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Click Chemistry

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2488

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167

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133

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20

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54

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1896

Click Chemistry

143

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3

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-151835

    ADC Linker Others
    DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
    DBCO-PEG24-NHS ester
  • HY-151862

    ADC Linker Others
    3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    3-Azidopropylamine
  • HY-151656
    15-Azido-pentadecanoic acid
    2 Publications Verification

    Azido Palmitic Acid

    ADC Linker Others
    15-Azido-pentadecanoic acid is a click chemistry reagent containing an azide group. Azido Palmitic Acid can be used to identify and characterize post-translationally palmitylated proteins with using a simple and robust two-step labeling and detection technique . 15-Azido-pentadecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    15-Azido-pentadecanoic acid
  • HY-151685

    ADC Linker Others
    Kdo Azide is a click chemistry reagent containing an azide. Kdo Azide is a metabolic labeling reagent . Kdo Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Kdo Azide
  • HY-151840

    ADC Linker Others
    4-Azidobenzyl alcohol is a click chemistry reagent containing an azide group . 4-Azidobenzyl alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    4-Azidobenzyl alcohol
  • HY-151834

    ADC Linker Others
    DBCO-PEG2-DBCO is a click chemistry reagent containing a DBCO group. DBCO-PEG2-DBCO is a PEG linker containing two terminal DBCO groups. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. T Reagent grade, for research use only .
    DBCO-PEG2-DBCO
  • HY-W588725A
    N3-Cho bromide
    1 Publications Verification

    Azido-choline bromide

    Biochemical Assay Reagents Others
    N3-Cho (Azido-choline) bromide is a click chemistry reagent containing an azide group that can be used in the synthesis of cell membrane structures .
    N3-Cho bromide
  • HY-127112

    Drug Derivative Others
    Oleic acid alkyne is Oleic acid (HY-N1446) with an acetylene group. The terminal alkyne group can be used for click chemical ligation reactions. Oleic acid can be hydroxylated by a microsomal cytochrome P-450-dependent system (ω-OAH). Through click chemistry reactions, fluorescent or biotin-labeled oleic acid can be introduced to analyze its metabolism and biological activity.
    Oleic acid alkyne
  • HY-151817

    Biochemical Assay Reagents Others
    5-Azidomethyl-uridine is a click chemistry reagent containing an azide group. The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction.
    5-Azidomethyl-uridine
  • HY-151827

    ADC Linker Others
    DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
    DBCO-PEG2-NHS ester
  • HY-151698

    ADC Linker Others
    TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    TCO-NHS Ester (axial)
  • HY-W540978

    Biochemical Assay Reagents Others
    3-Azido-7-hydroxycoumarin is a click chemistry reagent containing an azido group. Under Cu (II) catalysis, it undergoes azide-alkyne cycloaddition (CuAAC) click reaction with 3-butyn-1-ol and emits a fluorescent signal .
    3-Azido-7-hydroxycoumarin
  • HY-151645

    ADC Linker Others
    Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .
    Alkyne-SNAP
  • HY-151819

    ADC Linker Others
    N3Ac-OPhOMe is a click chemistry reagent containing azido and p-methoxyphenyl ester groups, which can be used for biomolecule conjugation and organic synthesis .
    N3Ac-OPhOMe
  • HY-151727

    ADC Linker Others
    Norbornene-NHS is a norbornene-functionalized antibody-drug conjugate linker (ADC Linker) bearing an NHS ester, which is applicable for highly efficient and specific antibody conjugation reactions in ADC research and development. Norbornene-NHS also acts as an azide-group-containing click chemistry reagent, serving as a dienophile for copper-free click reaction conjugation .
    Norbornene-NHS
  • HY-D1070

    DNA Stain Others
    DBCO-PEG4-TAMRA is a PEG-based TAMRA dye and contains a DBCO group, which enables Click Chemistry. The TAMRA dye is a dye widely used in oligonucleotide labeling and automated DNA sequencing applications. DBCO-PEG4-TAMRA is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-PEG4-TAMRA
  • HY-151720
    Cy5.5 DBCO
    1 Publications Verification

    ADC Linker Others
    Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .
    Cy5.5 DBCO
  • HY-151688

