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Native Proteins

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448

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5

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436

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4

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2

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3

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1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W250978
    Ovalbumins
    4 Publications Verification

    Endogenous Metabolite Cardiovascular Disease Infection Inflammation/Immunology Cancer
    Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .
    We recommend using Ovalbumin, low endotoxin (HY-W250978A) to establish an asthma model.
    Ovalbumins
  • HY-15435
    CHAPS
    4 Publications Verification

    Exosomes Biochemical Assay Reagents Others
    CHAPS is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm-Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS is commonly used in research on the separation and purification of membrane proteins .
    CHAPS
  • HY-P3152
    Streptavidin
    5 Publications Verification

    Biochemical Assay Reagents Others
    Streptavidin is a ~60 kDa homotetramer. Streptavidin binds four molecules of biotin with the highest affinity. The binding affinity of biotin to streptavidin is one of the highest reported for a non-covalent interaction to date, with a KD ~0.01 pM . Streptavidin has an immunosuppressive role .
    This product is a Streptavidin protein recombinantly expressed in an E. coli expression system.
    Streptavidin
  • HY-P99930
    Efruxifermin
    2 Publications Verification

    AKR-001; AMG-876

    FGFR Metabolic Disease
    Efruxifermin is an Fc-FGF21 fusion protein (human IgG1 Fc domain linked to a modified human FGF21). Efruxifermin has prolonged half-life and enhanced receptor affinity compared with native human FGF21. Efruxifermin can be used for the research of non-alcoholic steatohepatitis .
    Efruxifermin
  • HY-112641A
    AkaLumine hydrochloride
    5 Publications Verification

    Fluorescent Dye Cancer
    AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets .
    AkaLumine hydrochloride
  • HY-P3160
    Fibronectin
    5+ Cited Publications

    Integrin Cardiovascular Disease Inflammation/Immunology
    Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans .
    This product is a human Fibronectin obtained by recombinant expression in a rice expression system.
    Fibronectin
  • HY-NP010

    MMP Others
    Collagen, rat tail is a kind of collagen extracted from rat tail tendon tissue. Collagen, rat tail stimulates cell growth. Collagen, rat tail is often used as an attachment substrate for cell culture .
    Type I Collagen, from rat tail
  • HY-P2352
    Fetuin, Fetal Bovine Serum
    5 Publications Verification

    Biochemical Assay Reagents Metabolic Disease
    Fetuin, Fetal Bovine Serum is a liver-secreted 64 kDa plasma glycoprotein isolated from fetal bovine serum. Fetuin, Fetal Bovine Serum inhibits trypsin activity and promote cellular attachment, growth, and differentiation .
    Fetuin, Fetal Bovine Serum
  • HY-NP008

    Lipocalin Family Inflammation/Immunology
    β-Lactoglobulin, a major whey protein, is a small globular protein from the lipocalin family. β-Lactoglobulin is an important source of the essential and branched-chain amino acids (leucine, isoleucine, and valine). β-Lactoglobulin shows antioxidant properties, because it contains two disulfide bonds and one free thiol group. β-Lactoglobulin is a ligand transport agent. β-Lactoglobulin is one of the major allergens in milk and can be utilized in the research for developing safe hypoallergenic dairy products .
    β-Lactoglobulin
  • HY-P3161

    HSV Infection Inflammation/Immunology Cancer
    Lactoferrin from Bovine milk is a substance released by neutrophils. Lactoferrin from Bovine milk is an orally active multifunctional iron binding glycoprotein. Lactoferrin from Bovine milk prevents cell adhesion, growth and spreading of cell colonies. Lactoferrin from Bovine milk also has antiviral activity and inhibits microbial and viral adhesion and entry into host cells. Besides, Lactoferrin from Bovine milk has anti-inflammatory, immunomodulatory, and anti-cancer activities .
    Lactoferrin from Bovine milk
  • HY-P3160C

    Biochemical Assay Reagents Infection
    Fibronectin, bovine plasma is a fibronectin derived from bovine plasma. Fibronectin is an extracellular matrix protein that is upregulated and essential in many developmental processes, and also exists in the pathological progression of tissues and wound healing. Fibronectin specifically binds to a large number of molecules, including other components of the extracellular matrix, signaling molecules and cell adhesion molecules. The interaction between cells and fibronectin leads to bidirectional crosstalk, which regulates cell functions and induces cell-dependent changes in the extracellular matrix. Fibronectin, bovine plasma inhibits the production of bovine leukemia virus (BLV) p24 core protein in naturally infected bovine peripheral blood mononuclear cells .
    Fibronectin, bovine plasma
  • HY-112096
    eCF506
    5+ Cited Publications

