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Reductase Enzymes (DT-diaphorase

" in MedChemExpress (MCE) Product Catalog:
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Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-118722
    RB-90740

    		DNA/RNA Synthesis Cytochrome P450 Cancer
    RB-90740 is a type of biological reducing agent. RB-90740 is activated through metabolic reduction and generates cytotoxic products, thereby selectively killing tumor cells (usually in a hypoxic environment). RB-90740 has selective toxicity towards hypoxic cells, which is mainly achieved by causing DNA strand breaks and activating reducing enzymes (such as Cytochrome P450). RB-90740 does not initially exhibit cytotoxicity similar to its in vitro properties in hypoxic cells in mouse models. RB-90740 can be used to study the tumor physiological environment
    RB-90740

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