Search Result

Results for "

Heat shock protein

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HSP (83) AAK1 (1) Akt (3) AMPK (1) Antibiotic (4) Apoptosis (24) Autophagy (13) Bacterial (11) Bcl-2 Family (1) c-Kit (1) Caspase (2) CDK (6) Cyclin G-associated Kinase (GAK) (2) DNA/RNA Synthesis (6) Drug Isomer (1) Drug Metabolite (2) Endogenous Metabolite (3) Enterovirus (1) Environmental Pollutants (2) ERK (4) Estrogen Receptor/ERR (1) Eukaryotic Initiation Factor (eIF) (1) Ferroptosis (2) Fluorescent Dye (1) Fungal (1) Glutathione S-transferase (1) GSK-3 (1) HBV (1) HCV (1) HDAC (3) Hedgehog (1) Heme Oxygenase (HO) (1) HIF/HIF Prolyl-Hydroxylase (1) HMG-CoA Reductase (HMGCR) (10) Influenza Virus (1) Integrin (1) Interleukin Related (2) IRE1 (1) Isotope-Labeled Compounds (2) JAK (1) JNK (5) LIM Kinase (LIMK) (1) Liposome (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) MMP (1) Monoamine Oxidase (1) mTOR (2) Na+/K+ ATPase (1) NF-κB (1) Orthopoxvirus (3) P-glycoprotein (1) p38 MAPK (6) Parasite (2) PARP (1) Peptide-Drug Conjugates (PDCs) (1) PERK (1) PI3K (1) Potassium Channel (13) PROTACs (1) Raf (1) Ras (1) Reactive Oxygen Species (ROS) (6) Reference Standards (15) RIP kinase (1) Salt-inducible Kinase (SIK) (1) SnRK (1) STAT (3) TNF Receptor (2) Toll-like Receptor (TLR) (1) TrxR (1) Tyrosinase (1) ULK (1) Wee1 (1) YAP (1) β-catenin (1)
By Research Areas:	Cancer (83) Cardiovascular Disease (16) Infection (14) Inflammation/Immunology (17) Metabolic Disease (21) Neurological Disease (21)
Oligonucleotides:	Phospholipids (1)

117

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: HSP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0293

Paeoniflorin Maximum Cited Publications 38 Publications Verification Peoniflorin	HSP	Infection Neurological Disease Cancer
Paeoniflorin is a **heat shock protein**-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .

HY-17504

Rosuvastatin Calcium 20+ Cited Publications Rosuvastatin hemicalcium; ZD 4522 Calcium	HMG-CoA Reductase (HMGCR) Autophagy Potassium Channel Bacterial	Cardiovascular Disease Metabolic Disease Cancer
Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC₅₀ of 195 nM . Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

HY-15205

Ganetespib Maximum Cited Publications 42 Publications Verification STA-9090	HSP Apoptosis	Cancer
Ganetespib (STA-9090) is a heat shock protein 90 (HSP90) inhibitor which exhibits potent cytotoxicity in a wide variety of hematological and solid tumor cell lines. Ganetespib has antiangiogenic effects in colorectal cancer mediated through inhibition of HIF-1α and STAT3 .

HY-B0425

Novobiocin 10+ Cited Publications Albamycin; Cathomycin	Antibiotic DNA/RNA Synthesis HSP Apoptosis Bacterial Orthopoxvirus	Infection Cancer
Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity .

HY-B0425A

Novobiocin sodium 10+ Cited Publications Albamycin sodium; Cathomycin sodium	Bacterial Antibiotic Orthopoxvirus Apoptosis DNA/RNA Synthesis HSP	Infection Cancer
Novobiocin (Albamycin) sodium is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity .

HY-17504A

Rosuvastatin 20+ Cited Publications ZD 4522	HMG-CoA Reductase (HMGCR) Autophagy Potassium Channel Bacterial	Cardiovascular Disease Metabolic Disease Cancer
Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC₅₀ of 11 nM. Rosuvastatin potently blocks hERG current with an IC₅₀ of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

HY-W014102

L-Alanyl-L-glutamine 1 Publications Verification	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations .

HY-D1063

IR-780 5+ Cited Publications	Fluorescent Dye Apoptosis Reactive Oxygen Species (ROS)	Cancer
IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .

HY-106443A

Arimoclomol maleate 5 Publications Verification BRX-220	HSP	Neurological Disease Metabolic Disease Inflammation/Immunology
Arimoclomol maleate (BRX-220) is an orally active co-inducer of heat shock proteins (HSP) . Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system .Arimoclomol maleate can be used for the study of Niemann–Pick disease type C.

HY-14463

Onalespib 10+ Cited Publications AT13387	HSP	Cancer
Onalespib (AT13387) is a potent and cross the blood-brain barrier heat-shock-protein-90 (Hsp90) inhibitor. Onalespib inhibits the proliferation, survival and migration. Onalespib decreases the expression of EGFR, p-EGFR, AKT, P-AKT, ERK1/2, P-ERK1/2, S6, P-S6 protein. Onalespib shows antitumor activity. Onalespib has the potential for the research of non-small cell lung cancer (NSCLC) .

HY-139214

IXA4 5+ Cited Publications	IRE1	Neurological Disease
IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation .

HY-17504B

Rosuvastatin Sodium 20+ Cited Publications ZD 4522 Sodium; X-Plended Sodium; Crestor Sodium	HMG-CoA Reductase (HMGCR) Potassium Channel Autophagy Bacterial	Cardiovascular Disease Metabolic Disease Cancer
Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC₅₀ of 195 nM . Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

HY-N6769

Radicicol 4 Publications Verification Monorden	HSP Bacterial Antibiotic Parasite	Infection
Radicicol is an inhibitor of Hsp90 with an IC₅₀ value < 1 μM, and leads to proteasomal degradation . Radicicol exhibits inhibition on PDK with IC₅₀s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB . Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC₅₀ value of 16.04 μM .

HY-18669

ML346 5+ Cited Publications	HSP	Cancer
ML346 is an activator of Hsp70 expression and HSF-1 activity, with an EC₅₀ of 4.6 μM for Hsp70. ML346 restores protein folding in conformational disease models, without significant cytotoxicity or lack of specificity. ML346 induces specific increases in genes and protein effectors of the heat shock response (HSR), including chaperones such as Hsp70, Hsp40, and Hsp27 .

HY-100110

KNK437 5+ Cited Publications Heat shock protein Inhibitor I	HSP	Cancer
KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40.

HY-106443

Arimoclomol 5 Publications Verification BRX-220 free base	HSP	Neurological Disease Metabolic Disease Inflammation/Immunology
Arimoclomol (BRX-220 free base) is an orally active co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.Arimoclomol can be used for the study of Niemann–Pick disease type C. Arimoclomol can cross the blood-brain barrier and can be used in research on Niemann-Pick disease type C .

HY-B0779

Teprenone 5 Publications Verification Geranylgeranylacetone	HSP	Neurological Disease Cancer
Teprenone is an anti-ulcer agent, and works as an inducer of heat shock proteins (HSPs).

HY-101712

TRC051384 5+ Cited Publications	HSP	Neurological Disease
TRC051384 is a potent inducer of heat shock protein 70 (HSP70). TRC051384 exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 can be used for the research of ischemic stroke .

HY-117282

JG-98 10+ Cited Publications	HSP Apoptosis	Cancer
JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages .

HY-106443B

Arimoclomol citrate 5 Publications Verification BRX-220 citrate	HSP	Neurological Disease Metabolic Disease Inflammation/Immunology
Arimoclomol citrate (BRX-220 citrate) is an orally active co-inducer of heat shock proteins (HSP) . Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system . Arimoclomol citrate can be used for the study of Niemann–Pick disease type C.

HY-107553

Chetomin 1 Publications Verification	HSP Apoptosis	Cancer
Chetomin, an active component of Chaetomium globosum, is a heat shock protein 90/hypoxia-inducible factor 1 alpha (Hsp90/HIF1α) pathway inhibitor. Chetomin is a potent, nontoxic non-small cell lung cancer cancer stem cells (NSCLC CSC)-targeting molecule .

HY-N7085

Citropten 5,7-Dimethoxycoumarin; Limettin	Environmental Pollutants ERK p38 MAPK JNK	Neurological Disease Inflammation/Immunology Cancer
Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through **heat shock protein-70, monoamine oxidase-A** and inhibition of apoptosis .

