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Isoforms Recommended: PARP10
Results for "

PARP10

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

3

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148566
    OUL232
    2 Publications Verification

    		 PARP Cancer
    OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. OUL232 is the most potent PARP10 inhibitor described to date (IC50=7.8 nM), as well as the first PARP12 inhibitor ever reported .
    OUL232
  • HY-148753
    PARP10-IN-2

    		PARP Cancer
    PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC50s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively .
    PARP10-IN-2
  • HY-123512
    OUL35

    NSC39047

    		 PARP Cancer
    OUL35 (NSC39047) is a potent and selective inhibitor of ARTD10 (PARP-10), with an IC50 of 329 nM .
    OUL35
  • HY-148754
    PARP10-IN-3

    		PARP Cancer
    PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC50s of 1.7 μM for human PARP2 and human PARP15, respectively .
    PARP10-IN-3
  • HY-143398
    PARP10/15-IN-1

    		PARP Cancer
    PARP10/15-IN-1 (compound 8l) is a potent inhibitor of dual inhibitor of PARP10 and PARP15, with IC50s of 160 nM and 370 nM, respectively. PARP10/15-IN-1 can be used for cancer .
    PARP10/15-IN-1
  • HY-178317
    OUL312

    		PARP Apoptosis Infection Inflammation/Immunology Cancer
    OUL312 is a potent PARP10 inhibitor (IC50 = 20 nM), showing more than 75-fold greater selectivity for PARP15 (IC50 = 1500 nM). OUL312 is also at least 18-fold higher than all other human enzymes in the family. OUL312 has a good ADME profile, is able to enter cells, is not toxic, and effectively rescues human cells from PARP10-induced apoptosis at sub-micromolar concentrations. OUL312 can be used for the study of cervical cancer .
    OUL312
  • HY-146502
    PARP10/15-IN-3

    		PARP Apoptosis Cancer
    PARP10/15-IN-3 (Compound 8a) is a potent PARP10 and PARP15 dual inhibitor with IC50 values of 0.14 µM and 0.40 µM against PARP10 and PARP15, respectively. PARP10/15-IN-3 is able to enter cells and rescue cells from apoptosis .
    PARP10/15-IN-3
  • HY-146501
    PARP10/15-IN-2

    		PARP Apoptosis Cancer
    PARP10/15-IN-2 (Compound 8h) is a potent PARP10 and PARP15 dual inhibitor with IC50 values of 0.15 µM and 0.37 µM against PARP10 and PARP15, respectively. PARP10/15-IN-2 is able to enter cells and rescue cells from apoptosis .
    PARP10/15-IN-2
  • HY-RS10051
    Parp10 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) PARP Others

    Parp10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Parp10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Parp10 Mouse Pre-designed siRNA Set A
    Parp10 Mouse Pre-designed siRNA Set A
  • HY-148709
    ARTD10/PARP10-IN-1

    		PARP Inflammation/Immunology
    ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) with IC50s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively .
    ARTD10/PARP10-IN-1
  • HY-RS10050
    PARP10 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) PARP Others

    PARP10 Human Pre-designed siRNA Set A contains three designed siRNAs for PARP10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PARP10 Human Pre-designed siRNA Set A
    PARP10 Human Pre-designed siRNA Set A
  • HY-RS10052
    Parp10 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) PARP Others

    Parp10 Rat Pre-designed siRNA Set A contains three designed siRNAs for Parp10 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Parp10 Rat Pre-designed siRNA Set A
    Parp10 Rat Pre-designed siRNA Set A
  • HY-143338
    ART-IN-1

    		PARP Cancer
    ART-IN-1 (compound 7) is a selective PARP inhibitor with IC50s of 19, 22, 2.4, >100, 1.1 µM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively .
    ART-IN-1
  • HY-148710
    ARTD10/PARP10-IN-2

    		PARP Inflammation/Immunology
    ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively .
    ARTD10/PARP10-IN-2
  • HY-125217
    PARP10-IN-1

    		PARP Cancer
    PARP10-IN-1 is a PARP10 inhibitor with an IC50 of 1.8 μM, 2.7 μM, and >10-fold selectivity over most PARP family members, excluding PARP7 and PARP16.PARP10-IN-1 inhibits PARP10-mediated mono-ADP-ribosylation, including auto-MARylation of PARP10 and MARylation of its protein targets.PARP10-IN-1 is membrane permeable and inhibits PARP10-dependent MARylation in human embryonic kidney cells.PARP10-IN-1 can be used for the research of cancer .
    PARP10-IN-1
  • HY-180926
    PARP10-IN-4

    		PARP Cancer
    PARP10-IN-4 (compound 12Z) is a potent PARP10 inhibitor with a pIC50 of 7.95. also shows inhibitory activity against TNKS1, TNKS2, and PARP11 with pIC50 values of 6.95, 7.03, and 7.01, respectively .
    PARP10-IN-4

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