Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
335 Results for "
St
" in MedChemExpress (MCE) Product Catalog:
Products (335)
335 Results for "St" in MCE Product Catalog:
73
73 Publications Verification
Cat. No.: HY-50937
CAS No.: 894787-30-5
Target:
Research Areas:
ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 interferes with recruitment of IRAK1 and IRAK4 by MyD88, causing inhibition of IL-1β-mediated activation of NF-κB transcriptional activity .
21
21 Cited Publications
Cat. No.: HY-U00434
CAS No.: 890405-51-3
Research Areas:
3BDO is a IFITM3 modulator and mTOR activator with antiviral and autophagy-inhibiting effects. 3BDO exhibits inhibitory activity against porcine coronaviruses. 3BDO increases the protein abundance of IFITM3, inhibits virus-cell membrane fusion, and blocks viral entry. 3BDO inhibits the entry of transmissible gastroenteritis virus, porcine epidemic diarrhea virus, and porcine respiratory coronavirus into host cells. 3BDO can be used for research on porcine coronavirus infection .
14
Adarotene is an effective apoptosis inducer, which surprisingly produces DNA damage and exhibites a potent antiproliferative activity on a large panel of human tumor cells.
4
4 Cited Publications
Target:
Research Areas:
ST034307 is a potent and selective adenylyl cyclase 1 (AC1) inhibitor, with IC50 of 2.3 μM.
4
4 Cited Publications
Target:
Research Areas:
ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
4
4 Cited Publications
Target:
Research Areas:
ST-193 hydrochloride is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
4
4 Cited Publications
Target:
Research Areas:
Lith-O-Asp is a sialytransferase (ST) inhibitor, with IC50s of 12-37 μM.
3
Target:
Research Areas:
Tecovirimat (ST-246) is an orally bioavailable and selective compound against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus .
3
3 Cited Publications
Synonyms: St-246 monohydrate
Target:
Research Areas:
Tecovirimat (ST-246) monohydrate is the monohydrate form of Tecovirimat (HY-14805). Tecovirimat monohydrate is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat monohydrate is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat monohydrate targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat monohydrate exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat monohydrate could be used in the study for orthopoxvirus-induced diseases .
3
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P71340
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: StUB1; CLL-Associated Antigen KW-8; StIP1 Homology And U-Box Containing Protein 1; Antigen NY-CO-7; CHIP; StIP1 Homology And U-Box Containing Protein 1, E3 Ubiquitin Protein Ligase; SDCCAG7; Heat Shock Protein A Binding Protein 2 (C-Terminal); HSPABP2; St
2
2 Cited Publications
Cat. No.: HY-P77003
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL24; IL-4-Induced Secreted Protein; Prev. St16; Mob-5; Interleukin-24; MDA7; IL10B; Melanoma Differentiation Association Protein 7; IL-24; Suppression Of Tumorigenicity 16 Protein; C49A; Melanocyte-Associated Mda-7; FISP; MDA-7; Suppression Of Tumorigeni
2
2 Cited Publications
Cat. No.: HY-P7260
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL20; Chemokine (C-C Motif) Ligand 20; Prev. SCYA20; C-C Motif Chemokine 20; LARC; CC Chemokine LARC; MIP-3a; MIP-3-Alpha; St38; Exodus-1; CKb4; MIP3A; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20; Beta Chemokine Exodus-1; Liver And Activati
2
2 Cited Publications
Cat. No.: HY-P7263
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL20; Chemokine (C-C Motif) Ligand 20; Prev. SCYA20; C-C Motif Chemokine 20; LARC; CC Chemokine LARC; MIP-3a; MIP-3-Alpha; St38; Exodus-1; CKb4; MIP3A; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20; Beta Chemokine Exodus-1; Liver And Activati
1
1 Cited Publications
Synonyms: St-1435; Elcometrine
Target:
Research Areas:
Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive .
1
Target:
Research Areas:
ST1936 is a selective, nanomolar affinity 5-HT6 receptor agonist with Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively. ST1936 also shows moderate affinity (Ki of 300 nM) for human and rat α2 adrenergic receptor .
1
Target:
Research Areas:
alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI) is a member of alpha2,8-sialyltransferase (ST8Sia) family, is often used in biochemical studies. alpha-2,8-Sialyltransferase (CstII) catalyzes elongation of the α2,8-linked oligo/polysialic acid chain on the Sia residue transferred .
1
1 Cited Publications
Cat. No.: HY-P76094
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: St6GAL1; St6GalI; Prev. SIAT1; Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialyltransferase); Beta-Galactoside Alpha-2,6-Sialyltransferase 1; Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialytransferase); CDw75; Beta-Galactoside Alpha-(2,6)-Sialy
1
1 Cited Publications
Cat. No.: HY-P70615
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RL1; St2V; Interleukin 1 Receptor Like 1; Homolog Of Mouse Growth Stimulation-Expressed; DER4; Suppressor Of Tumorigenicity 2; St2; Interleukin 1 Receptor-Like 1 Isoform 2; T1; Interleukin 1 Receptor-Like 1 Isoform 1; Interleukin-1 Receptor-Like 1; Int
1
1 Cited Publications
Cat. No.: HY-P76370
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL6St; Interleukin Receptor Beta Chain; Interleukin 6 Cytokine Family Signal Transducer; Membrane Glycoprotein Gp130; Interleukin-6 Receptor Subunit Beta; IL6St Nirs Variant 5; Membrane Glycoprotein 130; IL6St Nirs Variant 2; IL-6RB; IL6St Nirs Variant 3
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
