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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
Heparan
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "Heparan" in MCE Product Catalog:
23
Category:
Polysaccharides Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides
Target:
11
11 Cited Publications
Cat. No.: HY-P3160
CAS No.: 86088-83-7
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Research Areas:
Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans .
This product is a human Fibronectin obtained by recombinant expression in a rice expression system.
This product is a human Fibronectin obtained by recombinant expression in a rice expression system.
5
5 Cited Publications
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OGT 2115 is a potent, cell-permeable and orally active heparanase inhibitor with an IC50 of 0.4 μM. OGT 2115 has anti-angiogenic properties (IC50 of 1 μM). OGT 2115 also inhibits heparan sulfate degradation activity .
2
2 Cited Publications
Cat. No.: HY-122704A
CAS No.: 5424-37-3
Synonyms: Aminoquinuride dihydrochloride
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Surfen dihydrochloride is a potent heparan sulfate antagonist. Surfen inhibits FGF2 binding and signal transduction. Surfen binds to glycosaminoglycans and reduces tau hyperphosphorylation. Surfen dihydrochloride inhibits the activity of recombinant uronyl 2-O-sulfotransferase with an IC50 of approximately 2 μM. Surfen dihydrochloride inhibits HSV-1 viral infection. Surfen dihydrochloride inhibits neural differentiation, delays remyelination, and alleviates EAE .
1
1 Cited Publications
Cat. No.: HY-P70487
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPC3; SGB; Prev. SDYS; Glypican Proteoglycan 3; Glypican-3; GTR2-2; OCI-5; MXR7; SGBS1; Heparan Sulphate Proteoglycan; SGBS; Secreted Glypican-3; DGSX; OCI5; Glypican 3; Intestinal Protein OCI-5
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70507
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD44; Chondroitin Sulfate Proteoglycan 8; Prev. MDU2; Heparan Sulfate Proteoglycan; Prev. MDU3; Phagocytic Glycoprotein I; Prev. MIC4; Phagocyte Glycoprotein 1; HUTCH-I; In(Lu) Related-P80; CDw44; Soluble CD44; GP90 Lymphocyte Homing/Adhesion Receptor; EC
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P80062
Synonyms: LHR antibody;
BA-1 antibody;
CD 44 antibody;
CD44 antibody;
CD44 antigen antibody;
CD44 molecule (Indian blood group) antibody;
CD44 molecule antibody;
CD44_HUMAN antibody;
CDw44 antibody;
Cell surface glycoprotein CD44 antibody;
chondroitin sulfate proteoglycan 8 antibody;
CSPG8 antibody;
ECMR-III antibody;
Epican antibody;
Extracellular matrix receptor III antibody;
GP90 lymphocyte homing/adhesion receptor antibody;
HCELL antibody;
hematopoietic cell E- and L-selectin ligand antibody;
Heparan sulfate proteoglycan antibody;
Hermes antigen antibody;
homing function and Indian blood group system antibody;
HSA antibody;
HUTCH-I antibody;
HUTCH1 antibody;
Hyaluronate receptor antibody;
IN antibody;
MC56 antibody;
MDU2 antibody;
MDU3 antibody
Cat. No.: HY-P99797
CAS No.: 2140211-48-7
Synonyms: JR-141
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Cat. No.: HY-P990841
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Cat. No.: HY-P2955
CAS No.: 149371-12-0
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Heparinase II is a glycosidase targeting heparin and heparan sulfate. Heparinase II is promising for research of glycosaminoglycan structure-function analysis, anticoagulant agents and tumor microenvironment modulation .
Cat. No.: HY-P2953
CAS No.: 37290-86-1
Synonyms: Heparinase III
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Research Areas:
Heparitin sulfate lyase (Heparinase III) is a glycosidic lyase targeting heparan sulfate and heparin. Heparitin sulfate lyase is promising for research of low-molecular-weight heparin production and cancers .
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BODIPY FL hydrazide is a BODIPY-containing hydrazide fluorescent dye. BODIPY FL hydrazide is used to label carbonyl groups on oxidatively damaged proteins, 3-ketosteroids, and heparin/heparan sulfate carbohydrates. BODIPY FL hydrazide specifically binds to protein carbonyls, steroid keto groups, or reducing-end carbonyls of carbohydrates through derivatization or reductive amination via its hydrazide group to form stable conjugates; after the reaction is complete, the labeled molecules emit strong fluorescence (Ex/Em = 488-495/516-520 nm) .
Cat. No.: HY-163388
CAS No.: 2982257-63-4
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Research Areas:
CHI3L1-IN-2 (Compound 36) is a CHI3L1 (Chitinase-3-Like Protein 1) inhibitor. CHI3L1-IN-2 inhibits the? interaction between CHI3L1 and heparan sulfate (CHI3L1:HSIII), with an IC50 of 26 nM. CHI3L1, also known as YKL-40, is a glycoprotein associated with inflammation, fibrosis, and cancer .
Cat. No.: HY-D1632
CAS No.: 460085-45-4
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4-MU-α-GlcNS sodium is a fluorogenic substrate for heparan sulfate sulfamidase, with apparent Km values of 4 mM and 8 mM for fibroblast and leukocyte enzymes, respectively. 4-MU-α-GlcNS sodium undergoes enzymatic desulfation to generate an intermediate, which requires a second incubation with yeast α-glucosidase to hydrolyze and release 4-methylumbelliferone, detected by fluorescence at Ex/Em = 365/450 nm. 4-MU-α-GlcNS sodium is suitable for fibroblast homogenates, leukocytes, and dried leukocyte filter paper samples, and can be used for the detection and study of enzyme activity in mucopolysaccharidosis type IIIA .
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Surfen is a potent heparan sulfate antagonist. Surfen inhibits FGF2 binding and signal transduction. Surfen binds to glycosaminoglycans and reduces tau hyperphosphorylation. Surfen inhibits the activity of recombinant uronyl 2-O-sulfotransferase with an IC50 of approximately 2 μM. Surfen inhibits HSV-1 viral infection. Surfen inhibits neural differentiation, delays remyelination, and alleviates EAE .
Cat. No.: HY-P3795
CAS No.: 361443-81-4
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Research Areas:
Cat. No.: HY-P99694
CAS No.: 2396411-71-3
Synonyms: JR-171
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Cat. No.: HY-P991039
CAS No.: 2937458-25-6
Synonyms: AT-02
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
