27 Results for "

PNA sequence

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "PNA sequence" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-106262B
Purity:  99.73%
Synonyms: KAI-9803 hydrochloride; BMS-875944 hydrochloride
Target:  

PKC

Delcasertib (KAI-9803) hydrochloride is a potent and selective δ-protein kinase C (δPKC) inhibitor. Delcasertib (KAI-9803) hydrochloride could ameliorate injury associated with ischemia and reperfusion in animal models of acute myocardial infarction (MI) .
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1
1 Cited Publications
Cat. No.: HY-P1103
CAS No.: 1030384-98-5
Target:  

CXCR

Research Areas:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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1
1 Cited Publications
Cat. No.: HY-NP0182
Synonyms: PNA (Biotinylated)
Peanut Agglutinin (PNA) Biotinylated is a biotinylated lectin that specifically recognizes and binds to the Galβ1-3GalNAc sequence, thereby targeting SPESP1 and TF blood group antigens. As an acrosome-specific marker, Peanut Agglutinin Biotinylated stains mouse spermatocytes and sperm acrosomes with high specificity, and this binding depends not only on SPESP1 but also recognizes other testicular acrosomal glycoproteins. Peanut Agglutinin Biotinylated accurately identifies TF antigens in Reed-Sternberg cells, histiocytosis X cells, and esophageal squamous cell carcinoma, without cross-reacting with non-specific cells. Peanut Agglutinin Biotinylated maintains staining stability in both B-5 and formalin fixatives, and serves as an important tool for the study of Hodgkin's disease, histiocytosis X, and various malignant tumors .
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Cat. No.: HY-106262
CAS No.: 949100-39-4
Synonyms: KAI-9803; BMS-875944
Target:  

PKC

Delcasertib (KAI-9803) is a potent and selective δ-protein kinase C (δPKC) inhibitor. Delcasertib (KAI-9803) could ameliorate injury associated with ischemia and reperfusion in animal models of acute myocardial infarction (MI) .
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Cat. No.: HY-P3215
CAS No.: 19645-28-4
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
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Cat. No.: HY-P3222
CAS No.: 20054-93-7
Target:  

Peptides

Research Areas:  

Endocrinology

Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
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Cat. No.: HY-120833
CAS No.: 219138-21-3
Purity:  99.90%
Target:  

Caspase

Research Areas:  

Others

Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
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Cat. No.: HY-P1286
CAS No.: 172308-76-8
Target:  

PKC

Research Areas:  

Neurological Disease

PKC β pseudosubstrate is a selective cell-permeable inhibitor of PKC .
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Cat. No.: HY-NP0138
Synonyms: PNA (Fluorescein)
Peanut Agglutinin (PNA) Fluorescein is a fluorescently labeled lectin that specifically binds to glycosylated cells and Haemonchus contortus. Peanut Agglutinin Fluorescein specifically recognizes and binds to the D-Gal-β(1→3)-D-GalNAc disaccharide sequence and terminal D-galactosyl residues on the cell surface; its binding can be inhibited by D-galactose but is not affected by glucose. Peanut Agglutinin Fluorescein specifically labels cone photoreceptor segments and can also be used to distinguish immature thymocytes from lymphocyte subsets, serving as an effective tool for studying cellular glycosylation status and isolating specific cell populations .
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Cat. No.: HY-P4039
CAS No.: 389868-12-6
Target:  

HCV Protease

Research Areas:  

Infection

Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
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Cat. No.: HY-137858
CAS No.: 125455-61-0
Synonyms: Gly-Arg-4-NA hydrochloride; GR-PNA hydrochloride; GR p-itoailide hydrochloride
H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .
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Cat. No.: HY-P1103A
Target:  

CXCR

Research Areas:  

Cancer

CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Cat. No.: HY-P1321
CAS No.: 158859-98-4
Synonyms: 1229U91; GW1229
Research Areas:  

Neurological Disease

GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
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Cat. No.: HY-P1286A
Target:  

PKC

Research Areas:  

Neurological Disease

PKC β pseudosubstrate TFA is a selective cell-permeable inhibitor of PKC .
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Cat. No.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
Research Areas:  

Neurological Disease

GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
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Cat. No.: HY-P3215A
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

Oxytocin parallel dimer TFA is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
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Cat. No.: HY-P3222A
Target:  

Peptides

Research Areas:  

Endocrinology

Oxytocin antiparallel dimer TFA is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .
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Cat. No.: HY-P11735
Target:  

Peptides

Research Areas:  

Others

Suc-AAPP-pNA is a protease substrate. (Sequence: Suc-Ala-Ala-Pro-Pro-pNA) .
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Cat. No.: HY-P11688
Research Areas:  

Others

Fmoc-PNA-M (Bhoc)-OH is a standard peptide nucleic acid (PNA) monomer building block. Fmoc-PNA-M (Bhoc)-OH carries two protecting groups, Fmoc and Bhoc, and is specifically designed for solid-phase and automated PNA synthesis. Fmoc-PNA-M (Bhoc)-OH efficiently participates in the construction of sequence-specific PNA probes. Through its protecting group strategy, Fmoc-PNA-M (Bhoc)-OH ensures the accuracy and efficiency of PNA synthesis, and is one of the important raw materials for PNA synthesis at present .
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Cat. No.: HY-P11681
CAS No.: 163081-03-6
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Boc-PNA-J(Z)-OH is a protected peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Boc-PNA-J(Z)-OH features a 2,6-diaminopurine (J) base, protected by a carboxybenzyl (Z) group, attached to a Boc-protected aminoethylglycinate backbone. Boc-PNA-J(Z)-OH allows for the synthesis of PNA sequences with enhanced binding affinity and stability.
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