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Homocysteine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (3) Apoptosis (18) Bacterial (1) Biochemical Assay Reagents (9) Caspase (14) Cathepsin (3) CHIKV (1) DNA Methyltransferase (2) Drug Derivative (1) Drug Intermediate (1) Endogenous Metabolite (37) Estrogen Receptor/ERR (1) Exosomes (1) Ferroptosis (1) Fluorescent Dye (5) Glutathione Peroxidase (1) HBV (1) Isotope-Labeled Compounds (13) Liposome (3) MOFs (1) NADPH Oxidase (1) Nucleoside Antimetabolite/Analog (16) Orexin Receptor (OX Receptor) (1) PARP (1) Phospholipase (1) Reactive Oxygen Species (ROS) (2) Reference Standards (8) SARS-CoV (1) Sigma Receptor (1) Sirtuin (1) TRP Channel (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (13) Endocrinology (15) Infection (5) Inflammation/Immunology (9) Metabolic Disease (28) Neurological Disease (6)
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Oligonucleotides:	Adenosine (2) Nucleoside Analogs (2) Cationic Lipids (3)

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Click Chemistry

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010347

L-Homocysteine Maximum Cited Publications 7 Publications Verification	Endogenous Metabolite Cathepsin	Cardiovascular Disease Inflammation/Immunology
L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia .

HY-W040329

2'-Deoxyadenosine	Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis	Metabolic Disease Endocrinology Cancer
2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

HY-W009749

L-Cystathionine 1 Publications Verification	Endogenous Metabolite Apoptosis	Cardiovascular Disease
L-Cystathionine is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine plays an important role in cardiovascular protection .

HY-W010347S

*DL-Homocysteine-d4*	Endogenous Metabolite	Inflammation/Immunology
DL-Homocysteine-d₄ is the deuterium labeled DL-Homocysteine. DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain .

HY-W040821

DL-Homocysteine 4 Publications Verification	Endogenous Metabolite	Neurological Disease
DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity .

HY-150097

Recombinant Human Serum Albumin(rHSA)	Biochemical Assay Reagents	Metabolic Disease Inflammation/Immunology Cancer
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .

HY-119323

7-Azido-4-methylcoumarin 1 Publications Verification	Fluorescent Dye	Others
7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H₂S). In the presence of H₂S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H₂S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .

HY-W011683

2'-Deoxyadenosine monohydrate	Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis	Metabolic Disease Endocrinology Cancer
2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-120380

FeTMPyP	MOFs PARP	Neurological Disease
FeTMPyP is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. FeTMPyP inhibits cell death, nitrotyrosine formation, and depolarization of mitochondrial transmembrane potential. FeTMPyP reduces homocysteine-induced nitrosative stress and partially restores TFEB protein and mRNA levels. FeTMPyP improves functional and behavioral deficits caused by chronic constriction injury in rats. FeTMPyP alleviates acute cerebral infarction in a rat model of middle cerebral artery occlusion with mild hyperglycemia. FeTMPyP can be used in studies related to neuropathic pain, renal aging, ischemic penumbra, and hyperglycemic stroke .

HY-101404A

*L-Homocysteine* thiolactone hydrochloride**	Amino Acid Derivatives	Cardiovascular Disease Inflammation/Immunology
L-Homocysteine thiolactone hydrochloride is an intramolecular thioester of Homocysteine. Homocysteine thiolactone hydrochloride prevents translational incorporation of homocysteine into proteins. L-Homocysteine thiolactone hydrochloride can induce elevated HHcy (hyperhomocysteinemia) in mice .

HY-W653733

*L-Homocysteine-d4* 1 Publications Verification	Isotope-Labeled Compounds Endogenous Metabolite Cathepsin	Cardiovascular Disease Inflammation/Immunology
L-Homocysteine-d₄ is deuterium labeled L-Homocysteine (HY-W010347) . L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia

HY-W048918

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-homocysteine	Amino Acid Derivatives	Others
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-homocysteine is a cysteine derivative .