HY-125974

HM03 4 Publications Verification	HSP	Cancer
HM03 is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 has anticancer activity .

HY-B1425

Ethoxyquin	Environmental Pollutants Reactive Oxygen Species (ROS) HSP	Cancer
Ethoxyquin is an antioxidant which has been used in animal feed for many years and also an inhibitor of heat shock protein 90 (Hsp90).

HY-N2815

Ursolic acid acetate Acetylursolic acid; 3-Acetylursolic acid	Parasite HSP	Infection Cancer
Ursolic acid acetate (Acetylursolic acid) is a triterpenoid compound and an inhibitor of Plasmodium falciparum heat shock protein 90 (PfHsp90) with a K_D of 8.16 μM. Ursolic acid acetate is cytotoxic to KB cells, with an IC₅₀ value of 8.4 μM. Ursolic acid acetate can be used in tumor and antimalarial research .

HY-124611

JG-231	HSP Apoptosis	Cancer
JG-231 is an allosteric inhibitor of heat shock protein 70 (Hsp70). JG - 231 inhibits the binding of Hsp70 and BAG family proteins, including inhibition of Hsp70 and BAG1 with a K_i of 0.11 μM. JG-231 inhibits proliferation of tumor cells and induces apoptosis. JG-231 has antitumor activity .

HY-107599

AEG3482	JNK Apoptosis	Neurological Disease
AEG3482 is a potent antiapoptotic compound that inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25 .

HY-U00398

Bimoclomol	HSP	Cardiovascular Disease
Bimoclomol is a heat shock protein (HSP) coinducer, used for treatment of cardiovascular diseases.

HY-171616

DCEM1	HSP β-catenin	Cancer
DCEM1 binds to heat shock protein 60 (HSP60) and inhibits the interaction of HSP60 with ClpP, thereby blocking the mitochondrial unfolded protein response. DCEM1 inhibits β-catenin expression and ATP production in PC-3 and TKO cells. DCEM1 can be used in prostate cancer research .

HY-W015445

SD-169	p38 MAPK	Metabolic Disease
SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC₅₀ of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC₅₀ of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation .

HY-118487

OB-24 2 Publications Verification	Heme Oxygenase (HO) Reactive Oxygen Species (ROS)	Cancer
OB-24 is a selective small-molecule HO-1 inhibitor (IC₅₀ = 1.9 μM for HO-1 and IC₅₀ for HO-2 >100 μM). OB-24 possesses anti-tumor and anti-metastatic properties. OB-24 can be studies in research such as prostate cancer, melanoma, ovarian carcinoma and lung metastasis .

HY-142980

DOPG Dioleoylphosphatidylglycerol	Liposome	Inflammation/Immunology
DOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion .

HY-13479

EC144	HSP	Cancer
EC144 is a potent and selective inhibitor of heat shock protein 90 (Hsp90) with an IC₅₀ of 1.1 nM. EC144 inhibits tumor growth and causes partial tumor regressions. EC144 has the potential for the research of cancer diseases . EC144 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-12622

HSP70-IN-1 1 Publications Verification	HSP	Cancer
HSP70-IN-1 is a heat shock protein (HSP) inhibitor; inhibits the growth of Kasumi-1 cells with an IC₅₀ of 2.3 μM.

HY-149891

HSP90-IN-23	HSP	Cancer
HSP90-IN-23 (Comp 12-1) is an inhibitor of heat shock protein 90(HSP90) with an IC₅₀ of 9 nM. HSP90-IN-23 induces apoptosis of tumor cells and arrests the tumor cell cycle in G0/G1 phase. HSP90-IN-23 can be used for cancer research .

HY-B0779R

Teprenone (Standard) Geranylgeranylacetone (Standard)	Reference Standards HSP	Neurological Disease Cancer
Teprenone (Standard) is the analytical standard of Teprenone. This product is intended for research and analytical applications. Teprenone is an anti-ulcer agent, and works as an inducer of heat shock proteins (HSPs).

HY-132995

DP-1	Drug Metabolite	Others
DP-1, a degradation product of SDC-TRAP-0063, is a fragment of Ganetespib. Ganetespib is a heat shock protein 90 (HSP90) inhibitor with anti-tumor activity .

HY-122876

KUNB31	HSP	Cancer
KUNB31 is a selective inhibitor of SP90β with an K_d value of 0.18 μM .

HY-W107935

Hsp90-IN-37	HSP	Cancer
Hsp90-IN-37 (Z-2) is a heat shock protein 90 (Hsp90) inhibitor that inhibits Hsp90 enzymatic activity by 69%. Hsp90-IN-37 has antitumor activity .

HY-161765

iHSP110-33	HSP STAT	Cancer
iHSP110-33 is an inhibitor for heat shock protein 110 (HSP110). iHSP110-33 exhibits antitumor efficacy agaisnt large B-cell lymphoma and classical Hodgkin lymphoma. iHSP110-33 shows a synergistic effect with Selinexor (HY-17536), inhibits the STAT6 phosphorylation, and enhances its antitumor activity. .

HY-17504R

Rosuvastatin Calcium (Standard) 10+ Cited Publications Rosuvastatin hemicalcium (Standard); ZD 4522 Calcium (Standard)	Reference Standards HMG-CoA Reductase (HMGCR) Autophagy Potassium Channel Bacterial	Cardiovascular Disease Metabolic Disease Cancer
Rosuvastatin (Calcium) (Standard) is the analytical standard of Rosuvastatin (Calcium). This product is intended for research and analytical applications. Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC₅₀ of 195 nM . Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

HY-N0293R

Paeoniflorin (Standard) Peoniflorin (Standard)	Reference Standards HSP	Infection Neurological Disease Cancer
Paeoniflorin (Standard) is the analytical standard of Paeoniflorin. This product is intended for research and analytical applications. Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .

HY-N7085R

Citropten (Standard) 5,7-Dimethoxycoumarin (Standard); Limettin (Standard)	ERK JNK p38 MAPK Reference Standards	Neurological Disease Inflammation/Immunology Cancer
Citropten (Standard) is the analytical standard of Citropten. This product is intended for research and analytical applications. Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through **heat shock protein-70, monoamine oxidase-A** and inhibition of apoptosis .

HY-N14780

Pochonin D (+)-Pochonin D	HSP Interleukin Related Enterovirus	Infection Inflammation/Immunology Cancer
Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affects the homeostasis, folding and assembly processes of viral proteins, and reduces the replication capacity of viruses. Pochonin D reduces the infiltration of inflammatory cells, decreases the secretion of inflammatory cytokines such as TNF-α and IL-1β, and alleviates inflammatory responses. Pochonin D is a promising candidate for research on human rhinovirus (HRV) infection and cancer .

HY-17504AS1

Rosuvastatin-d6 ZD 4522-d₆	Isotope-Labeled Compounds Autophagy Bacterial HMG-CoA Reductase (HMGCR) Potassium Channel	Cardiovascular Disease Metabolic Disease Cancer
Rosuvastatin-d₆ (ZD 4522-d₆) is deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC₅₀ of 11 nM. Rosuvastatin potently blocks hERG current with an IC₅₀ of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

HY-113916

Onalespib lactate AT13387 lactate	HSP	Cancer
Onalespib lactate is a potent and cross the blood-brain barrier heat-shock-protein-90 (Hsp90) inhibitor with an K_d value of 0.71 nM. Onalespib lactate inhibits the proliferation, survival and migration. Onalespib lactate decreases the expression of EGFR, p-EGFR, AKT, P-AKT, ERK1/2, P-ERK1/2, S6, P-S6 protein. Onalespib lactate shows antitumor activity. Onalespib lactate has the potential for the research of non-small cell lung cancer (NSCLC) .

HY-176279

Hsp90-IN-42	HSP	Cancer
Hsp90-IN-42 (Compound 13l) is a potent heat shock protein 90 (Hsp90) inhibitor (IC₅₀=15.65 nM). Hsp90-IN-42 reduces the stability of the epidermal growth factor receptor (EGFR), suppressing the activation of the EGFR-Akt signaling pathway, inducing G0/G1 phase arrest in colorectal cancer cells (such as HT-29 cells), and slightly triggering apoptosis. Hsp90-IN-42 also inhibits cell proliferation and migration by down-regulating the expression of CDK12, CDK13, and Bcl-2 proteins, and up-regulating the expression of Bax protein. Hsp90-IN-42 is promising for research of colorectal cancer .

