43 Results for "

IL-33

" in MedChemExpress (MCE) Product Catalog:
Products (43)

43 Results for "IL-33" in MCE Product Catalog:

14
14 Publications Verification
Art. -Nr.: HY-P7218
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuIL-33; IL33
Species:  
Source:  
loading...
    loading...
4
4 Cited Publications
Art. -Nr.: HY-P7041
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-33; IL-1F11; NF-HEV; DVS 27
Species:  
Source:  
loading...
    loading...
3
3 Cited Publications
Art. -Nr.: HY-P99444
CAS. Nr.: 2173054-79-8
Synonyms: MSTT 1041A; RG 6149
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1α, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P99673
CAS. Nr.: 2226742-52-3
Synonyms: REGN-3500; SAR-440340

Forschungsgebiete:  

Inflammation/Immunology

Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma, chronic obstructive pulmonary disease (COPD), and atopic dermatitis (AD) .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P73210
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; IL-1F11; NF-HEV; DVS 27
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P70475
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; Interleukin-1 FamILy Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P70475AF
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; Interleukin-1 FamILy Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV
Species:  
Source:  
loading...
    loading...
Art. -Nr.: HY-P2729
CAS. Nr.: 9014-01-1
Synonyms: EC 3.4.21.14
Subtilisin (EC 3.4.21.14) is a bacterial serine protease. Subtilisin induces Apoptosis. Subtilisin stimulates the expression of pro-allergic cytokines (IL-1α, IL-33). Subtilisin induces prototypic allergic lung inflammation. Subtilisin exhibits anticancer activity against breast and colon cancer. Subtilisin shows antifouling activity. Subtilisin can be used as a detergent additive .
loading...
    loading...
Art. -Nr.: HY-P991267

Target:  

Interleukin Related

Forschungsgebiete:  

Inflammation/Immunology

CAN10 is is a humanized monoclonal antibody inhibitor targeting interleukin 1RAP (IL1RAP). CAN10 blocks IL-1, IL-33, and IL-36 signalling by targeting IL1RAP, preventing downstream proinflammatory and profibrotic responses. CAN10 reduces dermal and pulmonary fibrosis. CAN10 can be used for the research of immune system diseases, such as systemic sclerosis .
loading...
    loading...
Art. -Nr.: HY-150207
CAS. Nr.: 2360853-16-1
Reinheit:  99.24%
Target:  

PARP

Forschungsgebiete:  

Inflammation/Immunology

RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM. RBN-3143 inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines. RBN-3143 can be used in research of lung inflammation .
loading...
    loading...
Art. -Nr.: HY-P99018
CAS. Nr.: 2022981-44-6
Synonyms: Antibody ANB 020

Target:  

Interleukin Related

Forschungsgebiete:  

Inflammation/Immunology

Etokimab (Antibody ANB 020) is a humanized monoclonal antibody that targets IL-33. Etokimab can be used for the research of atopic dermatitis .
loading...
    loading...
Art. -Nr.: HY-168532
CAS. Nr.: 3099811-61-4
Target:  

Interleukin Related

Forschungsgebiete:  

Inflammation/Immunology

ST2-IN-1 is a ST2 inhibitor. ST2-IN-1 blocks the binding interaction between ST2 and IL-33, thereby attenuating the downstream ST2/IL-33 signaling pathway. ST2-IN-1 reduces IL-1β release from mast cells and alleviates ST2 upregulation in cells. ST2-IN-1 can be used for research on inflammatory and immune-related diseases .
loading...
    loading...
Art. -Nr.: HY-114354
CAS. Nr.: 302795-84-2
Reinheit:  98.41%
Synonyms: BOD FL alkyne
BODIPY (BOD) FL alkyne is an alkyne-containing BODIPY fluorophore derivative. BODIPY FL alkyne is a bioorthogonal labeling reagent with low toxicity and extremely low non-specific reactivity, and it is widely used in fluorescent bioimaging. BODIPY FL alkyne specifically labels azide groups on intracellular glycoconjugates mainly via strain-promoted azide-alkyne cycloaddition (SPAAC), or mediates site-specific conjugation with proteins such as IL-33, and supports positive cross-linking with other probes (e.g., DBCO-SCy5) for dual labeling. With the advantages of high specificity and low background interference, BODIPY FL alkyne can be used in the research of related diseases such as asthma, atopic dermatitis and inflammatory bowel disease .
loading...
    loading...
Art. -Nr.: HY-P990669
CAS. Nr.: 2241728-76-5

Target:  

Interleukin Related

Forschungsgebiete:  

Inflammation/Immunology

Torudokimab is a humanized antibody expressed in CHO, targeting IL-33. Torudokimab has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145.22 kDa. The isotype control for Torudokimab can refer to Human IgG4 kappa, Isotype Control (HY-P99003).
loading...
    loading...
Art. -Nr.: HY-P99729
CAS. Nr.: 2222865-46-3
Synonyms: GSK 3772847; CNTO-7160

Target:  

Interleukin Related

Forschungsgebiete:  

Inflammation/Immunology

Melrilimab (GSK 3772847; CNTO-7160) is a humanized IgG2σ monoclonal antibody that targets the IL-33 receptor ST2 and blocks the IL-33/ST2 signaling pathway by binding to the ST2 protein. Melrilimab is applicable to research related to asthma and atopic dermatitis .
loading...
    loading...
Art. -Nr.: HY-126195
CAS. Nr.: 531-46-4
Reinheit:  99.41%
Synonyms: ML-090
Target:  

NADPH Oxidase

Forschungsgebiete:  

Neurological Disease

Fluoflavine (ML-090) is a selective NOX1 inhibitor and reactive oxygen species inhibitor. Fluoflavine reduces reactive oxygen species production, NOX1-mediated downstream signaling events, and oxygen-glucose deprivation-induced retinal ganglion cell death. Fluoflavine inhibits NADPH oxidase activity and pathological retinal neovascularization induced by oxygen-induced retinopathy in the retinas of ischemic mice. Fluoflavine can be used in studies related to retinal ischemia-reperfusion injury and proliferative retinopathy .
loading...
    loading...
Art. -Nr.: HY-P991150
CAS. Nr.: 2981477-39-6

Target:  

Interleukin Related

Forschungsgebiete:  

Inflammation/Immunology

Ompekimig is an immunoglobulin monoclonal antibody that targets IL-4, IL-13, IL-33. Ompekimig shows potential for use in immune-mediated inflammatory diseases such as asthma and atopic dermatitis .
loading...
    loading...
Art. -Nr.: HY-174607
Target:  

mRNA

Forschungsgebiete:  

Inflammation/Immunology

Human IL33 mRNA encodes the human interleukin 33 (IL33) protein, a cytokine that binds to the IL1RL1/ST2 receptor. IL33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells.
loading...
    loading...
Art. -Nr.: HY-RS06757
Forschungsgebiete:  

Others

IL33 Human Pre-designed siRNA Set A contains three designed siRNAs for IL33 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Art. -Nr.: HY-RS23101
Forschungsgebiete:  

Others

Il33 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il33 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...