HY-P5381

gp91 ds-tat 1 Publications Verification	NADPH Oxidase Ferroptosis Reactive Oxygen Species (ROS) Glutathione Peroxidase TRP Channel	Cardiovascular Disease Neurological Disease Inflammation/Immunology
gp91 ds-tat, a biological active peptide, is a NADPH oxidase 2 (Nox2) inhibitor. gp91 ds-tat blocks NADPH oxidase-dependent superoxide production. gp91 ds-tat ameliorates high glucose-induced increase in total ROS, LPOs and iron levels. gp91 ds-tat inhibits homocysteine (Hcy)-induced activation of NLRP3 inflammasomes and restores Hcy-inhibited lysosomal TRPML1 channel activity. gp91 ds-tat improves cerebrovascular and cognitive function in APP/PS1 mice. gp91 ds-tat can be used for the study of Alzheimer’s disease (AD), glomerular inflammation and cardiovascular disease .

HY-W011690

L-Homocystine	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.

HY-17557

Calcium N5-methyltetrahydrofolate Maximum Cited Publications 9 Publications Verification NSC173328; 5-Methyl THF calcium	Drug Derivative	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Calcium N5-methyltetrahydrofolate (NSC173328; 5-Methyl THF (calcium)), Levomefolic acid (HY-14781) derivative, is a folic acid supplement. Calcium N5-methyltetrahydrofolate can be used for the research of neural tube defects, infertility, non-hodgkin's lymphoma, endometriosis .

HY-W009390

DL-Homocystine	Endogenous Metabolite	Metabolic Disease
DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia.

HY-149048

Adenosylhomocysteinase SAHH; AHCY	Exosomes Endogenous Metabolite HBV	Infection Metabolic Disease
Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients .

HY-101404

*DL-Homocysteine* thiolactone hydrochloride**	Endogenous Metabolite	Others
DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-126426

CBHcy	DNA Methyltransferase	Cardiovascular Disease
CBHcy is an inhibitor for betaine-homocysteine S-methyltransferase (BGMT), with an IC₅₀ of 0.09 μM. CBHcy upregulates the plasma total homocysteine and causes transient hyperhomocysteinemia in mice model .

HY-W105506

Dimethylpropiothetin hydrochloride s,s-Dimethyl-β-propionic acid thetine	Drug Intermediate	Others
Dimethylpropiothetin hydrochloride is a dimethylsulfide precursor. Dimethylpropiothetin hydrochloride can be isolated from the marine coccolithophore Hymenomonas carterae. Dimethylpropiothetin hydrochloride participates in the maintenance of cellular osmotic pressure .

HY-P1341

OXA(17-33) Orexin A (17-33) (human, mouse, rat, bovine)	Orexin Receptor (OX Receptor) Sigma Receptor Phospholipase	Neurological Disease
OXA (17-33) (Orexin A (17-33) (human, mouse, rat, bovine)) is the shortest active orexin peptide that selectively targets OX1 (EC₅₀=8.29 nM), with 23-fold selectivity for the OX1 receptor over the OX2 receptor. The activity of OXA (17-33) depends on the Tyr17, Leu20, Asn25, His26 residues and the spatial conformation of the α-helix. OXA (17-33) activates signaling pathways involving inositol-1,4,5-trisphosphate receptor (IP3R), phospholipase D (PL-D) and choline-Sigma-1R, thereby increasing the cytoplasmic Ca ²⁺ level in nucleus accumbens neurons, an effect that is blocked by Sigma-1R antagonists. OXA (17-33) serves as an important biological probe for investigating the function of the OX1 receptor. OXA (17-33) can be modified via incorporation of mixed disulfide bonds of homocysteine and cysteamine, and is widely used in studies related to insomnia and narcolepsy .