HY-17504BS1

Rosuvastatin-d6 sodium	HMG-CoA Reductase (HMGCR) Autophagy	Cardiovascular Disease Metabolic Disease
Rosuvastatin-d₆ sodium is deuterium labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC₅₀ of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

HY-125974A

HM03 trihydrochloride	HSP	Cancer
HM03 trihydrochloride is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity .

HY-143400

HSP70-IN-3	HSP Hedgehog	Cancer
HSP70-IN-3 is a potent HSP70 inhibitor (IC₅₀s of 1.1 and 1.9 μM in ASZ001 and C3H10T1/2, respectively). HSP70-IN-3 has anti-Hh (Hedgehog signaling) activity and anti-proliferative activity and reduces expression of the oncogenic transcription factor GLI1 .

Cat. No.	Product Name	Type

HY-D1063

IR-780

5+ Cited Publications

Fluorescent Dyes

IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .

Cat. No.	Product Name	Type

HY-142980

DOPG

Dioleoylphosphatidylglycerol

Biochemical Assay Reagents

DOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0293

Paeoniflorin Maximum Cited Publications 38 Publications Verification Peoniflorin	Other Monoterpenes Paeonia lactiflora Pall. Terpenoids Plants Paeoniaceae Source Classification	HSP
Paeoniflorin is a **heat shock protein**-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .

HY-B0425A

Novobiocin sodium 10+ Cited Publications Albamycin sodium; Cathomycin sodium	Microorganisms Anti-inflammation/Immunoregulatory Classification of Application Fields Antibiotics Antiviral Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification Cancer	Bacterial Antibiotic Orthopoxvirus Apoptosis DNA/RNA Synthesis HSP
Novobiocin (Albamycin) sodium is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity .

HY-W014102

L-Alanyl-L-glutamine 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations .

HY-N6769

Radicicol 4 Publications Verification Monorden	Antifungal Classification of Application Fields Marine natural products Anti-parasitic Disease Research Infection Microorganisms Macrolide Antibiotics Antibiotics Phenols Polyphenols Marine microorganism Disease Research Fields Source Classification	HSP Bacterial Antibiotic Parasite
Radicicol is an inhibitor of Hsp90 with an IC₅₀ value < 1 μM, and leads to proteasomal degradation . Radicicol exhibits inhibition on PDK with IC₅₀s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB . Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC₅₀ value of 16.04 μM .

HY-N1934

Dihydroberberine	Cardiovascular Disease Alkaloids other families Classification of Application Fields Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields Source Classification	Potassium Channel HSP
Dihydroberberine is a naturally occurring isoquinoline alkaloid with anti-inflammatory, anti-atherosclerotic, hypolipidemic and anti-tumor activities. Dihydroberberine inhibits the human ether-related gene (hERG) channel and significantly reduces the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine also blocks the TLR4/MyD88/NF-κB signaling pathway to reduce pro-inflammatory cytokines and immunoglobulins, and has inhibitory effects on DSS (HY-116282C)-induced experimental colitis. Dihydroberberine also increases the sensitivity of lung cancer to sunitinib (HY-10255A), with synergistic efficacy .

HY-N7085

Citropten 5,7-Dimethoxycoumarin; Limettin	Structural Classification Classification of Application Fields Rutaceae Coumarins Phenylpropanoids Plants Disease Research Fields Citrus medica Linn. var. sarcodactylis (Noot.) Swingle Cancer	Environmental Pollutants ERK p38 MAPK JNK
Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through **heat shock protein-70, monoamine oxidase-A** and inhibition of apoptosis .

HY-N2815

Ursolic acid acetate Acetylursolic acid; 3-Acetylursolic acid	Triterpenes other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification Cancer	Parasite HSP
Ursolic acid acetate (Acetylursolic acid) is a triterpenoid compound and an inhibitor of Plasmodium falciparum heat shock protein 90 (PfHsp90) with a K_D of 8.16 μM. Ursolic acid acetate is cytotoxic to KB cells, with an IC₅₀ value of 8.4 μM. Ursolic acid acetate can be used in tumor and antimalarial research .

HY-N0754

Eupalinolide A	Structural Classification Classification of Application Fields Melilotus albus Desr. Terpenoids Sesquiterpenes Plants Compositae Inflammation/Immunology Disease Research Fields Source Classification	YAP HSP Reactive Oxygen Species (ROS) ERK Autophagy Apoptosis Tyrosinase DNA/RNA Synthesis
Eupalinolide A is a Yes-associated protein (YAP) degrader and HSP70 inducer. Eupalinolide A inhibits osteogenic differentiation of tendon-derived stem cells (TDSCs). Eupalinolide A induces autophagy in hepatocellular carcinoma cells via activating the ROS/ERK signaling pathway. Eupalinolide A protects PAM212 cells from UVB-, Menadione (HY-B0332)-, or heat shock-induced apoptosis. Eupalinolide A alleviates trauma-induced heterotopic ossification (HO) of Achilles tendon and inhibits growth of MHCC97-L and HCCLM3 hepatocellular carcinoma xenograft tumors in mice. Eupalinolide A can be used for the study of traumatic heterotopic ossification of tendons and hepatocellular carcinoma .

HY-N7627

Regaloside C	Cardiovascular Disease Structural Classification Classification of Application Fields Simple Phenylpropanols Gramineae Secale cereale Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Source Classification	Estrogen Receptor/ERR Toll-like Receptor (TLR) Akt MMP HSP
Regaloside C is an anti-inflammatory agent and antioxidant that scavenges ABTS and DPPH free radicals. Regaloside C targets multiple molecules including TNF-α, MMP-2, ERα, AKT1, TLR4 and HSP90-α. Regaloside C is applicable to research related to inflammatory diseases .

HY-N0293R

Paeoniflorin (Standard) Peoniflorin (Standard)	Structural Classification Other Monoterpenes Paeonia lactiflora Pall. Terpenoids Plants Paeoniaceae Source Classification	Reference Standards HSP
Paeoniflorin (Standard) is the analytical standard of Paeoniflorin. This product is intended for research and analytical applications. Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .

HY-N7085R

Citropten (Standard) 5,7-Dimethoxycoumarin (Standard); Limettin (Standard)	Structural Classification Rutaceae Coumarins Phenylpropanoids Plants Citrus medica Linn. var. sarcodactylis (Noot.) Swingle	ERK JNK p38 MAPK Reference Standards
Citropten (Standard) is the analytical standard of Citropten. This product is intended for research and analytical applications. Citropten (5, 7-dimethoxycoumarin) is one of the coumarin derivatives. Citropten is an effective oral anticancer agent. Citropten has anti-proliferative activity against A2058 and B16 melanoma cells. Citropten exerts anti-inflammatory effects through the NFκB and MAPK signaling pathways. Citropten acts as an antidepressant through **heat shock protein-70, monoamine oxidase-A** and inhibition of apoptosis .

HY-N14780

Pochonin D (+)-Pochonin D	Structural Classification Natural Products Microorganisms Source Classification	HSP Interleukin Related Enterovirus
Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affects the homeostasis, folding and assembly processes of viral proteins, and reduces the replication capacity of viruses. Pochonin D reduces the infiltration of inflammatory cells, decreases the secretion of inflammatory cytokines such as TNF-α and IL-1β, and alleviates inflammatory responses. Pochonin D is a promising candidate for research on human rhinovirus (HRV) infection and cancer .

HY-N1934R

Dihydroberberine (Standard)	Alkaloids Structural Classification other families Plants Isoquinoline Alkaloids Source Classification	Reference Standards Potassium Channel HSP
Dihydroberberine (Standard) is the analytical standard of Dihydroberberine. This product is intended for research and analytical applications. Dihydroberberine is a naturally occurring isoquinoline alkaloid with anti-inflammatory, anti-atherosclerotic, hypolipidemic and anti-tumor activities. Dihydroberberine inhibits the human ether-related gene (hERG) channel and significantly reduces the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine also blocks the TLR4/MyD88/NF-κB signaling pathway to reduce pro-inflammatory cytokines and immunoglobulins, and has inhibitory effects on DSS (HY-116282C)-induced experimental colitis. Dihydroberberine also increases the sensitivity of lung cancer to sunitinib (HY-10255A), with synergistic efficacy .

