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Results for "

PNA sequence

" in MedChemExpress (MCE) Product Catalog:

22

Inhibitors & Agonists

2

Fluorescent Dyes

24

Peptides

Cat. No. Product Name Target Research Area
  • HY-P1103
    CTCE-9908
    1 Publications Verification

    		 CXCR Cancer
    CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
  • HY-106262B
    Delcasertib hydrochloride
    3 Publications Verification

    KAI-9803 hydrochloride; BMS-875944 hydrochloride

    		 PKC Cardiovascular Disease Inflammation/Immunology
    Delcasertib (KAI-9803) hydrochloride is a potent and selective δ-protein kinase C (δPKC) inhibitor. Delcasertib (KAI-9803) hydrochloride could ameliorate injury associated with ischemia and reperfusion in animal models of acute myocardial infarction (MI) .
  • HY-106262
    Delcasertib

    KAI-9803; BMS-875944

    		 PKC Cardiovascular Disease Inflammation/Immunology
    Delcasertib (KAI-9803) is a potent and selective δ-protein kinase C (δPKC) inhibitor. Delcasertib (KAI-9803) could ameliorate injury associated with ischemia and reperfusion in animal models of acute myocardial infarction (MI) .
  • HY-P3222
    Oxytocin antiparallel dimer

    		Peptides Endocrinology
    Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
  • HY-P3215
    Oxytocin parallel dimer

    		Oxytocin Receptor Endocrinology
    Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
  • HY-120833
    Ac-Ile-Glu-Thr-Asp-pNA

    		Caspase Others
    Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
  • HY-P1286
    PKC β pseudosubstrate

    		PKC Neurological Disease
    PKC β pseudosubstrate is a selective cell-permeable inhibitor of PKC .
  • HY-P4039
    Ac-EEVVAC-pNA

    		HCV Protease Infection
    Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
  • HY-P1103A
    CTCE-9908 TFA

    		CXCR Cancer
    CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
  • HY-P1321
    GR231118

    1229U91; GW1229

    		 Neuropeptide Y Receptor Neurological Disease
    GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
  • HY-P1286A
    PKC β pseudosubstrate TFA

    		PKC Neurological Disease
    PKC β pseudosubstrate TFA is a selective cell-permeable inhibitor of PKC .
  • HY-P1321A
    GR231118 TFA

    1229U91 TFA; GW1229 TFA

    		 Neuropeptide Y Receptor Neurological Disease
    GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
  • HY-P3215A
    Oxytocin parallel dimer TFA

    		Oxytocin Receptor Endocrinology
    Oxytocin parallel dimer TFA is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
  • HY-P3222A
    Oxytocin antiparallel dimer TFA

    		Peptides Endocrinology
    Oxytocin antiparallel dimer TFA is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
  • HY-P11735
    Suc-AAPP-pNA

    		Peptides Others
    Suc-AAPP-pNA is a protease substrate. (Sequence: Suc-Ala-Ala-Pro-Pro-pNA) .
  • HY-P11688
    Fmoc-PNA-M(Bhoc)-OH

    		Biochemical Assay Reagents Others
    Fmoc-PNA-M (Bhoc)-OH is a standard peptide nucleic acid (PNA) monomer building block. Fmoc-PNA-M (Bhoc)-OH carries two protecting groups, Fmoc and Bhoc, and is specifically designed for solid-phase and automated PNA synthesis. Fmoc-PNA-M (Bhoc)-OH efficiently participates in the construction of sequence-specific PNA probes. Through its protecting group strategy, Fmoc-PNA-M (Bhoc)-OH ensures the accuracy and efficiency of PNA synthesis, and is one of the important raw materials for PNA synthesis at present .
  • HY-P11681
    Boc-PNA-J(Z)-OH

    		DNA/RNA Synthesis Others
    Boc-PNA-J(Z)-OH is a protected peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Boc-PNA-J(Z)-OH features a 2,6-diaminopurine (J) base, protected by a carboxybenzyl (Z) group, attached to a Boc-protected aminoethylglycinate backbone. Boc-PNA-J(Z)-OH allows for the synthesis of PNA sequences with enhanced binding affinity and stability.
  • HY-P11686
    Fmoc-PNA-G(Boc)-OH

