluster probe for imaging-related studies in mouse breast cancer and colon cancer models .
Cat. No.: HY-P1824
CAS No.: 130348-99-1
Target:
Research Areas:
Cat. No.: HY-P1836
CAS No.: 130349-01-8
Target:
Research Areas:
Cat. No.: HY-153489
CAS No.: 827355-42-0
Synonyms: ISIS-CRPRx
Research Areas:
ISIS 329993 (ISIS-CRPRx) is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis
Cat. No.: HY-RS03195
Target:
Research Areas:
CRP Human Pre-designed siRNA Set A contains three designed siRNAs for CRP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23317
Target:
Research Areas:
Crp Rat Pre-designed siRNA Set A contains three designed siRNAs for Crp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-153489A
Synonyms: ISIS-CRPRx sodium
Research Areas:
ISIS 329993 sodium is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx sodium has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis
Cat. No.: HY-RS24216
Target:
Research Areas:
Prr4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Prr4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19183
Target:
Research Areas:
Crip2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Crip2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03258
Target:
Research Areas:
CSRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CSRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Synonyms: PD-72953 calcium
Target:
Research Areas:
Gemcabene calcium (PD-72953 calcium), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity .
Target:
Research Areas:
Metamizole (Dipyrone) hemimagnesium is an anti-inflammatory and antioxidant agent with the property of reducing body temperature. Metamizole hemimagnesium can decrease the levels of C-reactive protein (CRP) and interleukin 6 (IL-6). It is also an orally active cyclooxygenase (COX) inhibitor. Metamizole hemimagnesium can inhibit cell proliferation and promote apoptosis. It can be used in the research of inflammation and fever .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
