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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
119 Results for "
Major compounds
" in MedChemExpress (MCE) Product Catalog:
Products (119)
119 Results for "Major compounds" in MCE Product Catalog:
36
36 Publications Verification
Synonyms: 3-O-Caffeoylquinic acid; Heriguard; NSC-407296
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Tecovirimat (ST-246) is an orally bioavailable and selective compound against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus .
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3 Cited Publications
Synonyms: ST-246 monohydrate
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Tecovirimat (ST-246) monohydrate is the monohydrate form of Tecovirimat (HY-14805). Tecovirimat monohydrate is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat monohydrate is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat monohydrate targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat monohydrate exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat monohydrate could be used in the study for orthopoxvirus-induced diseases .
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1 Cited Publications
Synonyms: Frambione; 4-(4-Hydroxyphenyl)-2-butanone
Category:
Cardiovascular Disease Monophenols Rubus idaeus Linn. Rosaceae Phenols Plants Disease Research Fields
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Synonyms: 3-Phenylpropionic acid; 3-Phenylpropanoic acid; 3-Phenyl-n-propionic acid
Cat. No.: HY-W016388
CAS No.: 1689-64-1
Synonyms: 9-Hydroxyfluorene
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9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 µM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo .
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Ketones, Aldehydes, Acids Plants Curcuma longa Disease Research Fields Inflammation/Immunology Zingiberaceae
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Cat. No.: HY-W015788
CAS No.: 93-56-1
Synonyms: Styrene Glycol
Cat. No.: HY-124481
CAS No.: 289030-99-5
Synonyms: PTA
Category:
Leguminosae Caesalpinia sappan L. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
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Synonyms: Isorhamnetin-3,7-diglucoside; Isorhamnetin diglucoside
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Flavonols Flavonoids Brassica oleracea L. Metabolic Disease Phenols Polyphenols Plants Brassicaceae Disease Research Fields
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Cat. No.: HY-W012956
CAS No.: 1072-83-9
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6-Hydroxybenzbromarone is the major metabolite of Benzbromarone with a longer half-life and greater pharmacological potency than the parent compound. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor with an IC50 value of 21.5 μM. 6-Hydroxybenzbromarone is an anti-angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting .
Cat. No.: HY-N0357
CAS No.: 873001-54-8
Category:
Triterpenes Terpenoids Other Diseases Cucurbitaceae Trichosanthes kirilowii Maxim. Plants Disease Research Fields
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Synonyms: 3-O-Caffeoylquinic acid (Standard); Heriguard (Standard); NSC-407296 (Standard)
Cat. No.: HY-N8796
CAS No.: 75679-58-2
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2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone is a dihydrochalcone compound isolated from Iryanthera juruensis Warb. 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone is a major cytotoxic metabolite when tested against a panel of cancer cell lines .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