    		DNA/RNA Synthesis Others
    Fmoc-PNA-G(Boc)-OH is a synthetic peptide nucleic acid (PNA) modified with Fmoc and Boc protecting groups, designed for precise synthesis and targeted binding to complementary DNA or RNA sequences. Fmoc-PNA-G(Boc)-OH serves as a versatile tool in molecular biology, offering robustness, specificity, and applicability across various research and diagnostic fields.
  • HY-W540123
    Fmoc-PNA-A(Bhoc)-OH

    		Biochemical Assay Reagents Cancer
    Fmoc-PNA-A(Bhoc)-OH is a protected peptide nucleic acid (PNA) monomer carrying an adenine base. Fmoc-PNA-A(Bhoc)-OH contains Fmoc and benzhydryloxycarbonyl (Bhoc) protecting groups, and serves as a standard building block designed specifically for solid-phase PNA synthesis. Fmoc-PNA-A(Bhoc)-OH can be efficiently used to synthesize PNA-based sequence-specific hybridization probes. These probes have broad applications in molecular biology research; for example, they can be used in HER2-expressing tumor-related studies, providing tools for disease diagnosis and mechanism exploration .
  • HY-P11729
    Mitochondria rRNA blocker

    		Biochemical Assay Reagents Others
    Mitochondria rRNA blocker is a PCR blocker based on peptide nucleic acid (PNA). Mitochondria rRNA blocker targets the conserved 16S rRNA sequence of mitochondria and can be used in research involving PCR, sequencing, and gene detection.
  • HY-P11730
    Chloroplast rRNA blocker

    		Biochemical Assay Reagents Others
    Chloroplast rRNA blocker is a chloroplast rRNA-specific peptide nucleic acid (PNA) blocker. Chloroplast rRNA blocker targets the conserved 16S rRNA sequence in plants and can be used in research involving PCR, sequencing, and gene detection.
  • HY-P11698
    Guanidino-G-Clamp-PNA

    		DNA Alkylator/Crosslinker Transthyretin (TTR) Cancer
    Guanidino-G-Clamp-PNA is a highly efficient sequence-specific RNA binder and gene silencer. Guanidino-G-Clamp-PNA precisely targets such targets as miR-155 or transthyretin (TTR) mRNA through base pairing: the former regulates tumor-related signaling pathways by reducing microRNA activity, while the latter inhibits the translation of harmful proteins via steric hindrance. Guanidino-G-Clamp-PNA effectively stabilizes DNA/RNA duplexes, induces cancer cell apoptosis, and suppresses tumor growth. In addition, Guanidino-G-Clamp-PNA can be conjugated with targeting ligands to improve tissue-specific delivery and reduce in vivo adverse reactions, and it can also enhance the splicing regulation efficacy of other oligonucleotide platforms (such as PMO) when integrated into them. Guanidino-G-Clamp-PNA is applicable to the research of various diseases including diffuse large B-cell lymphoma and hereditary transthyretin-related amyloidosis .
  • HY-W784623
    Boc-PNA-A(Z)-OH

    		Drug Intermediate Others
    Boc-PNA-A(Z)-OH is a Boc-protected peptide nucleic acid monomer with a benzyloxycarbonyl protecting group on the adenine base .
  • HY-P11731
    Internal Transcribed Spacers (ITS) rRNA blocker

    		Biochemical Assay Reagents Infection
    Internal Transcribed Spacers (ITS) rRNA blocker is a peptide nucleic acid (PNA) blocker. Internal Transcribed Spacers (ITS) rRNA blocker binds and suppresses the amplification of the ITS2 rRNA region, a commonly overrepresented target sequence in fungal PCR. Internal Transcribed Spacers (ITS) rRNA blocker can be used in research involving PCR, sequencing, and gene detection.

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