    ADC Linker Others
    6-O-Propynyl-2'-deoxyguanosine is a click chemistry reagent containing an alkyne group. 6-O-Propynyl-2'-deoxyguanosine can be used for the research of various biochemical .
    6-O-Propynyl-2'-deoxyguanosine
  • HY-151669

    ADC Linker Others
    Fmoc-D-Aha-OH is a click chemistry reagent containing an azide . Fmoc-D-Aha-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Fmoc-D-Aha-OH
  • HY-151666

    Biochemical Assay Reagents Others
    6-Azido-D-lysine is a click chemistry reagent containing an azide . 6-Azido-D-lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    6-Azido-D-lysine
  • HY-151675

    Biochemical Assay Reagents Others
    H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide . H-L-Tyr(3-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    H-L-Tyr(3-N3)-OH
  • HY-151859

    Biochemical Assay Reagents Others
    N3-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group. N3-Gly-Gly-OH undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkyne group. N3-Gly-Gly-OH also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-Gly-Gly-Gly-OH can be used to construct peptide-like ADC linkers via click chemistry .
    N3-Gly-Gly-OH
  • HY-126458

    E3 ligase Ligand-Linker Conjugates 32

    E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is an E3 ligase ligand-linker conjugate. Thalidomide-O-PEG2-propargyl is also a click chemistry reagent containing an alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules bearing an azide group .
    Thalidomide-O-PEG2-propargyl
  • HY-151653

    O-Propargyl-D-tyrosine

    ADC Linker Others
    H-D-Tyr(Propargyl)-OH is a click chemistry reagent containing an Azide . H-D-Tyr(Propargyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    H-D-Tyr(Propargyl)-OH
  • HY-151666A

    Biochemical Assay Reagents Others
    6-Azido-D-lysine hydrochloride is a click chemistry reagent containing an azide . 6-Azido-D-lysine hydrochloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    6-Azido-D-lysine hydrochloride
  • HY-130544

    5-Azidovaleric acid

    Biochemical Assay Reagents PROTAC Linkers Others
    5-Azidopentanoic acid (5-Azidovaleric acid) is a organic acid that can be used in click chemistry reactions .
    5-Azidopentanoic acid
  • HY-W018008

    Ferrocenylacetylene; Ferrocenylethyne

    Biochemical Assay Reagents Others
    Ethynylferrocene (Ferrocenylacetylene) is a click chemistry agent. Ethynylferrocene can be used for labeling of hairpin DNA probes to monitor the DNA hybridization via the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) .
    Ethynylferrocene
  • HY-151748

    ADC Linker Others
    N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    N3-L-Orn(Fmoc)-OH
  • HY-151790

    ADC Linker Others
    Alkyne-SS-COOH is a click chemistry reagent containing an alkyne group. Alkyne-SS-COOH can be used for the research of various biochemical .
    Alkyne-SS-COOH
  • HY-15458A

    VEGFR Cancer
    (S)-SAR131675 is the S-enantiomer of SAR131675 (HY-15458), a potent and selective VEGFR3 inhibitor and a click chemistry reagent .
    (S)-SAR131675
  • HY-151771

    ADC Linker Others
    DACN(Tos,Mal) is a click chemistry reagent containing an azide. DACN(Tos,Mal) possess high thermal and chemical stability along with comparable click reactivity .
    DACN(Tos,Mal)
  • HY-151781

    ADC Linker Others
    Fmoc-L-Dap(Poc)-OH is a click chemistry reagent containing an azide group. Amino acid building block suitable for side chain Click conjugation with standard protocols and together with tetrazine linkers in copper-free Click conjugation (Diels-Alder) .
    Fmoc-L-Dap(Poc)-OH
  • HY-164416

    Drug Intermediate Inflammation/Immunology
    DBCO-Dextran sulfate (MW 40000) can be used to construct DS-EXOs in cells via click chemistry, that can be used for the research of rheumatoid arthritis (RA) .
    DBCO-Dextran sulfate (MW 40000)
  • HY-151742

