17 Results for "

GLO1

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "GLO1" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-136684
CAS No.: 166038-00-2
Purity:  99.00%
Synonyms: S-p-Bromobenzylglutathione cyclopentyl diester
Target:  

Glyoxalase (GLO)

Research Areas:  

Neurological Disease Cancer

BrBzGCp2 is a Glyoxalase 1 (GLO1) inhibitor, with a GC50 of 4.23 μM in HL-60 cells. BrBzGCp2 possesses antitumor and neuroprotective activity [1] .
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Cat. No.: HY-RS05486
Research Areas:  

Others

Glo1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Glo1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS05485
Research Areas:  

Others

GLO1 Human Pre-designed siRNA Set A contains three designed siRNAs for GLO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS05487
Research Areas:  

Others

Glo1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Glo1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-185057
CAS No.: 41656-56-8
Synonyms: S-Lactylglutathione; (R)-S-Lactoylglutathione
S-D-Lactoylglutathione is a crucial intermediate metabolite of the glyoxalase (Glo) system. S-D-Lactoylglutathione acts as a "bridge molecule" for the conversion of methylglyoxal (MGO) into non-toxic D-lactic acid by continuous catalysis from Glo1 to Glo2, preventing cell damage caused by the accumulation of MGO [1].
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Cat. No.: HY-124824
CAS No.: 700870-56-0
Target:  

Glyoxalase (GLO)

Research Areas:  

Others

Methyl gerfelin inhibits osteoclast differentiation by binding 3 major cellular proteins: glyoxalase 1 (GLO1), sterol binding protein 2 (SCP2), and small glutamine-rich tetratricopeptide repeat containing protein A (SGTA). Methyl gerfelin is a potent GLO1 inhibitor related to the flavonoid class [1] .
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Cat. No.: HY-146657
CAS No.: 828262-76-6
Target:  

Glyoxalase (GLO)

Research Areas:  

Cancer

4BAB (compound 29) is an irreversible glyoxalase I (GLO1) inhibitor. 4BAB has anticancer effects [1].
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Cat. No.: HY-146653
CAS No.: 1622952-07-1
Target:  

Glyoxalase (GLO)

Research Areas:  

Cancer

Glyoxalase I inhibitor 1 (compound 23) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 26 nM [1]. Glyoxalase I inhibitor 1 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-W001288
CAS No.: 1074-86-8
Indole-4-carboxaldehyde is an ergot alkaloid precursor that regulates glycosylation and inflammation. Indole-4-carboxaldehyde upregulates Glo-1, inhibits MGO-induced NF-κB activation, and suppresses MGO-induced expression of TNF-α and IFN-γ. Indole-4-carboxaldehyde inhibits MGO-induced formation of advanced glycation end products (AGE) and expression of their receptor (RAGE). Indole-4-carboxaldehyde is a core metabolite produced in the pedicels of Summer Black grapes after exogenous gibberellin treatment, and it directly promotes fruit enlargement and fruit set of Summer Black grapes. Indole-4-carboxaldehyde can be used in studies related to hepatic steatosis and plant growth regulation [1] .
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Cat. No.: HY-146654
CAS No.: 2314467-61-1
Target:  

Glyoxalase (GLO)

Research Areas:  

Cancer

Glyoxalase I inhibitor 2 (compound 26) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 0.5 µM. Glyoxalase I inhibitor 2 has the potential for the research of depression and anxiety [1].
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Cat. No.: HY-146655
CAS No.: 1415388-25-8
Purity:  98.06%
Target:  

Glyoxalase (GLO)

Research Areas:  

Cancer

Glyoxalase I inhibitor 3 (compound 22g) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 0.011 µM. Glyoxalase I inhibitor 3 has the potential for the research of depression and anxiety [1].
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Cat. No.: HY-34005
CAS No.: 3743-22-4
Target:  

Glyoxalase (GLO)

Research Areas:  

Others

2-Dimethylaminophenol is an inhibitor of human glyoxalase 1 (GLO1). 2-Dimethylaminophenol disrupts metal binding by substituting the pyridine nitrogen donor with a dimethylamino group [1].
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Cat. No.: HY-P80942
Synonyms: Aldoketomutase; GLO1; GLOD1; Glx I; GLYI

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P88033

Host:  

Rabbit

Application:  

WB, FC, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-P810419
Synonyms: Aldoketomutase, GLO1, GLOD1, Glx I, GLYI, glyoxalase domain containing 1, Glyoxalase I, Ketone aldehyde mutase, Ketone-aldehyde mutase, Lactoyl glutathione lyase

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-W001288S
Indole-4-carboxaldehyde- 13C is the 13C-labeled Indole-4-carboxaldehyde (HY-W001288). Indole-4-carboxaldehyde is an ergot alkaloid precursor that regulates glycosylation and inflammation. Indole-4-carboxaldehyde upregulates Glo-1, inhibits MGO-induced NF-κB activation, and suppresses MGO-induced expression of TNF-α and IFN-γ. Indole-4-carboxaldehyde inhibits MGO-induced formation of advanced glycation end products (AGE) and expression of their receptor (RAGE). Indole-4-carboxaldehyde is a core metabolite produced in the pedicels of Summer Black grapes after exogenous gibberellin treatment, and it directly promotes fruit enlargement and fruit set of Summer Black grapes. Indole-4-carboxaldehyde can be used in studies related to hepatic steatosis and plant growth regulation [1] .
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Cat. No.: HY-P75162
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lactoylglutathione lyase; Glyoxalase I; Glx I
Species:  
Source:  
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