17 Results for "

P388 lymphocytic leukemia

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "P388 lymphocytic leukemia" in MCE Product Catalog:

Cat. No.: HY-108603
CAS No.: 87745-28-6
Synonyms: (+)-Bryostatin 2
Target:  

PKC

Research Areas:  

Cancer

Bryostatin 2 ((+)-Bryostatin 2) is a 20-membered ring lactone that can be found in Bryozoan Eugufa neritina L. Bryostatin 2 has the potential for the research of P-388 lymphocytic leukemia .
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Cat. No.: HY-121123
CAS No.: 42381-05-5
Purity:  ≥97.0%
Synonyms: 2-Aminoadamantane-2-carboxylic acid
Target:  

Aminopeptidase

Research Areas:  

Cancer

Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5 .
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Cat. No.: HY-N1649
CAS No.: 678138-59-5
2,3,2'',3''-Tetrahydroochnaflavone is a biflavonoid, which can be isolated from the leaves of Quintinia acutifolia. 2,3,2'',3''-Tetrahydroochnaflavone shows some cytotoxicity against P388 murine lymphocytic leukemia cells, with an IC50 of 8.2 µg/mL .
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Cat. No.: HY-113578
CAS No.: 101708-64-9
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Cancer

PD 116152 is a phenazine Antibiotic with antimicrobial and antitumor activity. PD 116152 possesses cytotoxic activity against L1210 lymphocytic leukemia and human colon adenocarcinoma (HCT-8) cells with IC50 values of 5.2 x 10 -7 M and 7.1 x 10 -7 M, respectively. PD 116152 is promising for research of P388 lymphocytic leukemia .
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Cat. No.: HY-N18237
CAS No.: 101391-06-4
Bruceanol A is an antileukemic quassinoid glycoside isolated from Brucea javanica. Bruceanol A exhibits antileukemic activity against P-388 lymphocytic leukemia in vivo. Bruceanol A can be used in studies related to P-388 lymphocytic leukemia .
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Cat. No.: HY-N18086
CAS No.: 132587-61-2
Bruceanic acid D is a quassinoid compound and cytotoxic agent that can be isolated from the xylem powder of Brucea antidysenterica. Bruceanic acid D specifically inhibits P-388 lymphocytic leukemia cells but shows no activity against human lung cancer cells and human colon cancer cells. Bruceanic acid D can be used in studies related to P-388 lymphocytic leukemia .
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Cat. No.: HY-122997
CAS No.: 28937-85-1
Acetylaleuritolic acid is a triterpenoid isolated from Jatropha curcas that exhibits tumor suppressive properties against the P-388 lymphocytic leukemia test system.
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Cat. No.: HY-117476
CAS No.: 26790-94-3
Sapelin B is a naturally occurring tirucallane-type triterpenoid that exhibits in vivo antitumor activity in a mouse model of P-388 lymphocytic leukemia. Sapelin B can be used in leukemia-related research .
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Cat. No.: HY-N9210
CAS No.: 69251-99-6
1,2,3-Tri-O-methyl-7,8-methyleneflavellagic acid, a ellagic acid derivative of Agrostistachys hookeri, exhibits activity against cultured P-388 lymphocytic leukemia cells .
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Cat. No.: HY-187763
CAS No.: 88497-93-2
Target:  

Others

Research Areas:  

Cancer

Dircin is a daphnane-type diterpene ester natural product found in the branches and flowers of Dirca occidentalis A. Gray. It exhibits potent cytotoxicity against P-388 lymphocytic leukemia cells, with a ED50 of 0.00000025 μg/mL. Dircin can be used in studies of leukemia and plant-derived cytotoxic daphnane-type diterpene esters .
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Cat. No.: HY-N21674
CAS No.: 17413-41-1
Aristolactam I N-β-D-glucoside is a naturally occurring Aristolochic acid derivative. Aristolactam I N-β-D-glucoside exhibits cytotoxicity against mouse lymphocytic leukemia P-388 cells. Aristolactam I N-β-D-glucoside can be used in leukemia-related research .
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Cat. No.: HY-139090
CAS No.: 136587-07-0
Synonyms: 28-O-Acetyl-3-Oxobetulin; 3-oxo-28-O-Acetylbetulin
Research Areas:  

Cancer

3-Oxobetulin acetate (28-O-Acetyl-3-Oxobetulin; 3-oxo-28-O-Acetylbetulin) is a derivative of betulin (HY-N0083), a cholesterol biosynthesis inhibitor. 3-Oxobetulin acetate inhibits the growth of P388 murine lymphocytic leukemia cells (EC50=0.12 μg/mL) and human MCF-7 breast cancer, SF-268 CNS cancer, H460 lung cancer, and KM20L2 colon cancer cells (GI50s=8, 10.6, 5.2, and 12.7 μg/mL), but not BxPC-3 pancreatic cancer cells or DU145 prostate cancer cells (GI50s=>10 μg/mL for both). 3-Oxobetulin acetate inhibits the replication of X4-tropic recombinant HIV (NL4.3-Ren) in MT-2 lymphoblastoid cells (IC50=13.4 μM). 3-Oxobetulin acetate is also effective against Listeria donovani amastigotes.
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Cat. No.: HY-187153
CAS No.: 6003-11-8
Target:  

Topoisomerase

Research Areas:  

Metabolic Disease Cancer

Alizarin 2-methyl ether is a DNA topoisomerase inhibitor. Alizarin 2-methyl ether inhibits the relaxation of supercoiled DNA via DNA topoisomerase I and II. Alizarin 2-methyl ether promotes adipocyte differentiation by increasing lipid accumulation. Alizarin 2-methyl ether possesses antidiabetic and insulin-sensitizing properties. Alizarin 2-methyl ether can be used in research related to human colon cancer, P-388 lymphocytic leukemia and diabetes .
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Cat. No.: HY-N9784
CAS No.: 340997-02-6
2′′,3′′-Dihydroochnaflavone is a flavonoid/flavanone-type ether-linked biflavonoid anti-leukemic compound. 2′′,3′′-Dihydroochnaflavone exhibits significant cytotoxicity against P388 murine lymphocytic leukemia cells (IC50 = 3.1 μg/mL). It can be naturally extracted from the dried leaves of Quintinia acutifolia and has also been previously isolated and identified from Ochna interrima and Luxemburgia nobilis (both Ochnaceae plants). 2′′,3′′-Dihydroochnaflavone can be used in research related to anti-tumor (especially leukemia) applications .
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Cat. No.: HY-N18156
CAS No.: 66052-49-1
29β-Toosendanin is a toosendanin-type limonoid that is found in the root bark of Melia azedarach. 29β-Toosendanin exerts cytotoxic effects on lymphocytic leukemia cells in vitro. 29β-Toosendanin can be used for the research of leukemia .
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Cat. No.: HY-105136A
CAS No.: 41729-52-6
Target:  

Drug Derivative

Research Areas:  

Infection Cancer

Dezaguanine is a purine analog. Dezaguanine exhibits antitumor activity in leukemia and breast cancer cells. Dezaguanine can be used in cancer-related research .
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Cat. No.: HY-182259
CAS No.: 14410-23-2
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Montanastatin is an antitumor agent that can be isolated from the terrestrial actinomycete Streptomyces anulatus. Montanastatin inhibits the growth of various cancer cells. Montanastatin can be used in research related to lymphocytic leukemia, ovarian cancer, brain cancer, renal cancer, lung cancer, colon cancer and melanoma .
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