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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
GnRH-R
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "GnRH-R" in MCE Product Catalog:
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BAY-784 is a gonadotropin releasing hormone receptor (GnRH-R) antagonist probe with IC50s of 21 and 24 nM for human and rat GnRH-R, respectively .
Cat. No.: HY-W041308
CAS No.: 64359-81-5
Synonyms: Kathon 930
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DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR)-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca 2+ signaling cascades .
Cat. No.: HY-178419
CAS No.: 666852-12-6
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GnRH-R antagonist-3 (Compound 37) is a Gonadotropin releasing hormone receptor (GnRH-R) antagonist with IC50s of 94 and 275 nM for rat and human GnRH-R, respectively. GnRH-R antagonist-3 can be used for hormone dependent diseases such as endometriosis, breast and prostate cancer research .
Cat. No.: HY-151247
CAS No.: 2826273-90-7
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GnRH-R antagonist 1 (compound 21a) is an orally safe and membrane-permeable GnRH-R antagonist with high binding affinity (IC50=0.57 nM) and potent in vitro antagonistic activity (IC50=2.18 nM). GnRH-R antagonist 1 can be used in studies of advanced prostate cancer and premature LH peaks preventing .
Cat. No.: HY-178418
CAS No.: 1000819-21-5
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GnRH-R antagonist-2 (Compound 44c) is a Gonadotropin releasing hormone receptor (GnRH-R) antagonist with IC50s of 43 and 88 nM for rat and human GnRH-R, respectively. GnRH-R antagonist-2 can be used for hormone dependent diseases such as endometriosis, breast and prostate cancer research .
Cat. No.: HY-12096
CAS No.: 872002-72-7
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WAY-207024 is an orally active gonadotropin releasing hormone receptor (GnRH-R) antagonist (human GnRH: IC50 of 12 nM, rat GnRH: IC50 of 71 nM). WAY-207024 inhibits rat LH release with an IC50 of 350 nM. WAY-207024 lowers rat plasma leuteinizing hormone (LH) levels after oral administration .
Cat. No.: HY-16168B
CAS No.: 934246-14-7
Synonyms: FE 200486 acetate hydrate
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Cat. No.: HY-12096A
CAS No.: 872002-73-8
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WAY-207024 dihydrochloride is an orally active gonadotropin releasing hormone receptor (GnRH-R) antagonist (human GnRH: IC50 of 12 nM, rat GnRH: IC50 of 71 nM). WAY-207024 dihydrochloride inhibits rat LH release with an IC50 of 350 nM. WAY-207024 dihydrochloride lowers rat plasma leuteinizing hormone (LH) levels after oral administration .
Cat. No.: HY-W041308R
CAS No.: 64359-81-5
Synonyms: Kathon 930 (Standard)
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DCOIT (Standard) is the analytical standard of DCOIT. This product is intended for research and analytical applications. DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR)-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca2+ signaling cascades[1].
Cat. No.: HY-P11265
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Cat. No.: HY-RS05578
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GNRHR Human Pre-designed siRNA Set A contains three designed siRNAs for GNRHR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05579
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Gnrhr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gnrhr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05580
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Gnrhr Rat Pre-designed siRNA Set A contains three designed siRNAs for Gnrhr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-117982
CAS No.: 1308378-95-1
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SKI2496 is an orally active GnRH receptor antagonist (IC50: 0.25 nM for hGnRHR, 13.2 nM for monkey GnRHR, 279.2 nM for rat GnRHR). SKI2496 blocks Ca 2+ flux with an IC50 value of 0.76 nM. SKI2496 inhibits ERK1/2 phosphorylation with an IC50 value of 2.6 nM. SKI2496 inhbits serum LH concentrations, and can be used for research of sex hormone-dependent disorders .
Cat. No.: HY-14369R
CAS No.: 832720-36-2
Synonyms: NBI-56418 sodium (Standard)
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Elagolix sodium (Standard) is the analytical standard of Elagolix sodium. This product is intended for research and analytical applications. Elagolix sodium is a human GnRH receptor (GnRHR) antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.
Cat. No.: HY-16168AS
Synonyms: FE 200486-d7 free base
Cat. No.: HY-P0009S1
Synonyms: SB-75-d10
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
