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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
TMEM16A
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "TMEM16A" in MCE Product Catalog:
74
74 Publications Verification
Synonyms: C.I. 75535; Isoarnebin 4
12
12 Cited Publications
Target:
Research Areas:
CaCCinh-A01 is an inhibitor of both TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM, respectively.
3
3 Cited Publications
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Research Areas:
T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) .
1
1 Cited Publications
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Research Areas:
Eact is a selective and potent activator of TMEM16A, directly activates the TRPV1 channels in sensory nociceptors and produces itch, acute nociception and thermal hypersensitivity .
Cat. No.: HY-153508
CAS No.: 2098490-06-1
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Research Areas:
ANO1-IN-4 (Compound 10bm) is a reversible inhibitor for calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1) with an IC50 of 0.030 µM. ANO1-IN-4 exhibits good metabolic stability in rat liver microsomes. ANO1-IN-4 inhibits spontaneous contraction in mouse isolated ileum .
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MONNA is a potent transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with an IC50 of 80 nM. MONNA induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions .
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T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling .
Cat. No.: HY-171333
CAS No.: 2367645-32-5
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Research Areas:
TMEM16A modulator-1 is a calcium-activated chloride channel (CaCC) and TMEM16A modulator that enhances the activity of the calcium-activated chloride channel TMEM16A. TMEM16A modulator-1 can be used in the research of TMEM16A-related diseases, such as studies of respiratory system diseases .
Cat. No.: HY-P990337
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Research Areas:
Cat. No.: HY-176453
CAS No.: 28282-22-6
Synonyms: N066-0059
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Allobetulone (N066-0059) is a TMEM16A inhibitor (IC50: 0.24 µM). Allobetulone (N066-0059) can be used in anti-cancer research .
Cat. No.: HY-RS23781
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Ano1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ano1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00740
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Research Areas:
ANO1 Human Pre-designed siRNA Set A contains three designed siRNAs for ANO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-100612R
CAS No.: 552309-42-9
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Research Areas:
T16Ainh-A01 (Standard) is the analytical standard of T16Ainh-A01 (HY-100612). This product is intended for research and analytical applications. T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 μM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) .
Cat. No.: HY-103368R
CAS No.: 461000-66-8
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Research Areas:
Eact (Standard) is the analytical standard of Eact (HY-103368). This product is intended for research and analytical applications. Eact is a selective and potent activator of TMEM16A, directly activates the TRPV1 channels in sensory nociceptors and produces itch, acute nociception and thermal hypersensitivity .
Cat. No.: HY-P700616
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANO1; Transmembrane Protein 16A; Prev. TMEM16A; FLJ10261; Prev. ORAOV2; Transmembrane Protein 16A (Eight Membrane-Spanning Domains); TAOS2; Oral Cancer Overexpressed Protein 2; DOG1; Calcium Activated Chloride Channel; Discovered On Gastrointestinal Strom
Species:
Human
Source:
E. coli
Cat. No.: HY-100611R
CAS No.: 407587-33-1
Target:
Research Areas:
CaCCinh-A01 (Standard) is the analytical standard of CaCCinh-A01 (HY-100611). This product is intended for research and analytical applications. CaCCinh-A01 is an inhibitor of both TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM, respectively.
Cat. No.: HY-RS17326
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Research Areas:
Ano1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ano1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