HY-W010347R

*L-Homocysteine* (Standard)**	Reference Standards Endogenous Metabolite Cathepsin	Cardiovascular Disease Inflammation/Immunology
L-Homocysteine (Standard) is the analytical standard of L-Homocysteine. This product is intended for research and analytical applications. L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2].

HY-W009749C

L-Cystathionine dihydrochloride 1 Publications Verification	Endogenous Metabolite Apoptosis	Cardiovascular Disease
L-Cystathionine (dihydrochloride) is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine (dihydrochloride) protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine (dihydrochloride) plays an important role in cardiovascular protection .

HY-158779

Sulfane sulfur probe 4 SSP4	Fluorescent Dye	Others
Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (E_x/E_m=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe ²⁺, Fe ³⁺, Mg ²⁺, Ca ²⁺, and Zn ²⁺) .

HY-D2315

Probe-Cys	Fluorescent Dye	Cancer
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cysteine (Cys) (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant DTT (HY-15917) and the NEM (HY-D0843) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .

HY-W040329R

2'-Deoxyadenosine (Standard)	Reference Standards Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis	Metabolic Disease Endocrinology Cancer
2'-Deoxyadenosine (Standard) is the analytical standard of 2'-Deoxyadenosine (HY-W040329). This product is intended for research and analytical applications. 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

HY-W011690S

L-Homocystine-d8	Endogenous Metabolite	Metabolic Disease
L-Homocystine-d₈ is the deuterium labeled L-Homocystine. L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.

HY-D1423

Dibromobimane	Fluorescent Dye	Others
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .

HY-E70079

Cystathionine β-lyase, Recombinant Microorganisms CBL	Biochemical Assay Reagents	Infection
Cystathionine β-lyase, Recombinant Microorganisms (CBL) is an enzyme that catalyzes the breakdown of cystathionine to homocysteine, the penultimate step in methionine biosynthesis. Cystathionine β-lyase is important for bacterial virulence .

HY-E70078

Cystathionine β-synthase	Biochemical Assay Reagents	Others
Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H₂S) .

HY-W040329S1

2'-Deoxyadenosine-13C10	Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis	Metabolic Disease Endocrinology Cancer
2'-Deoxyadenosine- ¹³C₁₀ is ¹³C-labeled 2'-Deoxyadenosine (HY-W040329) ^{. 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer ^.}

HY-W009390S

DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8	Endogenous Metabolite	Metabolic Disease
DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d₈ is the deuterium labeled DL-Homocystine. DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia .

HY-133135

CHIKV-IN-1	CHIKV Nucleoside Antimetabolite/Analog	Infection
CHIKV-IN-1 (Compound 3a) is a compound that inhibits the Chikungunya virus (CHIKV) with an EC₅₀ of 0.12 μM. CHIKV-IN-1 is a potent inhibitor of the S-adenosyl-L-homocysteine hydrolase (SAH hydrolase), with an IC₅₀ of 0.36 μM. CHIKV-IN-1 is only effective against CHIKV and some other alphaviruses, but has no activity against other RNA viruses such as SARS-CoV, MERS-CoV, and ZIKV. CHIKV-IN-1 has extremely low cytotoxicity (CC₅₀ > 250 μM), and it has an extremely high selectivity index (SI > 2083). CHIKV-IN-1 can be used in research on anti-Chikungunya virus .

HY-W011683S6

2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate	Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis	Metabolic Disease Endocrinology Cancer
2'-Deoxyadenosine monohydrate- ¹³C₁₀, ¹⁵N₅ is the ¹³C and ¹⁵N labeled 2'-Deoxyadenosine monohydrate (HY-W011683) . 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-N10083

Selaginellin	Reactive Oxygen Species (ROS) Sirtuin	Cancer
Selaginellin is an inhibitor of Reactive Oxygen Species and an activator of SIRT1. Selaginellin protects endothelial cells against homocysteine-induced senescence by inhibitng reactive oxygen species and upregulating SIRT1 gene expression .