HY-W014102R

L-Alanyl-L-glutamine (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
L-Alanyl-L-glutamine (Standard) is the analytical standard of L-Alanyl-L-glutamine. This product is intended for research and analytical applications. L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations .

HY-N13240

Ginseng Extract	Classification of Application Fields Anti-aging Plants Disease Research Fields Araliaceae Source Classification	Others
Ginseng Extract is a ginseng extract, and its components include: Ginsenosides. Ginseng Extract is an excellent animal nutrition feed additive that can reduce the negative effects of heat stress on animal physiology. Studies have shown that Ginseng Extract can prolong the survival time of Caenorhabditis elegans under heat stress, and its mechanism is related to the upregulation of gene expression of specific heat shock proteins and tight junction proteins. .

HY-N10352

4-epi-Withaferin A	Classification of Application Fields Withania somnifera Plants Solanaceae Disease Research Fields Steroids Cancer Source Classification	Others
4-epi-Withaferin A (compound 28) is the analogue of Withaferin A. 4-epi-Withaferin A enhances cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). 4-epi-Withaferin A has the potential for the research of protein aggregation-associated diseases by stimulating cellular defense mechanisms .

HY-N12887

Mycothiazole	Natural Products Marine natural products Sponge Source Classification	Mitochondrial Metabolism
Mycothiazole is an inhibitor for mitochondrial electron transport chain (ETC) complex I. Mycothiazole exhibits cytotoxicity in cancer cells Huh7 (IC₅₀ is 55.8 μM), U87 and MCF7. Mycothiazole induces apoptosis in Huh7. Mycothiazole utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathway involved transcription factors ATFS-1 and HSF1, to extend the lifespan of C. elegans .

Species:	Human (28) Rat (1) Mouse (2) E.coli (2)
Tag:	SUMO (1) His (30) Tag Free (2) Strep (1) Avi (1) GST (2)
Source:	HEK293 (3) Sf9 insect cells (2) P. pastoris (3) E. coli (26)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70929

	HSPB7 Protein, Human (His) Heat shock protein beta-7; Cardiovascular Heat shock protein (cvHsp); CVHSP	Human	E. coli
	PSG2 protein engages in interactions with the C-terminal domain of actin-binding protein 280. HSPB7 Protein, Human (His) is the recombinant human-derived HSPB7 protein, expressed by E. coli, with C-6*His labeled tag.

HY-P703148

	HSPA1L Protein, Human (His, Strep) Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 1-Hom; HSP70-Hom; Heat shock protein family A member 1L; HSPA1L; Homo sapiens; Human; Heat shock 70 kDa protein 1L	Human	E. coli
	HSPA1L Protein, Human (His, Strep) is the recombinant human-derived HSPA1L, expressed by E. coli , with Strep, His labeled tag.

HY-P701385

	HSPA2 Protein, Human (His) HSPA2; Heat shock-related 70 kDa protein 2; Heat shock 70 kDa protein 2	Human	E. coli
	The HSPA2 protein is a molecular chaperone that protects the proteome, aids in protein folding and transport, activates proteolysis, and regulates protein complex formation. It ensures accurate protein folding and degradation, with substrate affinity related to its nucleotide status. HSPA2 Protein, Human (His) is the recombinant human-derived HSPA2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71824

	HSP70/DnaK Protein, E. coli (P.pastoris, His) dnaK; HSP70; Heat shock 70kDa protein; Heat shock protein 70	E.coli	P. pastoris
	The HSP70/DnaK protein is a molecular chaperone that primarily responds to stress, especially heat shock. It plays a crucial role in helping proteins fold correctly and prevent misfolding or aggregation during cellular stress. HSP70/DnaK Protein, E. coli (P.pastoris, His) is the recombinant E. coli-derived HSP70/DnaK protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P71487

	HtpG Protein, E.coli htpG; b0473; JW0462; Chaperone protein HtpG; Heat shock protein C62.5; Heat shock protein HtpG; High temperature protein G	E.coli	E. coli
	HtpG protein, a molecular chaperone, functions with ATPase activity and homodimerizes, demonstrating unique oligomerization at 65 degrees Celsius. HtpG Protein, E.coli is the recombinant E. coli-derived HtpG protein, expressed by E. coli , with tag free.

HY-P703083

	HSP90AA1 Protein, Human (His, Avi) Heat shock protein HSP 90-alpha; Heat shock 86 kDa (HSP 86; HSP86); Heat shock protein family C member 1; Lipopolysaccharide-associated protein 2 (LAP-2; LPS-associated protein 2); Renal carcinoma antigen NY-REN-38; HSP90A, HSPC1, HSPCA	Human	E. coli
	The HSP90AA1 protein is an important molecular chaperone that coordinates the maturation and regulation of specific target proteins critical for cell cycle control and signal transduction. Its ATPase activity drives a functional cycle that induces conformational changes in client proteins for activation. HSP90AA1 Protein, Human (His, Avi) is the recombinant human-derived HSP90AA1, expressed by E. coli, with C-Avi, C-6*His labeled tag.

HY-P70406

	HSF2 Protein, Human (His) rHuHeat shock factor protein 2/HSF2, His; Heat shock Factor protein 2; HSF 2; Heat shock Transcription Factor 2; HSTF 2; HSF2; HSTF2	Human	E. coli
	As a DNA-binding protein, HSF2 protein has specific affinity for the heat shock promoter element (HSE), thereby activating transcription. Notably, in higher eukaryotes, the ability of HSF2 to bind to HSE depends on the exposure of cells to heat shock. HSF2 Protein, Human (His) is the recombinant human-derived HSF2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P72238

	HSP90AA1 Protein, Human (His-SUMO) 2 Publications Verification Heat shock 86 kDa; Heat shock protein 90kDa alpha cytosolic class A member 1; Heat shock protein 90kDa alpha cytosolic class B member 1; Heat shock protein HSP 90 alpha ; Heat shock protein HSP 90 beta; Heat shock protein HSP 90-alpha; HS90A_HUMAN; HSP 84; HSP 86; Hsp 90; HSP86; HSP90A; HSP90AA1; HSP90AB1; HSP90B; HSPC1; HSPC2; HSPCAL1 ; HSPCAL4; Renal carcinoma antigen NY-REN-38	Human	E. coli
	The HSP90AA1 protein is an important molecular chaperone that coordinates the maturation and regulation of specific target proteins critical for cell cycle control and signal transduction. Its ATPase activity drives a functional cycle that induces conformational changes in client proteins for activation. HSP90AA1 Protein, Human (His-SUMO) is the recombinant human-derived HSP90AA1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P70844

	HSPB2 Protein, Human (His) Heat shock protein beta-2; HspB2; DMPK-binding protein; MKBP	Human	E. coli
	HSPB2 Protein potentially regulates the kinase DMPK, enhancing its activity and influencing cellular processes. The specific mechanisms and broader implications in cellular signaling pathways require elucidation. Comprehensive studies are essential to unravel the precise molecular pathways and functional significance of the HSPB2-DMPK interplay, shedding light on its potential contributions to cellular regulation and signaling cascades. HSPB2 Protein, Human (His) is the recombinant human-derived HSPB2 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P790088

	HSPA5/GRP-78 Protein, Human (sf9, His) Binding-immunoglobulin protein; Heat shock protein 70 family protein 5; Heat shock protein family A member 5; Immunoglobulin heavy chain-binding protein; HSPA5; GRP78	Human	Sf9 insect cells
	HSPA5/GRP-78 is an endoplasmic reticulum chaperone that coordinates protein folding and quality control. It cooperates with DNAJC10/ERdj5 to facilitate correct protein folding and participates in the degradation of misfolded proteins, potentially releasing DNAJC10/ERdj5. HSPA5/GRP-78 Protein, Human (sf9, His) is the recombinant human-derived HSPA5, expressed by Sf9 insect cells, with C-10*His labeled tag.