    NXP900

    Src Cancer
    eCF506 (NXP900) is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native “closed” conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer .
    eCF506
  • HY-P2232

    Ovotransferrin

    Bacterial Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    Conalbumin (Ovotransferrin) is an iron-binding protein present in egg white with antibacterial activity. Conalbumin can also be used to induce bronchial asthma. Conalbumin exhibits induced mRNA accumulation in chicken oviduct cells by estrogen and progesterone .
    Conalbumin
  • HY-NP002B

    Biochemical Assay Reagents Inflammation/Immunology
    Rabbit Serum Albumin is a plasma protein derived from rabbits. Rabbit Serum Albumin can hydrolyze the carbamate pesticide carbaryl and induce fever in rabbits. Rabbit Serum Albumin can be used for biochemical and immunological research, including vaccine developing .
    Rabbit Serum Albumin
  • HY-NP052

    OVA-Biotin

    Biochemical Assay Reagents Others
    Ovalbumin-Biotin is a biotinylated biochemical reagent. Ovalbumin-Biotin is used to label or detect specific antigens, molecules or cellular structures .
    Ovalbumin-Biotin
  • HY-N10264

    (+)-Avrainvillamide; CJ-17,665

    Antibiotic Infection Cancer
    Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .
    Avrainvillamide
  • HY-15435A
    CHAPS hydrate
    4 Publications Verification

    Biochemical Assay Reagents Exosomes Others
    CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .
    CHAPS hydrate
  • HY-NP164

    Con A-HRP

    Fluorescent Dye Cancer
    Concanavalin A-HRP (Con A-HRP) is a HRP-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .


    Concanavalin A-HRP
  • HY-P3267A

    Ferroportin Transferrin Receptor Neurological Disease
    Apo-Bovine Transferrin refers to iron free Transferrin (HY-P3267), serves as Transferrin receptor ligand and mediates iron release from endothelial cells. Apo-Transferrin can directly bind to hephaestin, which can convert Fe 2+ to Fe 3+. Apo-Transferrin mediates iron efflux most likely in cooperation with ferroportin 1. Apo-Bovine Transferrin can be used in neuroretinal research .
    Apo-Bovine Transferrin
  • HY-P3394

    CTB, from vibrio cholerae

    Biochemical Assay Reagents Others
    Cholera toxin B subunit, from vibrio cholerae (CTB, from vibrio cholerae) is non-toxic to cells and possesses no intrinsic adenylate cyclase activity. Cholera toxin B subunit, from vibrio cholerae attaches to cells by binding to ganglioside GM1.8 CTB has been shown to be a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface), but not for oligodendrocytes or astrocytes. Cholera toxin B subunit, from vibrio cholerae has been reported to be an excellent tracer for the study of axonal transport using immunohistochemical methods. Cholera toxin B subunit, from vibrio cholerae has been widely used as a marker of membrane lipid rafts .
    Cholera toxin B subunit, from vibrio cholerae
  • HY-NP009

    Bacterial Infection Neurological Disease
    α-Lactalbumin is a globular whey protein that exists in milk. α-Lactalbumin binds Ca 2+, Mg 2+, Mn 2+, Na +, K + and Zn 2+ ions; among these, Ca 2+ binding enhances protein stability, while Zn 2+ binding reduces stability and induces aggregation. α-Lactalbumin forms amyloid fibrils, amorphous aggregates, nanoparticles and nanotubes depending on external conditions. α-Lactalbumin exhibits bactericidal and antiviral activities. α-Lactalbumin has anxiolytic and antidepressant activities, and its effects are enhanced under stress conditions .
    α-Lactalbumin
  • HY-NP001
    Cationic Bovine Serum Albumin
    1 Publications Verification

    CBSA

    Biochemical Assay Reagents Neurological Disease
    Cationic Bovine Serum Albumin is a bovine serum albumin (BSA) modified with excess ethylenediamine, which has enhanced immunogenicity compared to native BSA. Positively charged primary amines block all negatively charged carboxyl groups, making Cationic Bovine Serum Albumin a cationic protein. Cationic Bovine Serum Albumin has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .
    Cationic Bovine Serum Albumin
  • HY-125864B

