2. Search Result
Search Result
Results for "

Near-infrared fluorescence imaging

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

23

Fluorescent Dyes

3

Peptides

2

Inhibitory Antibodies

1

Natural
Products

2

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1540
    Cyanine5.5 amine
    1 Publications Verification

    Cy 5.5 amine; Lumiprobe Cy 5.5 amine

    		 Fluorescent Dye Others
    Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
    Cyanine5.5 amine
  • HY-145746
    Sulfo-Cy5 azide

    		Fluorescent Dye PD-1/PD-L1 Inflammation/Immunology Cancer
    Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
    Sulfo-Cy5 azide
  • HY-D1872
    800CW NHS ester

    		Fluorescent Dye Others
    800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .
    800CW NHS ester
  • HY-D1555
    Cyanine7 DBCO

    Cy7 DBCO

    		 Fluorescent Dye Others
    Cyanine7 DBCO (Cy7 DBCO) is a near-infrared fluorescent dye and an efficient bio-orthogonal quencher. Cyanine7 DBCO is formed by covalent connection of the near-infrared fluorescent dye Cy7 and the dibenzocyclooctyne (DBCO) functional group. After reacting with N3-Cy5-COOH, the fluorescence of Cy5 decreases by 90% within 90 minutes, and rapid signal attenuation can be observed within 2-5 minutes. Cyanine7 DBCO can be used for the study of deep tissue imaging and receptor-targeted therapeutic strategies .
    Cyanine7 DBCO
  • HY-P6083
    RTSPSSR

    		Biochemical Assay Reagents Others Cancer
    RTSPSSR is synthesized peptide, which binds specifically to claudin-1 and visulizes the CRC tumor in mice, through near-infrared fluorescence imaging .
    RTSPSSR
  • HY-D2062
    ATTO 740 NHS ester

    		Fluorescent Dye Integrin Cancer
    ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
    ATTO 740 NHS ester
  • HY-D1450
    IR-1048

    S01448

    		 Fluorescent Dye Cancer
    IR-1048 is a nitroreductase (NTR)-responsive near-infrared fluorescence (NIR)/photoacoustic (PA) imaging probe and photothermal agent. IR-1048 is coupled with a nitroimidazole group to form IR-1048-MZ. IR-1048-MZ is catalytically reduced by NTR in a hypoxic environment, restoring strong near-infrared absorption and fluorescence emission (NIR II window), while activating the photothermal effect. IR-1048 relies on NTR-mediated electron transfer to relieve intramolecular fluorescence quenching, achieving specific imaging and photothermal ablation of tumor hypoxic areas. IR-1048 is mainly used for high-contrast NIR II/photoacoustic imaging and photothermal therapy research and tumor diagnosis of the tumor hypoxic microenvironment .
    IR-1048
  • HY-D2971
    NCIC-VIS

    		Fluorescent Dye Autophagy Neurological Disease
    NCIC-VIS is a lysosome-targeted, viscosity-sensitive two-photon near-infrared fluorescent probe. NCIC-VIS has a rigid structure that can restrict molecular torsion, thereby increasing the fluorescence quantum yield and two-photon absorption cross-section. NCIC-VIS enables real-time imaging of the autophagy process in cells .
    NCIC-VIS
  • HY-D1391
    PbS/CdS QDs

    PbS/CdSe QD

    		 Fluorescent Dye Others
    PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window .
    PbS/CdS QDs
  • HY-P991650
    MDX1201

    		PSMA Cancer
    MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .
    MDX1201
  • HY-D2060
    ATTO 740

    		Fluorescent Dye Others
    ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
    ATTO 740
  • HY-165424
    NIR-BG2

    		Fluorescent Dye Glycosidase Cardiovascular Disease Cancer
    NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated β-galactosidase (SA-β-Gal). NIR-BG2 is activated by SA-β-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence .
    NIR-BG2
  • HY-D3000
    NIR-RED ROS-H2O2 Probe

    		Fluorescent Dye Metabolic Disease
    NIR-RED ROS-H2O2 Probe is a near-infrared fluorescent probe used for detecting hydrogen peroxide (H₂O₂) and featuring dual-modal fluorescence/photoacoustic imaging capabilities. NIR-RED ROS-H2O2 Probe successfully detects the upregulated fluorescence signal of H₂O₂ in HepG2 cells and a mouse liver injury model. NIR-RED ROS-H2O2 Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
    NIR-RED ROS-H2O2 Probe
  • HY-D1065
    NIR-H2O2

    		Fluorescent Dye Inflammation/Immunology
    NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
    NIR-H2O2
  • HY-P5520
    GB-6

    		Bombesin Receptor Radionuclide-Drug Conjugates (RDCs) Cancer
    GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
    GB-6
  • HY-152102
    BTCy

    		Fluorescent Dye Cancer
    BTCy is a near-infrared (NIR) fluorescence probe with polarity-responsive and cell plasma membrane-targeting properties. BTCy can be used for in vivo imaging of tumor tissue (λex = 561 nm, λem = 600-700 nm) .
    BTCy
  • HY-D2940
    SiR-SNAP

    SiR650-BG

    		 Fluorescent Dye Others
    SiR-SNAP (SiR650-BG) is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .
    SiR-SNAP
  • HY-D3214
    NIR-Cu(Ⅱ)