HY-106256

HMR-3339	Estrogen Receptor/ERR	Metabolic Disease Endocrinology
HMR-3339 is a new selective estrogen receptor modulator. HMR-3339 reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine. HMR-3339 corrects bone alterations induced by ovariectomy .

HY-W011683S3

2'-Deoxyadenosine monohydrate-5′-13C	Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis	Metabolic Disease Endocrinology Cancer
2'-Deoxyadenosine monohydrate-5′- ¹³C is the ¹³C labeled 2'-Deoxyadenosine monohydrate (HY-W011683) . 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-W011683S

2'-Deoxyadenosine monohydrate-1′-13C	Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis	Metabolic Disease Endocrinology Cancer
2'-Deoxyadenosine monohydrate-1′- ¹³C is the ¹³C labeled 2'-Deoxyadenosine monohydrate (HY-W011683) . 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-101404R

*DL-Homocysteine* thiolactone hydrochloride (Standard)**	Reference Standards Endogenous Metabolite	Others
DL-Homocysteine thiolactone (hydrochloride) (Standard) is the analytical standard of DL-Homocysteine thiolactone (hydrochloride). This product is intended for research and analytical applications. DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-101404S

*DL-Homocysteine* thiolactone-d4 hydrochloride**	Isotope-Labeled Compounds Endogenous Metabolite	Others
DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-W141788

*N-Butyryl-DL-homocysteine* thiolactone**	Bacterial	Infection
N-Butyryl-DL-homocysteine thiolactone is an N-acyl homoserine lactone (AHL) analogue. AHLs are potent inhibitors of biofilm formation and virulence factors, and has been used for degrading microbial communities, reducing bacterial pathogenicity .

HY-135043

S-Aristeromycinyl-L-homocysteine	DNA Methyltransferase	Others
S-Aristeromycinyl-L-homocysteine is an S-adenosylmethionine-dependent methyltransferase inhibitor .

HY-E70345

Homocysteine methyltransferase	Endogenous Metabolite	Others
Homocysteine methyltransferase is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-126470A

*N-Palmitoyl homocysteine* (PHC) ammonium** PHCPamHcy	Biochemical Assay Reagents	Others
N-Palmitoyl homocysteine (PHC) ammonium is a pH sensitive lipid hat is cleaved under endosomal pH conditions (pH 5.5) .

HY-116762

*N-butyryl-L-Homocysteine* thiolactone**	Biochemical Assay Reagents	Others
Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. The control of bacterial infection by quenching the quorum sensing system of bacteria is a promising research area. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR protein family, is coordinated by the synthesis of diffusible acyl homoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, a small, diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism . N-butyryl-L-homocysteine thiolactone induces violacein expression in Viola viola mutants that normally fail to produce AHL.

HY-W009749R

L-Cystathionine (Standard)	Reference Standards Endogenous Metabolite Apoptosis	Cardiovascular Disease
L-Cystathionine is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine plays an important role in cardiovascular protection .

HY-W040821R

*DL-Homocysteine* (Standard)**	Reference Standards Endogenous Metabolite	Neurological Disease
Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .

HY-W800720

S-(Pyridin-2-ylthio)-L-homocysteine	Biochemical Assay Reagents	Others
(S)-2-amino-4-(2-(pyridin-2-yl)disulfanyl)butanoic acid is a small molecule reagent with a 2-thiopyridine linked to a short amino acid. SPDP is a thiol-specific labeling reagent, commonly used in reversibly binding cysteine residues on proteins. The disulfide bond it forms with the cysteine is selectively cleaved in the reducing environment of the cell cytoplasm.

HY-137802

SAHO2 S-Adenosyl-L-Homocysteine sulfone	Amino Acid Derivatives	Others
SAHO2 is the sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride (SAM) and serves as a substrate for radical SAM enzymes .