    MMP Cadherin Cardiovascular Disease Neurological Disease
    Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction .
    Murine Fibrinogen
  • HY-W998680

    5-FITC-Maleimide

    Fluorescent Dye Others
    Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .
    Fluorescein-maleimide
  • HY-P2975

    Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)

    Endogenous Metabolite Biochemical Assay Reagents Neurological Disease
    Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.
    Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)
  • HY-NP0184

    PHA-L (Biotinylated)

    Fluorescent Dye Others
    Phaseolus Vulgaris Leucoagglutinin (PHA-L) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Phaseolus Vulgaris Leucoagglutinin (PHA-L) Biotinylated is a biological material or organic compound that can be used in life science research .
    Phaseolus Vulgaris Leucoagglutinin (Biotinylated)
  • HY-P3443
    Peanut agglutinin
    1 Publications Verification

    PNA

    Biochemical Assay Reagents Cancer
    Peanut agglutinin (PNA) is a carbohydrate-recognition protein that binds competitively and irreversibly to cell-surface β-D-Gal (1-3)-GalNAc, and this binding can be inhibited by D-galactose and asialofetuin. Peanut agglutinin recognizes exposed glycoepitopes and reflects the glycosylation status of cells. Peanut agglutinin can label glycoconjugates at neuromuscular junctions to safely visualize synaptic structures. Peanut agglutinin can be used to synthesize dyes to distinguish between normal and tumor tissues. Peanut agglutinin provides support for research on leukemia, Burkitt's tumors, and cutaneous squamous lesions .
    Peanut agglutinin
  • HY-NP0196

    Mouse IgG

    Biochemical Assay Reagents Inflammation/Immunology
    Mouse Immunoglobulin G (Mouse IgG) is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .
    Mouse immunoglobulin G
  • HY-NP143

    Biochemical Assay Reagents Neurological Disease
    Nerve Growth Factor 2.5S, murine submaxillary gland is a neurotrophic polypeptide required for normal growth and development of sympathetic and embryonic sensory neurons and certain cholinergic neurons in the central nervous system. Nerve Growth Factor 2.5S, murine submaxillary gland has only β-subunit , and shows nerve growth-promoting activity .
    Nerve Growth Factor 2.5S,murine submaxillary gland
  • HY-42984

    Biochemical Assay Reagents Others
    BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. UBHQ-2 NHS has a wide and intense quenching range from 560-670 nm, which makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    BHQ-2 NHS
  • HY-NP041

    BSA-PE

    Biochemical Assay Reagents Others
    Bovine Serum Albumin-PE (BSA-PE) is a biochemical reagent conjugated to fluorescein PE (Ex=565 nm; Em=578 nm). Bovine Serum Albumin-PE can be used to label or detect specific antigens, molecules or cellular structures .
    Bovine Serum Albumin-PE
  • HY-NP0190

    UEA I (Biotinylated)

    Fluorescent Dye Others
    Ulex Europaeus Agglutinin I Biotinylated (UEA I Biotinylated) is a biotinylated lectin that binds to α1,2-fucosylated proteins and cell-surface glycoconjugates containing α-L-fucose. Ulex Europaeus Agglutinin I Biotinylated serves as a histochemical marker for endothelial cells .
    Ulex Europaeus Agglutinin I (Biotinylated)
  • HY-NP0181

    MAL II (Biotinylated)

    Fluorescent Dye Others
    Maackia Amurensis Lectin II (MAL II) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin II (MAL II) Biotinylated is a biological material or organic compound that can be used in life science research .
    Maackia Amurensis Lectin II (Biotinylated)
  • HY-W355779

    Tyrosylprolylglutaminylprolylglutamine

    Biochemical Assay Reagents Inflammation/Immunology
    Gliadins (Tyrosylprolylglutaminylprolylglutamine) comprise a family of glutamine- and proline-rich monomeric proteins that plays an role in autoimmune disease, such as celiac disease .
    Gliadins
  • HY-NP113

    Chick Type II collagen, immunization grade

    MMP Inflammation/Immunology
    Highly purified Type II collagen, from chick sternal cartilage (Chick Type II collagen, immunization grade) is an immune grade collagen derived from chick sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type II collagen, from chick sternal cartilage
  • HY-NP0180

