2. Membrane Transporter/Ion Channel
  3. Potassium Channel CFTR
  4. Glibenclamide potassium

Glibenclamide potassium  (Synonyms: Glyburide potassium)

Cat. No.: HY-15206A
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Glibenclamide (Glyburide) potassium is a potassium salt of Glibenclamide (HY-15206). Glibenclamid potassium exists in anhydrous and hydrate forms, with higher solubility compared to pure Glibenclamide.

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CAS No. : 52169-36-5

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Glibenclamide potassium Related Antibodies

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IHC

    Glibenclamide potassium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jan 31;16(1):1212.  [Abstract]

    Immunoblots of DARTS assay that verified the binding of glyburide (50 µM, 24 h) to IFI16 in U251 cells (n = 3). An unpaired two-tailed t-test was applied. Data are presented as mean ± SD.

    Glibenclamide potassium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jan 31;16(1):1212.  [Abstract]

    Time response of the mice weight after implantation of U251R cells, on average, the xenograft was locally irradiated with 15 Gy of X-rays, and the mice were administered intragastrically with 1 mg/kg glyburide 2 h before irradiation (N = 5 per group). Data are presented as mean ± SD.

    Glibenclamide potassium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jan 31;16(1):1212.  [Abstract]

    Representative MRI images of U251R xenografts by T2-weighted MRI at 10-day and 20-day after cell implantation, the whole mount HE-stained brain sections of mice (administered intragastrically with 1 mg/kg glyburide 2 h before irradiation).

    Glibenclamide potassium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jan 31;16(1):1212.  [Abstract]

    Glyburide (administered intragastrically with 1 mg/kg glyburide 2 h before irradiation). The positive area of IFI16, HMOX1, and GPX4 in the U251R tumor tissues (N = 5 per group). An unpaired two-tailed t-test was applied. Data are presented as mean ± SD. “n” means the number of individual experiments. “N” represents the number of mice analyzed.

    Glibenclamide potassium purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2020 Mar;153:104679.  [Abstract]

    Glucose-dependent insulinotropic effects of CPU025 in MIN6 cells. MIN6 cells were treated with 2 or 25 mM glucose in the absence or presence of Glibenclamide (3 μM).

    Glibenclamide potassium purchased from MedChemExpress. Usage Cited in: Front Cell Dev Biol. 2020 May 12;8:269.  [Abstract]

    The inhibition of HSP70 releasing by Glibenclamide suppresses morphine-induced ER stress and the phosphorylation of PKA and NR-1. Glibenclamide (200 μM) inhibits the decrease of intracellular HSP70 caused by morphine in SH-SY5Y cells.

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    Description

    Glibenclamide (Glyburide) potassium is a potassium salt of Glibenclamide (HY-15206). Glibenclamid potassium exists in anhydrous and hydrate forms, with higher solubility compared to pure Glibenclamide[1].

    Clinical Trial
    Molecular Weight

    532.09

    Formula

    C23H27ClKN3O5S
    CAS No.
    SMILES

    O=C([N-]CCC1=CC=C(S(=O)(NC(NC2CCCCC2)=O)=O)C=C1)C3=CC(Cl)=CC=C3OC.[K+]
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
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    Glibenclamide potassium Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Glibenclamide52169-36-5GlyburidePotassium ChannelCFTRKcsACystic fibrosis transmembrane conductance regulatorInhibitorinhibitorinhibit

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