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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
TP-2
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "TP-2" in MCE Product Catalog:
Cat. No.: HY-157930
Target:
Research Areas:
TP-2, a caltrop-like multicationic small molecule, is an antidote that can completely neutralize both unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs). TP-2 is not only superior to protamine, has higher neutralization activity, but is also biocompatible .
Thiophene-2 (TP2) is a specific polyketide synthase 13 (Pks13) inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active against Mycobacterium tuberculosis with a MIC value of 1 μM, and has potent anti-tuberculosis activity .
Cat. No.: HY-RS14858
Target:
Research Areas:
TNP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TNP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14376
Target:
Research Areas:
Tert Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tert gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14375
Target:
Research Areas:
TERT Human Pre-designed siRNA Set A contains three designed siRNAs for TERT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P81110A
Synonyms: EST2; TCS1; TRT; TERT; Telomerase reverse transcriptase; HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2; TP2
Cat. No.: HY-176143
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
P2Y1/P2Y6 antagonist 1 (Compound 3h) is an indolesulfonylhydrazide derivative. P2Y1/P2Y6 antagonist 1 is an orally active tP2Y1 and rP2Y6 antagonist (IC50 of 9.72 and 1.89 μM, respectively). P2Y1/P2Y6 antagonist 1 can be used in the study of neurological diseases, inflammation, cardiovascular diseases and cancer .
Cat. No.: HY-183716
CAS No.: 2489184-70-3
Target:
Research Areas:
Mito-TP-2 is a triptolide (HY-32735) derivative. Mito-TP-2 exhibits concentration-dependent cytotoxicity in cancer cells. Mito-TP-2 is selectively driven and accumulated into the mitochondria of tumor cells by mitochondrial transmembrane potential and exerts specific mitochondrial toxicity. Mito-TP-2 can be used for the research of liver cancer, breast cancer, and non-small cell lung cancer [2] .
Cat. No.: HY-P704039
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TERT; Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; HEST2; PFBMFT1; TCS1; DKCA2; EST2; DKCB4; TRT; CMM9; TP2; HTRT
Species:
Human
Source:
E. coli
Cat. No.: HY-173211
Target:
Research Areas:
anti-TNBC agent-8 (Compound TP2) is a photodynamic therapeutic agent targeting mitochondrial DNA G4 (mtG4). Under white light irradiation, its IC50 against 4T1 cells is 0.42 μM. anti-TNBC agent-8 binds tightly to mtG4 and generates a large amount of reactive oxygen species (ROS) under white light irradiation, leading to the loss of mitochondrial membrane potential (MMP), a decrease in ATP production, and an increase in the ROS level. This, in turn, induces significant apoptosis in triple-negative breast cancer (TNBC) cells, exerting the activity of inhibiting tumor cell growth. anti-TNBC agent-8 can be used in the research of triple-negative breast cancer.
Cat. No.: HY-P703520
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TERT; Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; HEST2; PFBMFT1; TCS1; DKCA2; EST2; DKCB4; TRT; CMM9; TP2; HTRT
Species:
Others
Source:
E. coli
Cat. No.: HY-P703522
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TERT; Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; HEST2; PFBMFT1; TCS1; DKCA2; EST2; DKCB4; TRT; CMM9; TP2; HTRT
Species:
Others
Source:
E. coli
Cat. No.: HY-P703521
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TERT; Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; HEST2; PFBMFT1; TCS1; DKCA2; EST2; DKCB4; TRT; CMM9; TP2; HTRT
Species:
Others
Source:
E. coli
Cat. No.: HY-189078
CAS No.: 121573-36-2
Synonyms: 10,10-Difluorothromboxane A2; F2-TXA2
Target:
Prostaglandin Receptor Platelet-activating Factor Receptor (PAFR) mTOR Eukaryotic Initiation Factor (eIF) PKC Lipoxygenase
Research Areas:
10,10-Difluoro TXA2 (10,10-Difluorothromboxane A2; F2-TXA2) is a thromboxane A2/TP receptor agonist and induces platelet aggregation. 10,10-Difluoro TXA2 activates platelet α and vascular τ thromboxane/prostaglandin receptors, acts as a full agonist in platelet and vascular experiments, and promotes platelet activation, hemostasis, and smooth muscle contraction. 10,10-Difluoro TXA2 induces 12/15-LOX protein through mTOR/4EBP1/eIF4E-dependent translation and downstream PKCθ activation. 10,10-Difluoro TXA2 can be used for research on cardiovascular diseases .
Cat. No.: HY-P71919
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TIGAR; Probable Fructose-2,6-Bisphosphatase TIGAR; Prev. C12orf5; Chromosome 12 Open Reading Frame 5; TP53-Induced Glycolysis And Apoptosis Regulator; Transactivated By NS3TP2 Protein; Fructose-2,6-Bisphosphatase TIGAR; FR2BP; TP53-Induced Glycolysis Regu
Species:
Human
Source:
E. coli
Cat. No.: HY-P704742
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TOP2A; DNA Topoisomerase 2-Alpha; Prev. TOP2; DNA Topoisomerase II, 170 KD; TOP2alpha; DNA Topoisomerase 2; TOPIIA; DNA Gyrase; Topoisomerase (DNA) II Alpha 170kDa; TP2A; DNA Topoisomerase II, Alpha Isozyme; DNA Topoisomerase II Alpha; DNA Topoisomerase (
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