HY-P73918

	HSF1 Protein, Human (His) Heat shock factor protein 1; HSF1; HSTF 1	Human	E. coli
	HSF1 is a stress-inducible transcription factor that coordinates the heat shock response by binding to the heat shock element (HSE) and activating heat shock genes. In unstressed cells, it remains inactive in multichaperone complexes. HSF1 Protein, Human (His) is the recombinant human-derived HSF1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P73916A

	HSP60 Protein, Mouse (His) 60 kDa Heat shock protein, mitochondrial; CPN60; HSP-60; HSPD1	Mouse	E. coli
	The HSP60 protein, together with Hsp10, contributes to the import and assembly of mitochondrial proteins. It ensures correct folding and prevents incorrect folding under stressful conditions. HSP60 Protein, Mouse (His) is the recombinant mouse-derived HSP60, expressed by E. coli, with N-10*His labeled tag.

HY-P73916

	HSP60 Protein, Mouse (His, solution) 1 Publications Verification 60 kDa Heat shock protein, mitochondrial; CPN60; HSP-60; HSPD1	Mouse	E. coli
	The HSP60 protein, together with Hsp10, contributes to the import and assembly of mitochondrial proteins. It ensures correct folding and prevents incorrect folding under stressful conditions. HSP60 Protein, Mouse (His, solution) is the recombinant mouse-derived HSP60 protein, expressed by E. coli , with N-His labeled tag.

HY-P73917

	HSP60 Protein, Human (His-GST) 1 Publications Verification 60 kDa Heat shock protein, mitochondrial; CPN60; HSP-60; HSPD1	Human	E. coli
	The HSP60 protein is a mitochondrial chaperone that facilitates protein import and assembly. HSP60 Protein, Human (His-GST) is the recombinant human-derived HSP60 protein, expressed by E. coli , with N-His, N-GST labeled tag.

HY-P74877

	HSP70/HSPA1A Protein, Human (HEK293, His) 1 Publications Verification Heat shock 70 kDa protein 1A; HSP70-1; HSPA1A; HSP72	Human	HEK293
	The HSP70/HSPA1A protein is an important molecular chaperone that protects proteome integrity by counteracting stress, aiding protein folding, activating misfolded proteolysis, and regulating protein complex dynamics. In protein quality control systems, it ensures accurate protein folding, controls substrate targeting for degradation through the ATP cycle, and interacts with co-chaperones such as HSP40, BAG1/2/3, HOPX, and STUB1. HSP70/HSPA1A Protein, Human (HEK293, His) is the recombinant human-derived HSP70/HSPA1A protein, expressed by HEK293 , with N-His labeled tag.

HY-P73105

	HSP70/HSPA1B Protein, Human (SF9, His) Heat shock 70 kDa protein 1B; HSP70-2; HSPA1B; HSP72	Human	Sf9 insect cells
	The HSP70/HSPA1B protein is an important molecular chaperone that ensures proteome integrity by protecting against stress, aiding in protein folding, activating proteolysis, and regulating protein complex assembly. It remains accurately folded through the ATP cycle and co-chaperones such as HSP40, BAG1/2/3, HOPX and STUB1. HSP70/HSPA1B Protein, Human (SF9, His) is the recombinant human-derived HSP70/HSPA1B protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P70116

	Cornulin Protein, Human (His) rHuCornulin, His; Cornulin; 53 kDa Putative Calcium-Binding protein; 53 kDa Squamous Epithelial-Induced Stress protein; 58 kDa Heat shock protein; Squamous Epithelial Heat shock protein 53; Tumor-Related protein; CRNN; C1orf10; DRC1; PDRC1; SEP53	Human	E. coli
	Cornulin protein is critical in cell dynamics, promoting proliferation and promoting G1/S cell cycle progression, inducing the key regulator CCND1. It actively participates in the NFKB1 and PI3K/AKT pathways and responds to pro-inflammatory cytokines. Cornulin Protein, Human (His) is the recombinant human-derived Cornulin protein, expressed by E. coli , with N-6*His labeled tag.

HY-P704486

	HSPA5/GRP-78 Protein, Human (P.pastoris, His) Endoplasmic reticulum chaperone BiP; HSPA5; 78 kDa glucose-regulated protein; Binding-immunoglobulin protein; Heat shock protein 70 family protein 5; Heat shock protein family A member 5; Immunoglobulin heavy chain-binding protein; GRP78	Human	P. pastoris
	HSPA5/GRP-78 is an endoplasmic reticulum chaperone that coordinates protein folding and quality control. It cooperates with DNAJC10/ERdj5 to facilitate correct protein folding and participates in the degradation of misfolded proteins, potentially releasing DNAJC10/ERdj5. HSPA5/GRP-78 Protein, Human (P.pastoris, His) is the recombinant human-derived HSPA5/GRP-78 protein, expressed by P. pastoris, with C-6*His labeled tag.

HY-P73915A

	HSPA8/HSC70 Protein, Human (His) Heat shock cognate 71 kDa protein; LAP-1; HSPA8; HSC70	Human	E. coli
	HSPA8/HSC70 is a molecular chaperone that protects the proteome and aids in peptide folding, transport, chaperone-mediated autophagy, and protein complex regulation. It is central to quality control, ensuring correct folding and targeting misfolded proteins for degradation through ATP-dependent cycles. HSPA8/HSC70 Protein, Human (His) is the recombinant human-derived HSPA8/HSC70 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70331

	HSP40/DNAJB1 Protein, Human (His) 1 Publications Verification rHuDnaJ homolog subfamily B member 1/HSP40, His; DnaJ Homolog Subfamily B Member 1; DnaJ protein Homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1; DNAJB1; DNAJ1; HDJ1; HSPF1	Human	E. coli
	HSP40/DNAJB1 protein, a key player in cellular processes, interacts with HSP70 to enhance ATPase activity and stimulate HSC70-HIP association. It negatively regulates HSF1 transcriptional activity in heat shock response recovery, and interacts with DNAJC3 and HSF1, inhibiting their transcriptional activity. These multifaceted interactions showcase HSP40/DNAJB1's intricate regulatory functions in stress responses and protein folding. HSP40/DNAJB1 Protein, Human (His) is the recombinant human-derived HSP40/DNAJB1 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P73915

	HSPA8/HSC70 Protein, Human (His, Solution) 1 Publications Verification Heat shock cognate 71 kDa protein; LAP-1; HSPA8; HSC70	Human	E. coli
	HSPA8/HSC70 is a molecular chaperone that protects the proteome and aids in peptide folding, transport, chaperone-mediated autophagy, and protein complex regulation. It is central to quality control, ensuring correct folding and targeting misfolded proteins for degradation through ATP-dependent cycles. HSPA8/HSC70 Protein, Human (His, Solution) is the recombinant human-derived HSPA8/HSC70 protein, expressed by E. coli , with N-His labeled tag.

HY-P705984

	HSPA5/GRP-78 Protein, Cricetulus griseus (HEK293, His) Endoplasmic reticulum chaperone BiP; EC:3.6.4.10; 8 kDa glucose-regulated protein; Binding-immunoglobulin protein; Heat shock protein 70 family protein 5; Heat shock protein family A member 5; Immunoglobulin heavy chain-binding protein ; HSPA5; GRP78; I79_019946	Others	HEK293

HY-P71537

	TRAP1 Protein, Human (GST) Heat shock protein 75kDa; Heat shock protein 75kDa, mitochondrial; HSP 75; HSP75; HSP90L; mitochondrial; TNF receptor associated protein 1; TNFR-associated protein 1; TRAP-1; Trap1; TRAP1_HUMAN; Tumor necrosis factor type 1 receptor-associated protein	Human	E. coli
	As a chaperone with ATPase activity, TRAP1 protein plays a crucial role in protecting mitochondrial function and polarization, especially downstream of PINK1 and mitochondrial complex I. TRAP1 acts as a negative regulator of mitochondrial respiration, affecting the balance between oxidative phosphorylation and aerobic glycolysis. TRAP1 Protein, Human (GST) is the recombinant human-derived TRAP1 protein, expressed by E. coli , with N-GST labeled tag.

