40 Results for "

Firefly

" in MedChemExpress (MCE) Product Catalog:
Products (40)

40 Results for "Firefly" in MCE Product Catalog:

112
D-Luciferin potassium
D-Luciferin potassium
0 Images
112 Publications Verification
Cat. No.: HY-12591B
CAS No.: 115144-35-9
Purity:  99.97%
Synonyms: D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium
D-luciferin potassium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
112
D-Luciferin sodium
D-Luciferin sodium
0 Images
112 Publications Verification
Cat. No.: HY-12591
CAS No.: 103404-75-7
Purity:  99.92%
Synonyms: D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium
D-luciferin sodium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
112
D-Luciferin
D-Luciferin
0 Images
112 Publications Verification
Cat. No.: HY-12591A
CAS No.: 2591-17-5
Purity:  99.54%
Synonyms: D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
Category:  

Natural Products Animals Other Diseases Disease Research Fields

Target:  

Fluorescent Dye

D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
32
Renilla-Firefly Luciferase Dual Assay Kit
Renilla-Firefly Luciferase Dual Assay Kit
0 Images
32 Cited Publications
Cat. No.: HY-K1013

MCE Renilla-Firefly Luciferase Dual Assay Kit is designed to be used for high-throughput, rapid quantitation of both Firefly and Renilla luciferases from a single sample in mammalian cell culture.

11
YAP/TAZ inhibitor-1
YAP/TAZ inhibitor-1
0 Images
11 Cited Publications
Cat. No.: HY-111429
CAS No.: 2093565-23-0
Purity:  99.72%
Target:  

YAP

Research Areas:  

Cancer

YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor extracted from patent WO2017058716A1, Compound 1, has an IC50 of <0.100 μΜ in firefly luciferase assay .
7
AkaLumine hydrochloride
AkaLumine hydrochloride
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7 Cited Publications
Cat. No.: HY-112641A
CAS No.: 2558205-28-8
Purity:  99.92%
AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
1
Firefly luciferase mRNA-LNP
Firefly luciferase mRNA-LNP
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1 Cited Publications
Cat. No.: HY-153229
Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency .
Luciferase, firefly
Luciferase, firefly
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Cat. No.: HY-P1004A
CAS No.: 61970-00-1
Target:  

Fluorescent Dye

Research Areas:  

Others

Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Luciferase, firefly catalytic substrate is D-luciferin (HY-12591B) .
Firefly Luciferase mRNA(N1-Me-Pseudo UTP)
Firefly Luciferase mRNA(N1-Me-Pseudo UTP)
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Cat. No.: HY-153080
Purity:  94.6%
Target:  

Fluorescent Dye mRNA

Research Areas:  

Others

Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a modified form of firefly luciferase mRNA, which is N1-methylated pseudo uridine (N1-Me-Pseudo UTP). Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a commonly used reporter molecule in biomedical and mRNA research and its core function is to rapidly and quantitatively monitor the expression and delivery efficiency of mRNA through the emission of light signals .
Firefly luciferase-IN-1
Firefly luciferase-IN-1
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Cat. No.: HY-155945
CAS No.: 2765796-41-4
Purity:  98.70%
Target:  

Reactive Oxygen Species (ROS)

Research Areas:  

Others

Firefly luciferase-IN-1 (compound 48) is a highly potent and reversible inhibitor of firefly luciferase with an IC50 value of 0.25 nM .
DMG-pSar25
DMG-pSar25
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Cat. No.: HY-N16040
CAS No.: 2936622-30-7
Category:  

Lipid

Target:  

Liposome

DMG-pSar25 is a double lipid-tailed polysarcosine lipid with 25 sarcosine moieties, serving as a PEG lipid substitute in lipid nanoparticle formulations for mRNA delivery. DMG-pSar25 supports mRNA delivery in lipid nanoparticle formulations .
NR2F6 modulator-1
NR2F6 modulator-1
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Cat. No.: HY-147228
CAS No.: 904449-84-9
Purity:  99.74%
Target:  

Orphan Nuclear Receptor

Research Areas:  

