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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
Transferrin Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "Transferrin Receptor" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P3267
CAS No.: 11096-37-0
1
1 Cited Publications
Cat. No.: HY-159569
CAS No.: 1643444-62-5
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TfR-1-IN-1 is a transferrin receptor-1 (TfR-1) inhibitor with tumor cell-specific activity. TfR-1-IN-1 reduces TfR-1 expression, impairs mitochondrial function, induces cell apoptosis, necroptosis and ferroptosis, and increases intracellular iron (II) levels. TfR-1-IN-1 decreases the metabolic activity of cancer cells. TfR-1-IN-1 can be used for the research of ovarian cancer, breast cancer and acute myeloid leukemia .
1
Cat. No.: HY-P9999
CAS No.: 2568868-35-7
Synonyms: RG6102; RO-7126209
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Cat. No.: HY-P991047
Synonyms: JR-141 antibody (uncoupled from iduronate 2-sulfatase)
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Cat. No.: HY-P990051
CAS No.: 2653183-66-3
Synonyms: AOC-1001 Antibody; AOC-1044 Antibody
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Cat. No.: HY-P99797
CAS No.: 2140211-48-7
Synonyms: JR-141
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Cat. No.: HY-P3267A
CAS No.: 11096-37-0
Cat. No.: HY-P2297
CAS No.: 344618-30-0
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Cat. No.: HY-P11099
CAS No.: 1254540-73-2
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Cat. No.: HY-D2426
Cat. No.: HY-P2314
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Cat. No.: HY-P991381
Synonyms: PPMX-T003; TSP-A18
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Cat. No.: HY-P990130
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Cat. No.: HY-P990856
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Cat. No.: HY-P10323
Synonyms: Tumstatin (74-98), human
Cat. No.: HY-173444
CAS No.: 2989934-63-4
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HDAC11-IN-3 (Compound A9) is a selective HDAC11 inhibitor (IC50: 4.1 nM). HDAC11-IN-3 has inhibitory effects on U937 and OCI-AML2 acute myeloid leukemia (AML) cell lines (IC50: 10 μM). HDAC11-IN-3 has significant anti-AML activity, inducing apoptosis, cell cycle arrest, and differentiation. HDAC11-IN-3 upregulates the iron transporters transferrin (TF) and transferrin receptor (TFRC), and activates the p62-Keap1-Nrf2-HMOX1 pathway, which together lead to increased intracellular iron levels and induce ferroptosis in AML cells. HDAC11-IN-3 can be used alone or in combination with Cytarabine (HY-13605) for AML research .
Cat. No.: HY-P10323A
Synonyms: Tumstatin (74-98), human TFA
Cat. No.: HY-P990791
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