    		Fluorescent Dye Others
    NIR-Cu (Ⅱ) is a near-infrared fluorescent Cu 2+ probe. NIR-Cu (Ⅱ) enables fluorescence imaging of Cu 2+ in living mice. NIR-Cu (Ⅱ) reduces self-absorption and exhibits minimal photobleaching, thus supporting in vivo imaging applications .
    NIR-Cu(Ⅱ)
  • HY-D2279
    NFL-NH2

    		Fluorescent Dye Inflammation/Immunology
    NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .
    NFL-NH2
  • HY-D2194
    AgAuSe-COOH (1000 nm)

    		Fluorescent Dye Others
    AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
    AgAuSe-COOH (1000 nm)
  • HY-P10788
    CK3 peptide

    		Complement System Cancer
    CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.
    CK3 peptide
  • HY-D2970
    Golgi-P

    		Fluorescent Dye Neurological Disease
    Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm). Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression .
    Golgi-P
  • HY-D3234
    Cy-AP

    		Fluorescent Dye Others
    Cy-AP is a hypoxia-sensitive near-infrared Fluorescent probe (emission wavelength: 725 nm). Cy-AP exhibits no fluorescence under normoxic microenvironments, while under hypoxic microenvironments, its azo group is reduced, releasing strong near-infrared fluorescence with an emission at 725 nm. Cy-AP enables visualization of intracellular hypoxic status through multiple imaging modalities .
    Cy-AP
  • HY-149835
    TTX-P

    		Fluorescent Dye Others
    TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .
    TTX-P
  • HY-D2968
    DCM–ONOO

    		Fluorescent Dye Neurological Disease
    DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO⁻) in epilepsy models. DCM-ONOO exhibits excellent optical properties, with a single photon excitation (Ex) of 520 nm; a single photon emission (Em) of 685 nm; a two-photon excitation of 820 nm; and a Stokes shift of 165 nm. When DCM-ONOO is combined with ONOO⁻, it shifts from 460 nm to 512 nm, and only generates a significant fluorescence response to ONOO⁻. DCM-ONOO has been successfully applied to rat epilepsy models .
    DCM–ONOO
  • HY-D2998
    ONOO-LysopH

    		Fluorescent Dye Others
    ONOO-LysopH is a new Rhodamine-based near-infrared fluorescent probe. ONOO-LysopH is acid-sensitive, exhibiting rapid near-infrared fluorescence enhancement around 686 nm under acidic pH conditions. ONOO-LysopH also displays a rapid NIR turn-on fluorescence around 678 nm for ONOO− at physiological pH. ONOO-LysopH can target lysosomes to track lysosomal pH changes and image endogenous/exogenous ONOO− in live cells. ONOO-LysopH is applicable for cell imaging ONOO− and tracking lysosomal pH changes .
    ONOO-LysopH
  • HY-D3222
    NIR-PN1

    		Fluorescent Dye Neurological Disease
    NIR-PN1 is a blood-brain barrier-permeable near-infrared fluorescent indicator targeting peroxynitrite anion (ONOO −) (Ex/Em = 510 nm/670 nm). NIR-PN1 reacts with ONOO − to trigger a strong near-infrared fluorescence enhancement, enabling the detection of ONOO − flux. NIR-PN1 allows the imaging of ONOO − flux in various Parkinson's disease models. NIR-PN1 is applicable to Parkinson's disease-related research .
    NIR-PN1
  • HY-P992459
    SGM-101 Antibody

    		ADC Antibody Transmembrane Glycoprotein Cancer
    SGM-101 Antibody is a chimeric monoclonal antibody targeting carcinoembryonic antigen (CEA). SGM-101 Antibody can serve as a tumor-specific fluorescent imaging probe after being covalently conjugated with the near-infrared fluorescent dye BM104 . SGM-101 Antibody accumulates in CEA-positive tumor tissues via antigen-antibody specific binding, and emits near-infrared fluorescence to enable imaging of tumor lesions. SGM-101 Antibody can be used in research related to gastric cancer, colorectal cancer, pancreatic cancer, non-small cell lung cancer, breast cancer, peritoneal carcinomatosis, and liver metastases .
    SGM-101 Antibody
  • HY-D3152
    NRh-Cu

    		Fluorescent Dye Others
    NRh-Cu is a highly sensitive near-infrared fluorescence turn-on indicator and Cu 2+-selective probe (λex=680 nm, λem=740 nm). When NRh-Cu interacts with Cu 2+, it undergoes a structural transition from a non-fluorescent spirocyclic state to a fluorescent ring-opened state, which drives the enhancement of fluorescence emission. NRh-Cu can be used for Cu 2+ imaging in live cells and in vivo .
    NRh-Cu
  • HY-D2962
    CAQ

    		Fluorescent Dye Neurological Disease
    CAQ is a near-infrared fluorescent probe based on a curcumin scaffold (Ex/Em = 565/635). CAQ exhibits high affinity for Aβ1-42 aggregates (Kd = 78.89 nM) and excellent selectivity toward common biomolecules. CAQ’s emission wavelength shows significant solvent dependence. CAQ, by incorporating intramolecular rotation donors and quinoline functional groups, can be used for the specific detection and imaging of Aβ aggregates in Alzheimer's disease .
    CAQ
  • HY-D3235
    FDOCl-22

    		Fluorescent Dye Endocrinology
    FDOCl-22 is a HOCl-responsive probe. FDOCl-22 reacts with hypochlorous acid to significantly enhance near-infrared emission and absorption signals, enabling the detection of HOCl levels associated with reagent-induced acute kidney injury. FDOCl-22 can be used in studies related to reagent-induced acute kidney injury .
    FDOCl-22

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: