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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
cancer osaka thyroid
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "cancer osaka thyroid" in MCE Product Catalog:
Cat. No.: HY-169153
CAS No.: 1984784-12-4
Target:
Research Areas:
Cot inhibitor-3 (Compound 33) is a potent and selective cancer osaka thyroid (COT) kinase inhibitor, with an IC50 of 4 nM. Cot inhibitor-3 can be used to prevent inflammation-driven lameness .
Cat. No.: HY-159074
CAS No.: 1798303-75-9
Target:
Research Areas:
Cot-IN-5 (compound 1) is a potent ATP-competitive inhibitor of cancer osaka thyroid (COT). Cot-IN-5 can block COT kinase autophosphorylation .
Cat. No.: HY-P75921
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K8; Proto-Oncogene Serine/Threoine Protein Kinase; Prev. ESTF; Cot (cancer osaka thyroid) Oncogene; Prev. COT; Serine/Threonine-Protein Kinase Cot; Tumor Progression Locus 2; cancer osaka thyroid Oncogene; Tpl-2; Ewing Sarcoma Transformant; C-COT; AUR
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-178726
CAS No.: 1984784-10-2
Target:
Research Areas:
Cot-IN-4 (compound 32) is a potent cancer osaka thyroid (COT) kinase inhibitor with an IC50 of 6 nM. Cot-IN-4 inhibits the phosphorylation of ERK (IC50: 60 nM) and inhibits TNFα release (IC50: 60 nM). Cot-IN-4 also inhibits the formation of the pro-inflammatory cytokine IL-1β (IC50: 0.2 μM) in Uric acid (HY-B2130)-stimulated macrophages. Cot-IN-4 can be used for the study of inflammatory diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