HY-W423489

SARS-CoV-2-IN-76 S-Adenosyl-DL-Homocysteine	SARS-CoV	Infection
SARS-CoV-2-IN-76 (compound 1) is a nsp14-viral cap N7 methyltranferase and PLpro inhibitor of severe acute respiratory syndrome corona virus (SARS-CoV-2) .

Cat. No.	Product Name	Type

HY-158779

Sulfane sulfur probe 4

SSP4

Fluorescent Dye

Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (E_x/E_m=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe ²⁺, Fe ³⁺, Mg ²⁺, Ca ²⁺, and Zn ²⁺) .

HY-D2315

Probe-Cys

Fluorescent Dye

Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cysteine (Cys) (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant DTT (HY-15917) and the NEM (HY-D0843) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .

HY-D1423

Dibromobimane	Fluorescent Dye
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .

Cat. No.	Product Name	Type

HY-150097

Recombinant Human Serum Albumin(rHSA)

Biochemical Assay Reagents

Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .

HY-116762

N-butyryl-L-Homocysteine thiolactone

Biochemical Assay Reagents

Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. The control of bacterial infection by quenching the quorum sensing system of bacteria is a promising research area. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR protein family, is coordinated by the synthesis of diffusible acyl homoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, a small, diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism . N-butyryl-L-homocysteine thiolactone induces violacein expression in Viola viola mutants that normally fail to produce AHL.

Cat. No.	Product Name	Target	Research Area

HY-W048918

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-homocysteine	Amino Acid Derivatives	Others
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-homocysteine is a cysteine derivative .

HY-P5381

gp91 ds-tat 1 Publications Verification	NADPH Oxidase Ferroptosis Reactive Oxygen Species (ROS) Glutathione Peroxidase TRP Channel	Cardiovascular Disease Neurological Disease Inflammation/Immunology
gp91 ds-tat, a biological active peptide, is a NADPH oxidase 2 (Nox2) inhibitor. gp91 ds-tat blocks NADPH oxidase-dependent superoxide production. gp91 ds-tat ameliorates high glucose-induced increase in total ROS, LPOs and iron levels. gp91 ds-tat inhibits homocysteine (Hcy)-induced activation of NLRP3 inflammasomes and restores Hcy-inhibited lysosomal TRPML1 channel activity. gp91 ds-tat improves cerebrovascular and cognitive function in APP/PS1 mice. gp91 ds-tat can be used for the study of Alzheimer’s disease (AD), glomerular inflammation and cardiovascular disease .

HY-P1341

OXA(17-33) Orexin A (17-33) (human, mouse, rat, bovine)	Orexin Receptor (OX Receptor) Sigma Receptor Phospholipase	Neurological Disease
OXA (17-33) (Orexin A (17-33) (human, mouse, rat, bovine)) is the shortest active orexin peptide that selectively targets OX1 (EC₅₀=8.29 nM), with 23-fold selectivity for the OX1 receptor over the OX2 receptor. The activity of OXA (17-33) depends on the Tyr17, Leu20, Asn25, His26 residues and the spatial conformation of the α-helix. OXA (17-33) activates signaling pathways involving inositol-1,4,5-trisphosphate receptor (IP3R), phospholipase D (PL-D) and choline-Sigma-1R, thereby increasing the cytoplasmic Ca ²⁺ level in nucleus accumbens neurons, an effect that is blocked by Sigma-1R antagonists. OXA (17-33) serves as an important biological probe for investigating the function of the OX1 receptor. OXA (17-33) can be modified via incorporation of mixed disulfide bonds of homocysteine and cysteamine, and is widely used in studies related to insomnia and narcolepsy .

