4 Results for "

acidic vacuoles

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "acidic vacuoles" in MCE Product Catalog:

Cat. No.: HY-D1629
CAS No.: 172646-19-4
Calcium Orange AM is an intracellular calcium reporter. Specific fluorescence can be detected when free calcium binds to Calcium Orange AM (Ex/Em=549/576 nm). Calcium Orange AM does not enter the vacuoles and does not compartmentalize into acidic vesicles .
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Cat. No.: HY-N10443
CAS No.: 5224-54-4
Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, reactive oxygen species (ROS) production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease .
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Cat. No.: HY-111287
CAS No.: 853136-76-2
Synonyms: DK-1-49
Target:  

Autophagy

Research Areas:  

Cancer

Autophagonizer (DK-1-49) is a small molecule autophagy inducer that results in an accumulation of autophagy-associated LC3-II and enhances levels of autophagosomes and acidic vacuoles. Autophagonizer inhibits cell viability and induces cell death in not only cancer cells but also Bax/Bak double-knockout cells with EC50 values of 3-4 μM .
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Cat. No.: HY-149590
CAS No.: 200348-48-7
Target:  

Phosphatase

Research Areas:  

Others

IPA is a specific Sec18/NSF inhibitor. IPA binds to phosphatidic acid competitively, induces conformational rigidification of Sec18/NSF, disrupts its essential flexibility, and blocks SNARE priming and vacuolar membrane fusion. IPA can be used to investigate the activity of Sec18 and SNARE priming kinetics .
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