7 Results for "

MMF

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "MMF" in MCE Product Catalog:

13
Mycophenolate Mofetil
Mycophenolate Mofetil
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13 Publications Verification
Cat. No.: HY-B0199
CAS No.: 128794-94-5
Synonyms: RS 61443; TM-MMF
Category:  

Monophenols Phenols Endogenous metabolite Disease Research Fields Cancer

Target:  

Drug Metabolite Apoptosis Endogenous Metabolite Bacterial

Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation .
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13
Mycophenolate mofetil hydrochloride
Mycophenolate mofetil hydrochloride
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13 Publications Verification
Cat. No.: HY-B0199A
CAS No.: 116680-01-4
Synonyms: RS 61443 hydrochloride; TM-MMF hydrochloride
Category:  

Monophenols Phenols Endogenous metabolite Disease Research Fields Cancer

Target:  

Interleukin Related

Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection) .
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5
Diroximel fumarate
Diroximel fumarate
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5 Cited Publications
Cat. No.: HY-100375
CAS No.: 1577222-14-0
Purity:  99.90%
Synonyms: ALKS 8700; BIIB098
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity .
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1
Mycophenolate Mofetil-d4
Mycophenolate Mofetil-d4
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1 Cited Publications
Cat. No.: HY-B0199S
CAS No.: 1132748-21-0
Mycophenolate Mofetil-d4 is the deuterium labeled Mycophenolate Mofetil. Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection) .
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Mycophenolate Mofetil (Standard)
Mycophenolate Mofetil (Standard)
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Cat. No.: HY-B0199R
CAS No.: 128794-94-5
Synonyms: RS 61443 (Standard); TM-MMF (Standard)
Category:  

Monophenols Phenols Endogenous metabolite

Target:  

Reference Standards Interleukin Related

Mycophenolate Mofetil (Standard) is the analytical standard of Mycophenolate Mofetil. This product is intended for research and analytical applications. Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection) .
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Mycophenolate Mofetil-d4 hydrochloride
Mycophenolate Mofetil-d4 hydrochloride
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Cat. No.: HY-B0199AS
Synonyms: RS 61443-d4 hydrochloride; TM-MMF-d4 hydrochloride
Mycophenolate Mofetil-d4 hydrochloride is deuterated labeled Mycophenolate mofetil hydrochloride (HY-B0199A). Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection) .
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Diroximel fumarate (Standard)
Diroximel fumarate (Standard)
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Cat. No.: HY-100375R
CAS No.: 1577222-14-0
Synonyms: ALKS 8700 (Standard); BIIB098 (Standard)
Target:  

Reference Standards Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

Diroximel fumarate (Standard) is the analytical standard of Diroximel fumarate (HY-100375). This product is intended for research and analytical applications. Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity .
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