HY-W141788

*N-Butyryl-DL-homocysteine* thiolactone**	Bacterial	Infection
N-Butyryl-DL-homocysteine thiolactone is an N-acyl homoserine lactone (AHL) analogue. AHLs are potent inhibitors of biofilm formation and virulence factors, and has been used for degrading microbial communities, reducing bacterial pathogenicity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010347

L-Homocysteine Maximum Cited Publications 7 Publications Verification	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite Cathepsin
L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia .

HY-W040329

2'-Deoxyadenosine	Natural Products Immune System Disorder Classification of Application Fields Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis
2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

HY-W009749

L-Cystathionine 1 Publications Verification	Cardiovascular Disease Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Disease markers Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Apoptosis
L-Cystathionine is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine plays an important role in cardiovascular protection .

HY-W040821

DL-Homocysteine 4 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Source Classification	Endogenous Metabolite
DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity .

HY-W011683

2'-Deoxyadenosine monohydrate	Natural Products Microorganisms Other Diseases Disease Research Fields Source Classification	Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis
2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-W011690

L-Homocystine	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.

HY-W009390

DL-Homocystine	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia.

HY-149048

Adenosylhomocysteinase SAHH; AHCY	Infection Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Exosomes Endogenous Metabolite HBV
Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients .

HY-101404

*DL-Homocysteine* thiolactone hydrochloride**	Classification of Application Fields Other Diseases Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-W105506

Dimethylpropiothetin hydrochloride s,s-Dimethyl-β-propionic acid thetine	Structural Classification Natural Products Gramineae Marine natural products Sporobolus anglicus (C.E.Hubb.) P.M.Peterson & Saarela Plants Source Classification	Drug Intermediate
Dimethylpropiothetin hydrochloride is a dimethylsulfide precursor. Dimethylpropiothetin hydrochloride can be isolated from the marine coccolithophore Hymenomonas carterae. Dimethylpropiothetin hydrochloride participates in the maintenance of cellular osmotic pressure .

HY-W010347R

*L-Homocysteine* (Standard)**	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Cathepsin
L-Homocysteine (Standard) is the analytical standard of L-Homocysteine. This product is intended for research and analytical applications. L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2].

HY-W009749C

L-Cystathionine dihydrochloride 1 Publications Verification	Cardiovascular Disease Classification of Application Fields Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Apoptosis
L-Cystathionine (dihydrochloride) is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine (dihydrochloride) protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine (dihydrochloride) plays an important role in cardiovascular protection .

HY-W040329R

2'-Deoxyadenosine (Standard)	Structural Classification Natural Products Immune System Disorder Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis
2'-Deoxyadenosine (Standard) is the analytical standard of 2'-Deoxyadenosine (HY-W040329). This product is intended for research and analytical applications. 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

HY-N10083

Selaginellin	Phenols Polyphenols Selaginella sinensis (Desv.) Spring Selaginellaceae Plants Source Classification	Reactive Oxygen Species (ROS) Sirtuin
Selaginellin is an inhibitor of Reactive Oxygen Species and an activator of SIRT1. Selaginellin protects endothelial cells against homocysteine-induced senescence by inhibitng reactive oxygen species and upregulating SIRT1 gene expression .

HY-101404R

*DL-Homocysteine* thiolactone hydrochloride (Standard)**	Structural Classification Amino acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
DL-Homocysteine thiolactone (hydrochloride) (Standard) is the analytical standard of DL-Homocysteine thiolactone (hydrochloride). This product is intended for research and analytical applications. DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-126470A

*N-Palmitoyl homocysteine* (PHC) ammonium** PHCPamHcy	Lipid	Biochemical Assay Reagents
N-Palmitoyl homocysteine (PHC) ammonium is a pH sensitive lipid hat is cleaved under endosomal pH conditions (pH 5.5) .

HY-W009749R

L-Cystathionine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Disease markers Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Apoptosis
L-Cystathionine is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine plays an important role in cardiovascular protection .

HY-W040821R

*DL-Homocysteine* (Standard)**	Structural Classification Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder Source Classification	Reference Standards Endogenous Metabolite
Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .

