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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
DC1
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "DC1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N2120
CAS No.: 88509-91-5
Category:
Iridaceae Flavonoids Other Diseases Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Isoflavones
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Cat. No.: HY-112899
CAS No.: 169901-27-3
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DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.
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DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.
Cat. No.: HY-145636
CAS No.: 2490556-51-7
Synonyms: AEX4089DC1; MGC018
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Vobramitamab duocarmazine (AEX4089DC1; MGC018), a humanized antibody-drug conjugate (ADC) targeted against B7-H3 (CD276). Vobramitamab duocarmazine is comprised of the cleavable linker-Duocarmycin payload, Vc-seco-DUBA (HY-128957), conjugated to an anti-B7-H3 humanized IgG1κ monoclonal antibody. Vobramitamab duocarmazine has antineoplastic activity [1].
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DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer agents (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component [1].
Cat. No.: HY-112901
CAS No.: 1354787-69-1
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DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer [1] .
Cat. No.: HY-112900
CAS No.: 1354787-71-5
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DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC50s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer [1] .
Cat. No.: HY-N8922
CAS No.: 66779-34-8
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Cat. No.: HY-P5743
CAS No.: 1443436-79-0
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Cat. No.: HY-P5744
CAS No.: 1443436-80-3
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Cat. No.: HY-P5743A
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Cat. No.: HY-N17338
CAS No.: 17812-38-3
Synonyms: (-)-Nupharamine
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Cat. No.: HY-N0057A
CAS No.: 89886-31-7
Synonyms: (E)-3,4-Di-O-caffeoylquinic acid; (E)-Isochlorogenic acid B
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Cat. No.: HY-P5162
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Cat. No.: HY-RS09610
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NT5DC1 Human Pre-designed siRNA Set A contains three designed siRNAs for NT5DC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P5744A
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Cat. No.: HY-N11032
CAS No.: 83287-02-9
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Cat. No.: HY-N11029
CAS No.: 88142-60-3
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Cat. No.: HY-N8999
CAS No.: 33954-34-6
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Cat. No.: HY-N1303
CAS No.: 21671-00-1
Synonyms: Shoric acid
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