Inflammation/Immunology Cancer

NR2F6 modulator-1 is a NR2F6 modulator. NR2F6 modulator-1 is applicable for immunoregulation and tumor research .
Firefly luciferase mRNA (5moU)
Firefly luciferase mRNA (5moU)
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Cat. No.: HY-174493
Target:  

mRNA

Research Areas:  

Others

Firefly luciferase (FLuc) mRNA (5moU) expresses a luciferase protein, originally isolated from the firefly, Photinus pyralis. FLuc is commonly used in mammalian cell culture to measure both gene expression and cell viability. It emits bioluminescence in the presence of the substrate, luciferin.
Firefly Luciferase mRNA
Firefly Luciferase mRNA
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Cat. No.: HY-174790
Target:  

mRNA

Research Areas:  

Cancer

Firefly Luciferase mRNA is a reporter mRNA that can be transfected into cells to express firefly luciferase protein. Firefly Luciferase mRNA induces cytotoxicity in cancer cells at low concentrations. In cancer cells, the expression level of luciferase shows a non-linear relationship with the dose of Firefly Luciferase mRNA. When combined with the H2S-responsive bioluminescent probe (H-Luc), Firefly Luciferase mRNA enables bioluminescence-based detection of endogenous hydrogen sulfide in non-transgenic NAFLD cell models and NAFLD mouse models. Firefly Luciferase mRNA can be used in studies related to non-alcoholic fatty liver disease .
Mycaminosyltylonolide
Mycaminosyltylonolide
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Cat. No.: HY-N11422
CAS No.: 61257-02-1
Category:  

Microorganisms Antibiotics Disease Research Antibacterial

Target:  

Antibiotic Bacterial

Mycaminosyltylonolide is a potent antibiotic. Mycaminosyltylonolide shows antibacterial activity. Mycaminosyltylonolide inhibits luciferase synthesis .
Firefly Luciferase circRNA
Firefly Luciferase circRNA
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Cat. No.: HY-153082
Target:  

Fluorescent Dye

Research Areas:  

Others

Firefly Luciferase circRNA will express a luciferase protein, originally isolated from the Photinus pyralis (Firefly). Firefly Luciferase circRNA is ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.
Firefly luciferase-IN-2
Firefly luciferase-IN-2
0 Images
Cat. No.: HY-160869
CAS No.: 796108-95-7
Target:  

Fluorescent Dye

Research Areas:  

Others

Firefly luciferase-IN-2 (compound 5j) is an inhibitor of ATP-dependent luciferase (Firefly luciferase), the major light-emitting enzyme in fireflies and kowtow bugs. Firefly luciferase-IN-2 inhibits P. pyralis luciferase with an IC50 of 0.15 μM, while the inhibitory potency against R. reniformis is not significant .
Firefly luciferase-IN-3
Firefly luciferase-IN-3
0 Images
Cat. No.: HY-160870
CAS No.: 898155-17-4
Target:  

Fluorescent Dye

Research Areas:  

Others

Firefly luciferase-IN-3 (CID: 17087944) is an inhibitor of ATP-dependent luciferase (Firefly luciferase) and has nM-level inhibitory activity against NanoLuc (pIC50=7.5) .
Firefly luciferase-IN-5
Firefly luciferase-IN-5
0 Images
Cat. No.: HY-160873
CAS No.: 959557-37-0
Target:  

Fluorescent Dye

Research Areas:  

Others

Firefly luciferase-IN-5 (CID: 16031203) is an inhibitor of ATP-dependent luciferase (Firefly luciferase). It has nM-level inhibitory activity against GRLuc, RLuc8, and RLuc respectively (pIC50=8.5,7.5,5.5) .
Fluc-IN-1
Fluc-IN-1
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Cat. No.: HY-170496
CAS No.: 2940242-10-2
Target:  

Wnt

Research Areas:  

Cancer

Fluc-IN-1 (Compound 3) is an inhibitor for firefly luciferase with an IC50 of 25 nM. Fluc-IN-1 inhibits WNT/β-catenin signaling pathway with an IC50 of 33 nM (measuring by TOPFlash assay) .
Assay Types