HY-W011683R

2'-Deoxyadenosine monohydrate (Standard)	Natural Products Microorganisms Source Classification	Reference Standards Endogenous Metabolite Nucleoside Antimetabolite/Analog Caspase Apoptosis
2'-Deoxyadenosine monohydrate (Standard) is the analytical standard of 2'-Deoxyadenosine monohydrate ((HY-W011683). This product is intended for research and analytical applications. 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-180776

S-Inosyl-L-homocysteine	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
S-Inosyl-L-homocysteine is a nucleoside metabolite.

HY-W011690R

L-Homocystine (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
L-Homocystine (Standard) is the analytical standard of L-Homocystine (HY-W011690). This product is intended for research and analytical applications. L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.

HY-W009749CR

L-Cystathionine dihydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Apoptosis
L-Cystathionine dihydrochloride (Standard) is the analytical standard of L-Cystathionine dihydrochloride (HY-W009749C). This product is intended for research and analytical applications. L-Cystathionine dihydrochloride is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine dihydrochloride protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs). L-Cystathionine dihydrochloride plays an important role in cardiovascular protection.

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P72073

	AHCY Protein, Human (His-SUMO) Adenosylhomocysteinase; AdoHcyase; ahcY; S adenosyl L Homocysteine hydrolase; S adenosylHomocysteine hydrolase; S-adenosyl-L-Homocysteine hydrolase; SAHH; SAHH_HUMAN	Human	E. coli
	AHCY Protein, Human (His-SUMO) is a key cellular enzyme to catalyze the breakdown of S-adenosylhomocysteine (AdoHcy) to homocysteine and adenosine. AHCY Protein, Human is a regulator of biological transmethylation in general.

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Species
Source
Tag
Accession
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Cat. No.	Product Name	Chemical Structure

HY-W010347S

*DL-Homocysteine-d4*
DL-Homocysteine-d₄ is the deuterium labeled DL-Homocysteine. DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain .

HY-W653733

*L-Homocysteine-d4* 1 Publications Verification
L-Homocysteine-d₄ is deuterium labeled L-Homocysteine (HY-W010347) . L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia

HY-W011690S

L-Homocystine-d8
L-Homocystine-d₈ is the deuterium labeled L-Homocystine. L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.

HY-W040329S1

2'-Deoxyadenosine-13C10

2'-Deoxyadenosine- ¹³C₁₀ is ¹³C-labeled 2'-Deoxyadenosine (HY-W040329) ^{. 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer ^.}

HY-W009390S

DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d8
DL-Homocystine-3,3,3’,3’,4,4,4’,4’-d₈ is the deuterium labeled DL-Homocystine. DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia .

HY-W011683S6

2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate

2'-Deoxyadenosine monohydrate- ¹³C₁₀, ¹⁵N₅ is the ¹³C and ¹⁵N labeled 2'-Deoxyadenosine monohydrate (HY-W011683) . 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-W011683S3

2'-Deoxyadenosine monohydrate-5′-13C

2'-Deoxyadenosine monohydrate-5′- ¹³C is the ¹³C labeled 2'-Deoxyadenosine monohydrate (HY-W011683) . 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-W011683S

2'-Deoxyadenosine monohydrate-1′-13C

2'-Deoxyadenosine monohydrate-1′- ¹³C is the ¹³C labeled 2'-Deoxyadenosine monohydrate (HY-W011683) . 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-101404S

*DL-Homocysteine* thiolactone-d4 hydrochloride**
DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-W778207

2'-Deoxyadenosine-13C5 monohydrate

2'-Deoxyadenosine- ¹³C₅ monohydrate is the ¹³C labeled isotope of '-Deoxyadenosine monohydrate (HY-W040329). 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

HY-W745905

2'-Deoxyadenosine-15N1

2'-Deoxyadenosine- ¹⁵N₁ is the ¹⁵N-labeled 2'-Deoxyadenosine (HY-W040329). 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