    LCA (Biotinylated)

    Fluorescent Dye Others
    Lens Culinaris Agglutinin (LCA) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Lens Culinaris Agglutinin (LCA) Biotinylated is a biological material or organic compound that can be used in life science research .
    Lens Culinaris Agglutinin (Biotinylated)
  • HY-NP068

    GSL I

    Fluorescent Dye Others
    Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a biological material or organic compound that can be used in life science research .
    Griffonia (Bandeiraea) Simplicifolia Lectin I
  • HY-NP079

    RCA I

    Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I
  • HY-NP002A

    Biochemical Assay Reagents Others
    Goat Serum Albumin is a plasma protein derived from goats. Goat Serum Albumin is a versatile protein commonly used in various life sciences research applications, including immunoassays and the production and purification of monoclonal antibodies .
    Goat Serum Albumin
  • HY-E70565

    Endonuclease Inflammation/Immunology
    O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-type O-glycosylated proteins. O-Glycoprotease sequence is from Akkermansia muciniphila, recombinantly expressed in E.coli, with a 6×His tag at the C-terminus.
    The enzyme maintains high activity between pH 5.5-7.5 and is resistant to 1M NaCl, but is highly sensitive to EDTA (0.5 mM EDTA) and can be inhibited by Zn 2+.
    O-Glycoprotease
  • HY-W1005067

    Molecular Glues Hippo (MST) Estrogen Receptor/ERR Others
    EN171 is a covalent ligand that covalently targets both C38 and C96 on 14-3-3 to enhance 14-3-3 interactions with ERα, YAP and TAZ, leading to impaired estrogen receptor and Hippo pathway transcriptional activity. EN171 can not only be used as a molecular glue to enhance native protein interactions but can also be used as a covalent 14-3-3 recruiter in heterobifunctional molecules to sequester nuclear neo-substrates such as BRD4 and BLC6 into the cytosol .
    EN171
  • HY-149552

    OGT Cancer
    Ac4-5SGlcNAc is an O-GlcNAc transferase (OGT) inhibitor. Ac4-5SGlcNAc converts intracellularly to UDP-5SGlcNAc, which competes with native UDP-GlcNAc (HY-148596) to block OGT catalytic activity, reduces cellular UDP-GlcNAc pools, and limits global protein O-GlcNAcylation. Ac4-5SGlcNAc reduces OGA levels via feedback, alters lectin signal intensities and glycan-related band masses. Ac4-5SGlcNAc can be used for the research of breast cancer .
    Ac4-5SGlcNAc
  • HY-NP055
    Ovalbumin-Cy5
    1 Publications Verification

    OVA-Cy5

    Fluorescent Dye Cancer
    Ovalbumin-Cy5 is Cy5-labeled Ovalbumin (OVA) .
    Ovalbumin-Cy5
  • HY-NP126

    Porcine Type XI collagen, immunization grade

    MMP Inflammation/Immunology
    Highly purified Type XI collagen, from porcine articular cartilage (Porcine Type XI collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
    Highly purified Type XI collagen, from porcine articular cartilage
  • HY-NP0195

    Sheep IgG

    Inflammation/Immunology
    Sheep Immunoglobulin G (Sheep IgG) is a sheep serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA .
    Sheep immunoglobulin G
  • HY-NP158A

    Biochemical Assay Reagents Others
    Type II Collagen, T Cell Grade, from Chick is a T-cell dependent antigen with unique immunological features. Type II Collagen, T Cell Chick, from Bovine can be used as a stimulating antigen for T-cells in in vitro culture systems .
    Type II Collagen, T Cell Grade, from Chick
  • HY-NP164B

    Con A-AF488

    Fluorescent Dye Cancer
    Concanavalin A-AF488 (Con A-AF488) is an AF488-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF488
  • HY-NP072

    MAL I

    Fluorescent Dye Others
    Maackia Amurensis Lectin I (MAL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) is a biological material or organic compound that can be used in life science research .
    Maackia Amurensis Lectin I
  • HY-D0167

    Fluorescent Dye Others
    NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
    NHS-5(6)Carboxyrhodamine
  • HY-W615327

    Biochemical Assay Reagents Others
    Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact.
    Bis-sulfone NHS ester

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