78 Results for "

Insulin-like growth factor 1

" in MedChemExpress (MCE) Product Catalog:
Products (78)

78 Results for "Insulin-like growth factor 1" in MCE Product Catalog:

31
31 Publications Verification
Cat. No.: HY-15494
CAS No.: 477-47-4
Purity:  99.85%
Synonyms: AXL1717; Picropodophyllotoxin; PPP
Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
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27
27 Cited Publications
Cat. No.: HY-P7018
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin like growth factor 1; IGF1A; IGF-I; MGF; Insulin-like growth factor 1; Insulin-like growth factor IB; Insulin-like growth factor I; Insulin-like growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-like
Species:  
Human
Source:  
E. coli
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14
14 Cited Publications
Cat. No.: HY-50866
CAS No.: 475489-16-8
Synonyms: AEW541
Research Areas:  

Endocrinology Cancer

NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 has antitumor activity .
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12
12 Cited Publications
Cat. No.: HY-P7070
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin like growth factor 1; IGF1A; IGF-I; MGF; Insulin-like growth factor 1; Insulin-like growth factor IB; Insulin-like growth factor I; Insulin-like growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-like
Species:  
Mouse
Source:  
E. coli
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11
11 Cited Publications
Cat. No.: HY-14734
CAS No.: 249921-19-5
Purity:  99.94%
Synonyms: RC-1291; ONO-7643
Target:  

GHSR

Research Areas:  

Endocrinology Cancer

Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia .
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11
11 Cited Publications
Cat. No.: HY-14734A
CAS No.: 861998-00-7
Purity:  99.59%
Synonyms: RC-1291 hydrochloride; ONO-7643 hydrochloride
Target:  

GHSR

Research Areas:  

Endocrinology Cancer

Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia .
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7
7 Cited Publications
Cat. No.: HY-10524
CAS No.: 1089283-49-7
Purity:  99.03%
Research Areas:  

Endocrinology Cancer

GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity .
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6
6 Cited Publications
Cat. No.: HY-P70788
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin like growth factor 1; IGF1A; IGF-I; MGF; Insulin-like growth factor 1; Insulin-like growth factor IB; Insulin-like growth factor I; Insulin-like growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-like
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-P70698
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin like growth factor 1; IGF1A; IGF-I; MGF; Insulin-like growth factor 1; Insulin-like growth factor IB; Insulin-like growth factor I; Insulin-like growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-like
Species:  
Mouse
Source:  
E. coli
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3
3 Cited Publications
Cat. No.: HY-P7203
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin like growth factor 1; IGF1A; IGF-I; MGF; Insulin-like growth factor 1; Insulin-like growth factor IB; Insulin-like growth factor I; Insulin-like growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-like
Species:  
Rat
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-B0025
CAS No.: 83480-29-9
Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis .
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2
2 Cited Publications
Cat. No.: HY-P70783
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin like growth factor 1; IGF1A; IGF-I; MGF; Insulin-like growth factor 1; Insulin-like growth factor IB; Insulin-like growth factor I; Insulin-like growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-like
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P78723
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I Receptor; Insulin like growth factor 1 Receptor; MGC18216; Insulin-like growth factor 1 Receptor; Insulin-like growth factor I Receptor; JTK13; Receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase Receptor; IGFIR; CD221 Antigen; IGFR; IGF1R Protein
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-135680
CAS No.: 1094048-77-7
Purity:  98.03%
Synonyms: I-OMe-AG 538
Target:  

IGF-1R

Research Areas:  

Metabolic Disease Cancer

I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells.?I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC50?of 1 μM .
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1
1 Cited Publications
Cat. No.: HY-P700093AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin like growth factor 1; IGF1A; IGF-I; MGF; Insulin-like growth factor 1; Insulin-like growth factor IB; Insulin-like growth factor I; Insulin-like growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-like
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P700478
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin like growth factor 1; IGF1A; IGF-I; MGF; Insulin-like growth factor 1; Insulin-like growth factor IB; Insulin-like growth factor I; Insulin-like growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-like
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-P99197
CAS No.: 943453-46-1
Synonyms: CP-751871

Target:  

IGF-1R

Research Areas:  

Cancer

Figitumumab (CP-751871) is a potent and fully human monoclonal anti–insulin-like growth factor 1 receptor (IGF1R) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC50 of 1.8 nM .
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Cat. No.: HY-18785
CAS No.: 854171-35-0
Target:  

IGF-1R

Research Areas:  

Endocrinology Cancer

Indirubin Derivative E804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R.
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Cat. No.: HY-145110
CAS No.: 1116236-15-7
Purity:  98.36%
Target:  

IGF-1R

Research Areas:  

Cancer

IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis .
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Cat. No.: HY-15494R
CAS No.: 477-47-4
Synonyms: AXL1717 (Standard); Picropodophyllotoxin (Standard); PPP (Standard)
Picropodophyllin (Standard) is the analytical standard of Picropodophyllin. This product is intended for research and analytical applications. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
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