HY-W011683S7

2'-Deoxyadenosine monohydrate-15N5

2'-Deoxyadenosine monohydrate- ¹⁵N₅ is the ¹⁵N labeled 2'-Deoxyadenosine monohydrate (HY-W011683) . 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-W011683S1

2'-Deoxyadenosine monohydrate-2′-13C

2'-Deoxyadenosine monohydrate-2′- ¹³C is the ¹³C labeled 2'-Deoxyadenosine monohydrate(HY-W011683) . 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-W040329S

2'-Deoxyadenosine-13C10,15N5

2'-Deoxyadenosine- ¹³C₁₀, ¹⁵N₅ is ¹³C and ¹⁵N-labeled 2'-Deoxyadenosine (HY-W040329) . 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

HY-W011683S2

2'-Deoxyadenosine monohydrate-3′-13C
2'-Deoxyadenosine monohydrate-3′- ¹³C is the ¹³C labeled 2'-Deoxyadenosine monohydrate (HY-W011683) ^{caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer>}

HY-W040329S3

2'-Deoxyadenosine-15N5,d13

2'-Deoxyadenosine- ¹⁵N₅,d₁₃ is deuterium and ¹⁵N labeled 2'-Deoxyadenosine (HY-W040329) . 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

Host:	Mouse (1) Rabbit (2)
Reactivity:	Human (3) Rat (2) Mouse (2)
Application:	IHC-P (3) ICC/IF (1) IP (1) WB (3) FC (1)
Isotype:	IgG (2) IgG2a (1)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (3) Recombinant (2)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82804

	BHMT Antibody (YA2549) BHMT; Betaine--Homocysteine S-methyltransferase 1	WB, IHC-P, IP	Human
	BHMT Antibody (YA2549) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to BHMT.

HY-P85053

	BHMT Antibody (YA4745) BHMT; Betaine--Homocysteine S-methyltransferase 1	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	BHMT Antibody (YA4745) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to BHMT.

HY-P87063

	SAHH Antibody(YA6756) Adenosylhomocysteinase antibody; AdoHcyase antibody; ahcY antibody; S adenosyl L Homocysteine hydrolase antibody; S adenosylHomocysteine hydrolase antibody; S-adenosyl-L-Homocysteine hydrolase antibody; SAHH antibody; SAHH_HUMAN antibody;	WB, IHC-P	Human, Mouse, Rat
	SAHH Antibody(YA6756) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SAHH.

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Cat. No.	Product Name		Classification

HY-119323

7-Azido-4-methylcoumarin 1 Publications Verification		Labeling and Fluorescence Imaging Azide
7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H₂S). In the presence of H₂S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H₂S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .

Cat. No.	Product Name		Classification

HY-W040329

2'-Deoxyadenosine		Nucleoside Analogs Adenosine
2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer .

HY-W011683

2'-Deoxyadenosine monohydrate		Nucleoside Analogs Adenosine
2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of *S-adenosyl-L-homocysteine* hydrolase (SAHH)**. 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer .

HY-172925

CP-LC-1447		Cationic Lipids
CP-LC-1447 is an ionizable cationic amino lipid derived from homocysteine.

HY-W1130407

CP-LC-1073		Cationic Lipids
CP-LC-1073 is a specific ionizable cationic amino lipid derived from the amino acid homocysteine. CP-LC-1073 can used in lipid nanoparticle (LNP) formulations for efficient in vivo delivery and expression of RNA (mRNA, cRNA, saRNA).

HY-176027

CP-LC-1422		Cationic Lipids
CP-LC-1422 is a homocysteine-derived ionizable amino lipid with high RNA delivery capability and can mediate high-level protein expression in vivo. CP-LC-1422 exhibits significant spleen targeting via intravenous injection in a lipid nanoparticle (LNP) formulation with no significant toxicity observed .

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