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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
basic conditions
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "basic conditions" in MCE Product Catalog:
2
Cat. No.: HY-W250143
CAS No.: 6586-04-5
Cat. No.: HY-W848699
CAS No.: 890090-41-2
Cat. No.: HY-W141765
CAS No.: 870487-04-0
Target:
Research Areas:
Fmoc-Cit-PAB-OH is a peptide linker containing an Fmoc-protected amine and citrulline residue. The Fmoc group can be deprotected under basic conditions to obtain the free amine, which can be used for further conjugations.
Cat. No.: HY-118112
CAS No.: 64191-06-6
Target:
Research Areas:
4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
Cat. No.: HY-W591439
CAS No.: 870487-07-3
Target:
Research Areas:
Fmoc-Lys(Boc)-PAB-PNP is a Boc-protected Lysine linked to 4-aminobenzoiate (PAB) with terminal Fmoc and PNP groups. The Fmoc group can be deprotected under basic conditions to release the free amine which can be used for further conjugations.
Cat. No.: HY-144011
CAS No.: 1246304-74-4
DSPE-PEG-Cyanur ammonium is a PEG derivative containing cyanur functional group. DSPE-PEG-Cyanur ammonium can be used for PEGylation of protein under mild basic conditions. DSPE-PEG-Cyanur ammonium can be used for nanostructured lipid carrier .
Cat. No.: HY-W739603
CAS No.: 252255-42-8
Cat. No.: HY-135593
CAS No.: 183060-99-3
Target:
Research Areas:
LY88074 analog 1 is a benzothiophene compound with nitrogen-containing non-basic side chains, Compound 26, extracted from patent EP0747380A1. LY88074 analog 1 is an agent for alleviating the symptoms of post-menopausal symptoms, such as osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. LY88074 analog 1 can be used alone or in combination with estrogen or progestin .
Cat. No.: HY-D1291
CAS No.: 2255329-06-5
Cat. No.: HY-D1291A
CAS No.: 2255329-07-6
Cat. No.: HY-W590561
CAS No.: 2241747-15-7
Target:
Research Areas:
Fmoc-Asp(biotinyl-PEG)-OH is a biotinylation reagent with a Fmoc-protected amino group. The Fmoc group can be deprotected under basic conditions to obtain the free amine which can be used for further conjugations.
Cat. No.: HY-W591441
CAS No.: 1491136-21-0
Target:
Research Areas:
Fmoc-Ala-PAB-PNP is an Alanine linked to 4-aminobenzoiate (PAB) with terminal Fmoc and PNP groups. The Fmoc group can be deprotected under basic conditions to release the free amine which can be used for further conjugations. PNP is a good leaving group when reacting with an amine-bearing payload.
Cat. No.: HY-W591440
CAS No.: 870487-05-1
Target:
Research Areas:
Fmoc-Cit-PAB-PNP is a Citrulline linked to 4-aminobenzoiate (PAB) with terminal Fmoc and PNP groups. The Fmoc group can be deprotected under basic conditions to release the free amine which can be used for further conjugations. PNP group is a good leaving group when reacting with an amine-bearing payload.
Cat. No.: HY-W190948
CAS No.: 905735-81-1
Target:
Research Areas:
10-(tert-Butoxy)-10-oxodecanoic NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.
Cat. No.: HY-W190906
CAS No.: 402958-62-7
Target:
Research Areas:
6-(tert-Butoxy)-6-oxohexanoic NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.
Cat. No.: HY-D3099
CAS No.: 3078752-74-3
Target:
Research Areas:
CSMPP is a ratiometric lysosomal pH fluorescent probe with aggregation-induced emission (AIE) properties, which is used for real-time quantitative detection of lysosomal pH changes in living cells and in vivo. CSMPP has a cyanodistyrene backbone, and contains N-methylpiperazine and pyridine groups (pH-responsive); protonation of the pyridine group significantly enhances intramolecular charge transfer (ICT), leading to green fluorescence emission (Ex/Em = 405/503 nm) under neutral/basic conditions and red fluorescence emission (Ex/Em = 405/615 nm) under acidic conditions. CSMPP exhibits high selectivity, reversibility, good biocompatibility and excellent photostability .
Cat. No.: HY-W190920
CAS No.: 2411681-93-9
Target:
Research Areas:
t-Butoxycarbonyl-PEG2-NHS ester has a t-Boc protecting group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Cat. No.: HY-W190720
CAS No.: 1263044-77-4
Target:
Research Areas:
Fmoc-NH-PEG4-HZ-BOC is a PEG reagent containing an Fmoc-protected amine and a Boc-protected hydrazide. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
