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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
cathepsin Z
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "cathepsin Z" in MCE Product Catalog:
16
16 Publications Verification
Synonyms: Z-FL-COCHO
Target:
Research Areas:
LY 3000328 (Z-FL-COCHO) is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively.
12
12 Cited Publications
Synonyms: Z-Phe-Tyr-CHO
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Z-FY-CHO (Z-Phe-Tyr-CHO) is a potent and specific cathepsin L (CTSL) inhibitor .
10
Z-FA-FMK ((1S)-Z-FA-FMK) is a potent Cathepsin B and L inhibitor. Z-FA-FMK blocks the induction of DEVDase activity, DNA fragmentation, and externalization of phosphatidylserine by selective synthetic retinoid-related molecules (RRMs). Z-FA-FMK inhibits apoptosis. Z-FA-FMK inhibits caspase activity and selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Z-FA-FMK is a viral inhibitor. Z-FA-FMK inhibits reovirus replication in a susceptible host .
5
2
2 Cited Publications
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2
2 Cited Publications
Cat. No.: HY-P4217
CAS No.: 201928-42-9
1
1 Cited Publications
Synonyms: (Rac)-Z-Phe-Phe-FMK
Cathepsin L-IN-2 ((Rac)-Z-Phe-Phe-FMK) is a Cathepsin L (CTSL) inhibitor. Cathepsin L-IN-2 inhibits CTSL enzymatic activity, supporting the mechanism by which CTSL mediates T-DXd linker cleavage and payload release. Cathepsin L-IN-2 is used in studies on Cathepsin L-dependent ADC payload release and breast cancer-related mechanisms .
1
1 Cited Publications
Research Areas:
Z-Leu-Arg-AMC is a fluorogenic peptide substrate for cysteine proteases (e.g., Cathepsin) (Ex=350 nm，Em=460 nm). Z-Leu-Arg-AMC is preferentially cleaved by Cathepsin K and S under weakly acidic conditions, while its hydrolysis relies on residual Cathepsin S activity at neutral pH. Z-Leu-Arg-AMC serves as a substrate for recombinant Sphenophorus levis Cathepsin L, falcipain-2, falcipain-3, berghepain-2, knowlepain-2, vivapain-2, as well as falcipain-2 chimeras and constructs. It enables quantitative detection of cysteine protease activity in human inflammatory bronchoalveolar lavage fluid via fluorescence generation. Z-Leu-Arg-AMC can be used in research related to pulmonary inflammatory diseases and malaria .
1
1 Cited Publications
Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection .
1
1 Cited Publications
Cat. No.: HY-P7758
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSZ; cathepsin IV; cathepsin Z; cathepsin B2; cathepsin X; cathepsin Z1; CTSX; cathepsin Y; Cysteine-Type Carboxypeptidase; cathepsin P; Lysosomal Carboxypeptidase B; Preprocathepsin P; Carboxypeptidase LB
Species:
Human
Source:
HEK293
Cat. No.: HY-P1759
CAS No.: 65147-22-0
Synonyms: Z-FR-AMC
Synonyms: Z-Phe-Phe-FMK
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Cat. No.: HY-P1759A
CAS No.: 70382-26-2
Synonyms: Z-FR-AMC hydrochloride
Cat. No.: HY-42709
CAS No.: 24787-89-1
Synonyms: Carbobenzoxy-L-valyl-L-alanine
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Cat. No.: HY-W790014
CAS No.: 180313-86-4
Cat. No.: HY-P4306
CAS No.: 65178-14-5
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Cat. No.: HY-W796158
CAS No.: 250584-13-5
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Cat. No.: HY-P4500
CAS No.: 122630-71-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