HY-P70945

	HSPB11 Protein, Human (His) Heat shock protein Beta-11; Hspb11; Placental protein 25; PP25; HSPB11; C1orf41	Human	E. coli
	The HSPB11 protein is an important component of IFT complex B and is indispensable for sonic eager/SHH signaling. It promotes intraflagellar transport in ciliated tissues such as kidney and testis, mediating the transport of SHH components. HSPB11 Protein, Human (His) is the recombinant human-derived HSPB11 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P76283

	HSP10/EPF Protein, Human (His) 1 Publications Verification 10 kDa Heat shock protein, mitochondrial; Hsp10; Chaperonin 10; CPN10; EPF; HSPE1	Human	E. coli
	The HSP10/EPF protein is a cochaperone that plays a role in mitochondrial protein import and assembly. HSP10/EPF Protein, Human (His) is the recombinant human-derived HSP10/EPF protein, expressed by E. coli , with N-His, N-6*His labeled tag.

HY-P705926

	HSPA8/HSC70 Protein, Human (P. pastoris, His) Heat shock cognate 71 kDa protein; LAP-1; HSPA8; HSC70	Human	P. pastoris
	HSPA8/HSC70 is a molecular chaperone that protects the proteome and aids in peptide folding, transport, chaperone-mediated autophagy, and protein complex regulation. It is central to quality control, ensuring correct folding and targeting misfolded proteins for degradation through ATP-dependent cycles. HSPA8/HSC70 Protein, Human (P. pastoris, His) is the recombinant human-derived HSPA8/HSC70 protein, expressed by P. pastoris , with N-His labeled tag.

HY-P74878

	HSP27/HSPB1 Protein, Human (His) Heat shock protein beta-1; HspB1; HSP 27; SRP27; HSPB1; HSP28	Human	E. coli
	The HSP27/HSPB1 protein is a small heat shock protein that acts as a molecular chaperone, possibly maintaining denatured proteins in a foldable state. In addition to its chaperone role, it crucially enhances stress resistance and contributes to actin organization. HSP27/HSPB1 Protein, Human (His) is the recombinant human-derived HSP27/HSPB1 protein, expressed by E. coli , with C-His labeled tag.

HY-P701386

	HSPBP1 Protein, Human HSPBP1; Hsp70-binding protein 1; HspBP1; Heat shock protein-binding protein 1; Hsp70-binding protein 2; HspBP2; Hsp70-interacting protein 1; Hsp70-interacting protein 2	Human	E. coli
	HSPBP1 protein regulates HSPA1A chaperone activity by inducing conformational changes in the ATP-binding domain and disrupting ATP binding. This interference inhibits the STUB1-mediated ubiquitination process and blocks chaperone-assisted degradation of immature CFTR. HSPBP1 Protein, Human is the recombinant human-derived HSPBP1 protein, expressed by E. coli , with tag free.

HY-P701387

	HSPBP1 Protein, Human (E88G, His) HSPBP1; Hsp70-binding protein 1; HspBP1; Heat shock protein-binding protein 1; Hsp70-binding protein 2; HspBP2; Hsp70-interacting protein 1; Hsp70-interacting protein 2	Human	E. coli
	HSPBP1 protein regulates HSPA1A chaperone activity by inducing conformational changes in the ATP-binding domain and disrupting ATP binding. This interference inhibits the STUB1-mediated ubiquitination process and blocks chaperone-assisted degradation of immature CFTR. HSPBP1 Protein, Human (E88G, His) is the recombinant human-derived HSPBP1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70933

	HSPB8 Protein, Human (His) 1 Publications Verification Heat shock protein beta-8; HspB8; Alpha-crystallin C chain; E2-induced gene 1 protein; protein kinase H11; Small stress protein-like protein HSP22; HSPB8; CRYAC; E2IG1; HSP22	Human	E. coli
	The HSPB8 protein exhibits temperature-dependent chaperone activity and functions as a monomer in its molecular form.It interacts with other cellular proteins to form complexes critical for cellular homeostasis.HSPB8 Protein, Human (His) is the recombinant human-derived HSPB8 protein, expressed by E.coli , with C-6*His labeled tag.

HY-P7872

	Alpha-crystallin A chain/CRYAA Protein, Human (His) rHuAlpha-crystallin A chain/CRYAA, His; Alpha-Crystallin A Chain; Heat shock protein Beta-4; HspB4; Alpha-Crystallin A Chain; Short Form; CRYAA; CRYA1; HSPB4	Human	E. coli
	Alpha-crystallin A chain/CRYAA Protein, Human (His) is a recombinant Alpha-crystallin A chain protein with a His tag. Alpha-crystallin A chain/CRYAA is a small heat shock protein and molecular chaperone that prevents nonspecific aggregation of denaturing proteins. Several point mutations in the alphaA-crystallin gene cause congenital human cataracts by unknown mechanisms.

HY-P705717

	Alpha-crystallin A chain/CRYAA Protein, Rat (His) rHuAlpha-crystallin A chain/CRYAA, His; Alpha-Crystallin A Chain; Heat shock protein Beta-4; HspB4; Alpha-Crystallin A Chain; Short Form; CRYAA; CRYA1; HSPB4	Rat	E. coli
	Alpha-crystallin A chain/CRYAA Protein, Rat (His) is a recombinant Alpha-crystallin A chain protein with a His tag. Alpha-crystallin A chain/CRYAA is a small heat shock protein and molecular chaperone that prevents nonspecific aggregation of denaturing proteins.

HY-P71298

	Serpin H1 Protein, Human (HEK293, His) Serpin H1; 47 kDa Heat shock protein; Arsenic-Transactivated protein 3; AsTP3; Cell Proliferation-Inducing Gene 14 protein; Collagen-Binding protein; Colligin; Rheumatoid Arthritis-Related Antigen RA-A47; SERPINH1; CBP1; CBP2; HSP47; SERPINH2	Human	HEK293
	Serpin H1 protein exhibits a specific affinity for collagen, indicating its role as a chaperone in the biosynthetic pathway of collagen. This suggests its potential contribution to collagen synthesis, emphasizing its importance in maintaining tissue integrity and modulating cellular responses related to collagen metabolism. Serpin H1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin H1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7873

	Alpha-crystallin B chain/CRYAB Protein, Human (His) 1 Publications Verification rHuAlpha-crystallin B chain/CRYAB, His; Alpha-Crystallin B Chain; Alpha(B)-Crystallin; Heat shock protein Beta-5; HspB5; Renal Carcinoma Antigen NY-REN-27; Rosenthal Fiber Component; CRYAB; CRYA2	Human	E. coli
	Alpha-crystallin B chain/CRYAB Protein, Human (His) expresses in E. coli with a His tag at the N-terminus. CRYAB is an important member of the small heat shock protein family, and plays a protective role in neurological inflammation.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-17504AS1

Rosuvastatin-d6

Rosuvastatin-d₆ (ZD 4522-d₆) is deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC₅₀ of 11 nM. Rosuvastatin potently blocks hERG current with an IC₅₀ of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

HY-17504BS1

Rosuvastatin-d6 sodium

Rosuvastatin-d₆ sodium is deuterium labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC₅₀ of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

HY-17504BS2

Rosuvastatin-13C,d3 sodium

Rosuvastatin- ¹³C,d₃ sodium is ¹³C and deuterated labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC₅₀ of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC₅₀ of 195 nM . Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .

Host:	Mouse (21) Rabbit (34)
Reactivity:	Human (55) Rat (35) Mouse (39) Monkey (3) Hamster (3)
Application:	IHC-P (35) ICC/IF (33) IF-Tissue (3) IP (26) IHC-F (6) WB (54) FC (9) ELISA (8)
Isotype:	IgG (38) IgG1 (3) IgG2a (2) IgG2b (4)
Conjugation:	Non-conjugated (55)
Clonality:	Polyclonal (2) polyclonal (1) Monoclonal (39) Recombinant (18)
Modification:	Phosphorylated (5) Unmodified (37)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P80708

	HSC70 Antibody (YA360) 1 Publications Verification Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)	WB, IHC-P, IP	Human, Mouse, Rat, Hamster
	HSC70 Antibody (YA360) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HSC70.

HY-P85704

	HSC70 Antibody (YA5396) Heat shock cognate 71 kDa protein; Heat shock 70 kDa protein 8;	IHC-P, WB	Human, Mouse, Rat
	HSC70 Antibody (YA5396) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HSC70.

