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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
Glibenclamide
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "Glibenclamide" in MCE Product Catalog:
28
28 Publications Verification
Synonyms: Glyburide
Research Areas:
Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel (KATP) inhibitor and can be used for the research of diabetes and obesity . Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR) . Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability . Glibenclamide can induce autophagy .
8
8 Cited Publications
Cat. No.: HY-D1297
CAS No.: 730931-46-1
5
5 Cited Publications
Cat. No.: HY-D1431
1
Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:
Research Areas:
Cat. No.: HY-D1429
CAS No.: 287715-95-1
Research Areas:
Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions .
Synonyms: Glyburide-d3
Cat. No.: HY-DY1074
CAS No.: 287715-95-1
Solvent and concentration: DMSO: 1 mM
Cat. No.: HY-15206S
CAS No.: 1189985-02-1
Cat. No.: HY-DY1043
CAS No.: 730931-46-1
Solvent and concentration: DMSO: 1 mM
Cat. No.: HY-DY1026
Solvent and concentration: DMSO: 1 mM
Cat. No.: HY-15206A
CAS No.: 52169-36-5
Synonyms: Glyburide potassium
Target:
Research Areas:
Glibenclamide (Glyburide) potassium is a potassium salt of Glibenclamide (HY-15206). Glibenclamid potassium exists in anhydrous and hydrate forms, with higher solubility compared to pure Glibenclamide .
Cat. No.: HY-117160
CAS No.: 23155-00-2
Synonyms: 4-trans-hydroxycyclohexyl Glyburide; 4-trans-hydroxy Glibenclamide
Target:
Research Areas:
rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide (HY-15206). It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9. rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/Kir6.2 with IC50 values of 0.95 and 100 nM, respectively.
Cat. No.: HY-15206R
CAS No.: 10238-21-8
Synonyms: Glyburide (Standard)
Target:
Mitochondrial Metabolism Autophagy CFTR P-glycoprotein Potassium Channel Reference Standards
Research Areas:
Glibenclamide (Standard) is the analytical standard of Glibenclamide. This product is intended for research and analytical applications. Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel (KATP) inhibitor and can be used for the research of diabetes and obesity . Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR) . Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability . Glibenclamide can induce autophagy .
Cat. No.: HY-117160S1
Cat. No.: HY-P11293
CAS No.: 1309855-53-5
Target:
Research Areas:
Cat. No.: HY-P4757
CAS No.: 108081-77-2
Cat. No.: HY-P1321
CAS No.: 158859-98-4
Synonyms: 1229U91; GW1229
Target:
Research Areas:
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