    ADC Linker Others
    Norbornene-methyl-NHS is a norbornene-based antibody-drug conjugate linker (ADC Linker) bearing methyl and NHS ester functional groups, which can be used for specific antibody conjugation. Norbornene-methyl-NHS is also a click chemistry reagent containing a TCO group, acting as a dienophile for conjugation via the Diels-Alder reaction, namely the copper-free click reaction with tetrazine .
    Norbornene-methyl-NHS
  • HY-151814

    ADC Linker Others
    (2S,4S)-Fmoc-L-Pro(4-NHPoc)-OH is a click chemistry reagent containing an azide group.
    (2S,4S)-Fmoc-L-Pro(4-NHPoc)-OH
  • HY-151701

    Fluorescent Dye Others
    DiSulfo-Cy5 alkyne is a fluorescent dye can be used as a click chemistry reagent .
    DiSulfo-Cy5 alkyne
  • HY-151729

    ADC Linker Others
    N3-D-Dab(Boc)-OH is a click chemistry reagent containing an Azide . N3-D-Dab(Boc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    N3-D-Dab(Boc)-OH
  • HY-151733

    ADC Linker Others
    Fmoc-D-Dbu(N3)-OH is a click chemistry reagent containing an Azide . Fmoc-D-Dbu(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Fmoc-D-Dbu(N3)-OH
  • HY-W879040

    Biochemical Assay Reagents Others
    Sulfo-DBCO-NHS ester is a click chemistry reagent containing an azide group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. NHS ester can bind to amino acids or other molecules containing amino groups .
    Sulfo-DBCO-NHS ester
  • HY-151752

    ADC Linker Others
    Mal-AMCHC-N-Propargylamide is a click chemistry reagent containing an azide group. Mal-AMCHC-N-Propargylamide can be a bio-conjugation reagent for antibody-agent-conjugate synthesis using Click-Chemistry .
    Mal-AMCHC-N-Propargylamide
  • HY-151730

    ADC Linker Others
    (Me)Tz-butanoic acid is a click chemistry reagent containing an azide. (Me)Tz-butanoic acid is tetrazine linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with dienophiles . (Me)Tz-butanoic acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    (Me)Tz-butanoic acid
  • HY-108368A
    Azido-PEG2-CH2COOH (CHA)
    1 Publications Verification

    ADC Linker Others
    Azido-PEG2-CH2COOH (CHA) is a azido-modified PEG2 acid, can be used as a click chemistry reagent . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Azido-PEG2-CH2COOH (CHA)
  • HY-151643

    ADC Linker Others
    beta-Glc-TEG-Alkyne is a click chemistry reagent containing an alkynes group. beta-Glc-TEG-Alkyne can be used for the research of various biochemical .
    beta-Glc-TEG-Alkyne
  • HY-151684

    ADC Linker Others
    Boc-Ser(O-propargyl)-OH is a click chemistry reagent containing an alkynes group. Boc-Ser(O-propargyl)-OH can be used for the research of various biochemical .
    Boc-Ser(O-propargyl)-OH
  • HY-151745

    ADC Linker Others
    N3-TOTA-Suc is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments . N3-TOTA-Suc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    N3-TOTA-Suc
  • HY-151864

    ADC Linker Others
    DecarboxyBiotin-Alkyne is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
    DecarboxyBiotin-Alkyne
  • HY-D1625

    Fluorescent Dye Others
    Cy5 DBCO chloride is an azide reaction probe and the addition of DBCO molecules allows the imaging of azide-labelled biomolecules by a copper-free "Click Chemistry" reaction . Cy5 DBCO (chloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Cy5 DBCO chloride
  • HY-W051612A
    DL-Propargylglycine sodium
    2 Publications Verification

    Amino Acid Derivatives Biochemical Assay Reagents Others
    DL-Propargylglycine sodium is a Glycine (HY-Y0966) derivative. DL-Propargylglycine sodium is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    DL-Propargylglycine sodium
  • HY-151844

    ADC Linker Others
    2-Azido-adenosine is a click chemistry reagent containing an azide group . 2-Azido-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    2-Azido-adenosine
  • HY-151638

    ADC Linker Others
    FMOC-3-azido-D-alanine is a click chemistry reagent containing an azide group . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    FMOC-3-azido-D-alanine

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