HY-P86906

	HSPA1L Antibody (YA6599) Heat shock 70 kDa protein 1 Hom antibody; Heat shock 70 kDa protein 1 like antibody; Heat shock 70 kDa protein 1-Hom antibody; Heat shock 70 kDa protein 1-like antibody; Heat shock 70 kDa protein 1L antibody; Heat shock 70kD protein like 1 antibody; HS71L_HUMAN antibody; HSP70 1L antibody; HSP70 HOM antibody; HSP70-Hom antibody; Heat shock 70 kDa protein 1 Hom antibody; Heat shock 70 kDa protein 1 like antibody; Heat shock 70 kDa protein 1-Hom antibody; Heat shock 70 kDa protein 1-like antibody; Heat shock 70 kDa protein 1L antibody; Heat shock 70kD protein like 1 antibody; HS71L_HUMAN antibody; HSP70 1L antibody; HSP70 HOM antibody; HSP70-Hom antibody; HSPA1L antibody; hum70t antibody; Spermatid specific Heat shock protein 70 antibody;	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	HSPA1L Antibody (YA6599) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HSPA1L.

HY-P80708A

	HSC70 Antibody (YA360)(PBS only) Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)	WB, IHC-P, IP	Human, Mouse, Rat, Hamster
	HSC70 Antibody (YA360) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HSC70.

HY-P83311

	HspA2 Antibody (YA3056) 1 Publications Verification HSPA2; Heat shock 70kD protein 2; HSP70-2; HSP70-3; Heat shock 70 kDa protein 2; Heat shock 70kDa protein 2	WB, IHC-P	Human, Mouse, Rat
	HspA2 Antibody (YA3056) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA2.

HY-P83311A

	HspA2 Antibody (YA3056)(PBS only) HSPA2; Heat shock 70kD protein 2; HSP70-2; HSP70-3; Heat shock 70 kDa protein 2; Heat shock 70kDa protein 2	WB, IHC-P	Human, Mouse, Rat
	HspA2 Antibody (YA3056) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA2.

HY-P86734

	HSC70 Antibody (YA6426) 2410008N15Rik; Constitutive Heat shock protein 70; Heat shock 70 kDa protein 8; Heat shock 70kD protein 10; Heat shock 70kD protein 8; Heat shock 70kDa protein 8; Heat shock cognate 71 kDa protein; Heat shock cognate protein 54; Heat shock cognate protein 71 kDa; Heat shock protein 8; Heat shock protein A8; Heat-shock70-KD protein 10, formerly; HSC54; HSC71; Hsc73; HSP71; HSP73; HSP7C_HUMAN; HSPA10; HSPA8; LAP1; Lipopolysaccharide associated protein 1; LPS associated protein 1; LPS associated protein; MGC102007; MGC106514; MGC114311; MGC118485; MGC131511; MGC29929; N-myristoyltransferase inhibitor protein 71; NIP71; HSC 70; HSC-70.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
	HSC70 Antibody (YA6426) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to HSC70.

HY-P86734A

	HSC70 Antibody (YA6426)(PBS only) 2410008N15Rik; Constitutive Heat shock protein 70; Heat shock 70 kDa protein 8; Heat shock 70kD protein 10; Heat shock 70kD protein 8; Heat shock 70kDa protein 8; Heat shock cognate 71 kDa protein; Heat shock cognate protein 54; Heat shock cognate protein 71 kDa; Heat shock protein 8; Heat shock protein A8; Heat-shock70-KD protein 10, formerly; HSC54; HSC71; Hsc73; HSP71; HSP73; HSP7C_HUMAN; HSPA10; HSPA8; LAP1; Lipopolysaccharide associated protein 1; LPS associated protein 1; LPS associated protein; MGC102007; MGC106514; MGC114311; MGC118485; MGC131511; MGC29929; N-myristoyltransferase inhibitor protein 71; NIP71; HSC 70; HSC-70.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
	HSC70 Antibody (YA6426) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to HSC70.

HY-P83427

	HspA4 Antibody (YA3172) HSPA4; APG2; Heat shock 70 kDa protein 4; HSP70RY; Heat shock 70-related protein APG-2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	HspA4 Antibody (YA3172) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA4.

HY-P85596

	Hsp90 beta Antibody (YA5288) HSP90AB1; 90 kda Heat shock protein beta HSP90 beta; D6S182; FLJ26984; Heat shock 84 kDa; Heat shock 90kD protein 1, beta; Heat shock 90kDa protein 1 beta; Heat shock protein 90kDa alpha; cytosolic; class B member 1; Heat shock protein beta; Heat shock protein HSP 90 beta; Heat shock protein HSP 90-beta; HS90B_HUMAN; HSP 84; HSP 90; HSP 90 b; HSP 90b; HSP84; HSP90 BETA; hsp90ab1; HSP90B; HSPC2; HSPCB.	WB, ICC/IF, IP	Human, Mouse, Rat, Monkey, Hamster
	Hsp90 beta Antibody (YA5288) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Hsp90 beta.

HY-P88141

	HSPA6 Antibody (YA7825) Heat shock 70kDa protein 6 (HSP70B'); Heat shock 70kD protein 6 (HSP70B')	WB, ICC/IF, FC	Human
	HSPA6 Antibody (YA7825) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HSPA6.

HY-P83429

	Hsp20 Antibody (YA3174) HSPB6; HEL55; Hsp20; Heat-shock 20 kDa like-protein p20	WB, IHC-P, FC	Human, Mouse, Rat
	Hsp20 Antibody (YA3174) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp20.

HY-P83258

	HspA14 Antibody (YA3003) HSPA14; HSP60; HSP70L1; Heat shock 70 kDa protein 14; HSP70-like protein 1; Heat shock protein HSP60	WB, ICC/IF, IP	Human, Mouse
	HspA14 Antibody (YA3003) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA14.

HY-P80709

	Hsp27 Antibody (YA732) HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa Heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27	WB, ICC/IF	Human, Monkey
	Hsp27 Antibody (YA732) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Hsp27.

HY-P86095

	Hsp27 Antibody (YA5787) HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa Heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Hsp27 Antibody (YA5787) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp27.

HY-P83202

	HspA12A Antibody (YA2947) FLJ13874 antibody; Heat shock 70 kDa protein 12A antibody; Heat shock 70kD protein 12A antibody; Heat shock 70kDa protein 12A antibody; HS12A_HUMAN antibody; Hspa12a antibody; KIAA0417 antibody	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	HspA12A Antibody (YA2947) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA12A.

HY-P80823

	Phospho-Hsp27 (Ser78) Antibody HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa Heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27	WB, IHC-P, ICC/IF	Human
	Phospho-Hsp27 (Ser78) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-Hsp27 (Ser78).

HY-P80824

	Phospho-Hsp27 (Ser82) Antibody HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa Heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27	WB, IHC-P	Human
	Phospho-Hsp27 (Ser82) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-Hsp27 (Ser82).

HY-P80709A

	Hsp27 Antibody (YA732)(PBS only) HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa Heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27	WB, ICC/IF	Human, Monkey
	Hsp27 Antibody (YA732) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Hsp27.

HY-P88141A

	HSPA6 Antibody (YA7825)(PBS only) Heat shock 70kDa protein 6 (HSP70B'); Heat shock 70kD protein 6 (HSP70B')	ICC/IF, FC	Human
	HSPA6 Antibody (YA7825) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HSPA6.

HY-P83258A

	HspA14 Antibody (YA3003)(PBS only) HSPA14; HSP60; HSP70L1; Heat shock 70 kDa protein 14; HSP70-like protein 1; Heat shock protein HSP60	WB, ICC/IF, IP	Human, Mouse
	HspA14 Antibody (YA3003) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA14.

HY-P85508

	Hsp70(C-term) Antibody (YA5200) DAQB 147D11.1 001; FLJ54303; FLJ54370; FLJ54392; FLJ54408; FLJ75127; Heat shock 70 kDa protein 1; Heat shock 70 kDa protein 1/2; Heat shock 70 kDa protein 1A/1B; Heat shock 70kDa protein 1A; Heat shock 70kDa protein 1B; Heat shock induced protein; Heat shock protein 70; HSP70 1; HSP70 2; HSP70-1/HSP70-2; HSP70-1A; HSP70.1; HSP70.1/HSP70.2; HSP70I; HSP71_HUMAN; HSP72; HSPA1; HSPA1A; HSPA1B; XXbac BCX40G17.3 001.	WB, IP	Human
	Hsp70(C-term) Antibody (YA5200) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Hsp70(C-term).

