20 Results for "

SCEs

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "SCEs" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W017113
CAS No.: 149-30-4
2-Mercaptobenzothiazole is an activator of the aryl hydrocarbon receptor (AhR) , inhibiting thyroid hormone synthesis and dopamine beta-hydroxylase activity . 2-Mercaptobenzothiazole promotes bladder cancer cell invasion by altering the conformation of the AhR ligand binding domain (LBD), activating AhR transcription, and upregulating the mRNA and protein expression of target genes CYP1A1 and CYP1B1 . 2-Mercaptobenzothiazole inhibits thyroid peroxidase (TPO) with an IC50 value of 11.5 μM, induces histological changes such as follicular cell hypertrophy in Xenopus laevis tadpoles, delaying metamorphosis . 2-Mercaptobenzothiazole increases chromosomal aberrations and sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells, and enhances carcinogenicity in F344/N rats . 2-Mercaptobenzothiazole inhibits norepinephrine synthesis in mice and completely blocks the conversion of exogenous dopamine to norepinephrine in rat cardiomyocytes .
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1 Cited Publications
Cat. No.: HY-108539A
CAS No.: 1593478-56-8
Purity:  ≥99.0%
Target:  

Ras

Research Areas:  

Metabolic Disease

(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4 .
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Cat. No.: HY-13588
CAS No.: 52152-93-9
Purity:  97.33%
Synonyms: SCE-129 sodium
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
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Cat. No.: HY-113735
CAS No.: 97468-37-6
Purity:  ≥98.0%
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cephapirin hemibenzathine is an intrauterine-administered, long-acting cephalosporin antibiotic suitable for the anaerobic environment of the postpartum uterus. Cephapirin hemibenzathine effectively improves the recovery of postpartum buffaloes with subclinical endometritis (SCE) and enhances their reproductive performance. Cephapirin hemibenzathine can be used for the study of subclinical endometritis in postpartum buffaloes .
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Cat. No.: HY-B0734A
CAS No.: 66309-69-1
Synonyms: SCE-963 hydrochloride
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cefotiam (SCE-963) hydrochloride is a parenteral cephalosporin antibiotic. Cefotiam hydrochloride has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
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Cat. No.: HY-B0771A
CAS No.: 113981-44-5
Synonyms: SCE-2787 hydrochloride
Cefozopran (SCE-2787) hydrochloride is a potent antibiotic with broad-spectrum antibacterial activity. Cefozopran hydrochloride binds PBPs, induces cell wall destruction, cell elongation, filamentation, irregular septa formation, and bactericidal, bacteriolytic activity. Cefozopran hydrochloride reduces bacterial counts and eradicates bacteria in mouse respiratory, urinary, and thigh muscle infections. Cefozopran hydrochloride can be used for the research of bacterial infections .
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Cat. No.: HY-B0875
CAS No.: 75738-58-8
Synonyms: SCE-1365 hydrochloride
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
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Cat. No.: HY-163384
CAS No.: 2378384-49-5
Target:  

Dopamine Transporter

Research Areas:  

Neurological Disease

(S)-CE-123 is a potent, selective, and novel atypical dopamine transporter (DAT) inhibitor with an EC50 of 2.76 μM in uptake inhibition assays conducted in HEK293 cells stably expressing human isoforms of DAT. (S)-CE-123, a Modafinil analogue, is able to penetrate the blood–brain barrier. (S)-CE-123 improves cognitive and motivational processes in experimental animals .
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Cat. No.: HY-B0771
CAS No.: 113359-04-9
Synonyms: SCE-2787
Cefozopran (SCE-2787) is a potent antibiotic with broad-spectrum antibacterial activity. Cefozopran binds PBPs, induces cell wall destruction, cell elongation, filamentation, irregular septa formation, and bactericidal, bacteriolytic activity. Cefozopran reduces bacterial counts and eradicates bacteria in mouse respiratory, urinary, and thigh muscle infections. Cefozopran can be used for the research of bacterial infections .
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Cat. No.: HY-N3918
CAS No.: 524-15-2
γ-Fagarine is a furoquinoline alkaloid naturally occurring in Rutae Herba. γ-Fagarine has strong anti-HCV activities with IC50 of 20.4 μg/mL and is also a sister chromatid exchanges (SCEs) inducer .
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Cat. No.: HY-13588A
CAS No.: 62587-73-9
Synonyms: SCE-129
Target:  