HY-P85703

	Hsp40 Antibody (YA5395) DnaJ homolog subfamily B member 1; DnaJ protein homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1;	IHC-P, WB	Human, Mouse, Rat
	Hsp40 Antibody (YA5395) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Hsp40.

HY-P80714

	Hsp90 alpha/beta Antibody (YA356) HSP90AA1; HSP90A; HSPC1; HSPCA; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; HSP86; Renal carcinoma antigen NY-REN-38; HSP90AB1; HSP90B; HSPC2; HSPCB; Heat shock protein HSP 90-beta; HSP 90; Heat shock 84 kDa; HSP 84; HSP84	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Hsp90 alpha/beta Antibody (YA356) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp90 alpha/beta.

HY-P81052

	HSF1 Antibody (YA896) HSF1; HSTF1; Heat shock factor protein 1; HSF 1; Heat shock transcription factor 1; HSTF 1	WB, IHC-P, ICC/IF, IP, FC	Human
	HSF1 Antibody (YA896) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HSF1.

HY-P82490

	Hsf2 Antibody (YA2235) HSF2; HSTF2; Heat shock factor protein 2; HSF 2; Heat shock transcription factor 2; HSTF 2	WB, ICC/IF, FC	Human
	Hsf2 Antibody (YA2235) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsf2.

HY-P85654

	Hsp70 Antibody (YA5346) HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Hsp70 Antibody (YA5346) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Hsp70.

HY-P86589

	Hsp70 Antibody (YA6281) HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Hsp70 Antibody (YA6281) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp70.

HY-P80714A

	Hsp90 alpha/beta Antibody (YA356)(PBS only) HSP90AA1; HSP90A; HSPC1; HSPCA; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; HSP86; Renal carcinoma antigen NY-REN-38; HSP90AB1; HSP90B; HSPC2; HSPCB; Heat shock protein HSP 90-beta; HSP 90; Heat shock 84 kDa; HSP 84; HSP84	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Hsp90 alpha/beta Antibody (YA356) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp90 alpha/beta.

HY-P81050

	Phospho-HSF1 (Ser326) Antibody(YA894) 1 Publications Verification HSF1; HSTF1; Heat shock factor protein 1; HSF 1; Heat shock transcription factor 1; HSTF 1	WB, IHC-P, IP	Human
	Phospho-HSF1 (Ser326) Antibody(YA894) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-HSF1 (Ser326).

HY-P86644

	Hsp90 beta Antibody (YA6336) HSP90AB1; HSP90B; HSPC2; HSPCB; Heat shock protein HSP 90-beta; HSP 90; Heat shock 84 kDa; HSP 84; HSP84	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Hsp90 beta Antibody (YA6336) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp90 beta.

HY-P80710

	Hsp40 Antibody (YA731) DNAJB1; DNAJ1; HDJ1; HSPF1; DnaJ homolog subfamily B member 1; DnaJ protein homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1	WB	Human
	Hsp40 Antibody (YA731) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp40.

HY-P80822

	Phospho-HSF1 (Ser303/Ser307) Antibody (YA188) HSF1; HSTF1; Heat shock factor protein 1; HSF 1; Heat shock transcription factor 1; HSTF 1	WB, IHC-P	Human
	Phospho-HSF1 (Ser303/Ser307) Antibody (YA188) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-HSF1 (Ser303/Ser307).

HY-P80710A

	Hsp40 Antibody (YA731)(PBS only) DNAJB1; DNAJ1; HDJ1; HSPF1; DnaJ homolog subfamily B member 1; DnaJ protein homolog 1; Heat shock 40 kDa protein 1; HSP40; Heat shock protein 40; Human DnaJ protein 1; hDj-1	WB	Human
	Hsp40 Antibody (YA731) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp40.

HY-P83003

	DNAJA1 Antibody (YA2748) DNAJA1; DNAJ2; HDJ2; HSJ2; HSPF4; DnaJ homolog subfamily A member 1; DnaJ protein homolog 2; HSDJ; Heat shock 40 kDa protein 4; Heat shock protein J2; HSJ-2; Human DnaJ protein 2; hDj-2	WB, FC, IP	Human, Mouse, Rat
	DNAJA1 Antibody (YA2748) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DNAJA1.

HY-P80711

	Hsp60 Antibody (YA730) HSPD1; HSP60; 60 kDa Heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein	WB, ICC/IF, IP	Human, Mouse, Rat
	Hsp60 Antibody (YA730) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Hsp60.

HY-P86546

	Hsp60 Antibody (YA6238) HSPD1; HSP60; 60 kDa Heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Hsp60 Antibody (YA6238) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp60.

HY-P80822A

	Phospho-HSF1 (Ser303/Ser307) Antibody (YA188)(PBS only) HSF1; HSTF1; Heat shock factor protein 1; HSF 1; Heat shock transcription factor 1; HSTF 1	WB, IHC-P	Human
	Phospho-HSF1 (Ser303/Ser307) Antibody (YA188) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-HSF1 (Ser303/Ser307).

HY-P86671

	phospho-HSF1 (Ser326) Antibody (YA6363) HSF1(S326); HSF1(phospho S326); p-HSF1(phospho S326); Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1; hsf1; HSTF 1; HSTF1; HSF1_HUMAN.	WB, IHC-P, IHC-F, ICC/IF, FC	Human, Mouse
	phospho-HSF1 (Ser326) Antibody (YA6363) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to phospho-HSF1 (Ser326).

HY-P80711A

	Hsp60 Antibody (YA730)(PBS only) HSPD1; HSP60; 60 kDa Heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein	WB, ICC/IF, IP	Human, Mouse, Rat
	Hsp60 Antibody (YA730) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Hsp60.

HY-P86671A

	phospho-HSF1 (Ser326) Antibody (YA6363)(PBS only) HSF1(S326); HSF1(phospho S326); p-HSF1(phospho S326); Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1; hsf1; HSTF 1; HSTF1; HSF1_HUMAN.	WB, IHC-P, IHC-F, ICC/IF, FC	Human, Mouse
	phospho-HSF1 (Ser326) Antibody (YA6363) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to phospho-HSF1 (Ser326).

HY-P86510

	GRP78 BiP Antibody (YA6202) 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca; 2+; -binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP;	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	GRP78 BiP Antibody (YA6202) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GRP78 BiP.

HY-P80696

	GRP78 BiP Antibody (YA746) HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP	WB, ICC/IF, IP	Human, Mouse, Rat
	GRP78 BiP Antibody (YA746) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to GRP78 BiP.

HY-P85741

	GRP78 BiP Antibody (YA5433) HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca; 2+; -binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP	WB, IHC-P, ICC/IF	Human, Rat
	GRP78 BiP Antibody (YA5433) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to GRP78 BiP.

HY-P83410

	Grp75/MOT Antibody (YA3155) HSPA9; GRP75; HSPA9B; Stress-70 protein; mitochondrial; 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74; PBP74	WB	Human, Mouse, Rat
	Grp75/MOT Antibody (YA3155) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Grp75/MOT.

HY-P80696A

	GRP78 BiP Antibody (YA746)(PBS only) HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP	WB, ICC/IF, IP	Human, Mouse, Rat
	GRP78 BiP Antibody (YA746) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to GRP78 BiP.

HY-P82868

	Hsp110 Antibody (YA2613) Antigen NY-CO-25; Heat shock protein 105 kDa; HS105; HSP105; HSP105A; HSP105B; HSP110; HSPH1	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Hsp110 Antibody (YA2613) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp110.

HY-P810454

	AHA1 Antibody AHSA1, C14orf3, HSPC322, Activator of 90 kDa Heat shock protein ATPase homolog 1, AHA1, p38	WB, IHC-P, IF-Tissue, ELISA	Human, Mouse
	AHA1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to AHA1.

HY-P82445

	Cpn10 Antibody (YA2190) HSPE1; 10 kDa Heat shock protein; mitochondrial; Hsp10; 10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Cpn10 Antibody (YA2190) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cpn10.

HY-P82278

	AHA1 Antibody (YA2023) AHSA1; C14orf3; HSPC322; Activator of 90 kDa Heat shock protein ATPase homolog 1; AHA1; p38	WB, IP	Human, Mouse, Rat
	AHA1 Antibody (YA2023) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AHA1.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-142980

DOPG Dioleoylphosphatidylglycerol		Phospholipids
DOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Heat shock protein

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Natural
Products