Bacterial Antibiotic

Research Areas:  

Others

Cefsulodin (SCE-129) showed potent activity against Pseudomonas aeruginosa and strains susceptible to penicillin and gentamicin, with effectiveness comparable to that of gentamicin and debendazole. However, its effectiveness was diminished against penicillin-resistant strains of P. aeruginosa, particularly strains that were also resistant to gentamicin. For P. aeruginosa maltofila, SCE-129 showed similar minimum inhibitory concentrations to penicillin, gentamicin, and debendazole. Pseudomonas cepacia strains generally showed moderate resistance to SCE-129 and penicillin, and high resistance to gentamicin and debendazole .
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Cat. No.: HY-B0734
CAS No.: 61622-34-2
Synonyms: SCE-963; Cefotiam Dihydrochloride
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cefotiam (SCE-963) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
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Cat. No.: HY-B0875A
CAS No.: 65085-01-0
Synonyms: SCE-1365
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
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Cat. No.: HY-W770956
Synonyms: SCE-963-15N2; Cefotiam Dihydrochloride-15N2
Cefotiam- 13C, 15N2 (SCE-963- 13C, 15N2) is the 13C- and 15N-labeled Cefotiam (HY-B0734). Cefotiam (SCE-963) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
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Cat. No.: HY-B0734B
Synonyms: SCE-963 dihydrochloride hydrate
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cefotiam (SCE-963) dihydrochloride hydrate is a parenteral cephalosporin antibiotic. Cefotiam dihydrochloride hydrate has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
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Cat. No.: HY-B0771AR
CAS No.: 113981-44-5
Synonyms: SCE-2787 hydrochloride (Standard)
Cefozopran (SCE-2787) hydrochloride (Standard) is the analytical standard of Cefozopran hydrochloride. Cefozopran (SCE-2787) dihydrochloride is a potent antibiotic with broad-spectrum antibacterial activity. Cefozopran dihydrochloride binds PBPs, induces cell wall destruction, cell elongation, filamentation, irregular septa formation, and bactericidal, bacteriolytic activity. Cefozopran dihydrochloride reduces bacterial counts and eradicates bacteria in mouse respiratory, urinary, and thigh muscle infections. Cefozopran dihydrochloride can be used for the research of bacterial infections .
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Cat. No.: HY-B0875R
CAS No.: 75738-58-8
Synonyms: SCE-1365 hydrochloride (Standard)
Research Areas:  

Infection

Cefmenoxime (hydrochloride) (Standard) is the analytical standard of Cefmenoxime (hydrochloride). This product is intended for research and analytical applications. Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .
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Cat. No.: HY-13588B
CAS No.: 1426397-23-0
Synonyms: SCE-129 sodium hydrate
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
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Cat. No.: HY-13588R
CAS No.: 52152-93-9
Synonyms: SCE-129 sodium (Standard)
Research Areas:  

Infection

Cefsulodin (sodium) (Standard) is the analytical standard of Cefsulodin (sodium). This product is intended for research and analytical applications. Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM .
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Cat. No.: HY-W740077
CAS No.: 1262200-57-6
Synonyms: SCE-2787 dihydrochloride
Cefozopran (SCE-2787) dihydrochloride is a potent antibiotic with broad-spectrum antibacterial activity. Cefozopran dihydrochloride binds PBPs, induces cell wall destruction, cell elongation, filamentation, irregular septa formation, and bactericidal, bacteriolytic activity. Cefozopran dihydrochloride reduces bacterial counts and eradicates bacteria in mouse respiratory, urinary, and thigh muscle infections. Cefozopran dihydrochloride can be used for the research of bacterial infections .
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