cell suspension cultures

Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

By Targets:	Biochemical Assay Reagents (2) Collagen (1) Drug Derivative (2) Endogenous Metabolite (2) HIV (1) Insecticide (1) Phytohormone (1) Reference Standards (1)
By Research Areas:	Infection (2) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (1)

Targets Recommended: Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor BCL6 Tim3 VISTA BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131577A

Neutral protease I Dispase I	Collagen	Others
Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .

HY-N2188

Beta-Acetoxyisovalerylshikonin 1 Publications Verification	HIV	Infection
Beta-Acetoxyisovalerylshikonin is a naturally occurring naphthoquinone-type shikonin derivative that is widely distributed in the roots and cell suspension cultures of Arnebia euchroma, Arnebia guttata, Onosma hispidum and Lithospermum erythrorhizon. Beta-Acetoxyisovalerylshikonin exhibits favorable antibacterial, anti-inflammatory, wound-healing promoting and antioxidant activities, and also possesses potential anti-tumor and anti-HIV properties .

HY-W004494

2-Aminoindan-2-phosphonic acid 1 Publications Verification	Biochemical Assay Reagents	Others
2-Aminoindan-2-phosphonic acid is an inhibitor of phenylalanine ammonia-lyase (PAL). 2-Aminoindan-2-phosphonic acid reduces the biosynthesis and accumulation of total phenolic compounds in the suspension cell culture system of Cistanche .

HY-W134423B

Agar, meets USP testing specifications	Biochemical Assay Reagents	Others
Agar, meets USP testing specifications is a high-quality selective growth support and substrate for non-adherent cells. Agar, meets USP testing specifications effectively supports the growth, colony formation and metachromatic matrix production of chondrocytes, and also facilitates the isolation and differentiation of pure chondrocyte strains by restricting the proliferation of fibroblast-like cells. Chondrocytes grown in Agar, meets USP testing specifications can be successfully transferred to a liquid suspension culture system, where they continue to proliferate while retaining the characteristics exhibited during growth in agar .

HY-N0229R

L-Alanine (Standard) L-2-Aminopropionic acid (Standard)	Reference Standards Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine (Standard) is the analytical standard of L-Alanine. This product is intended for research and analytical applications. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. In Vitro: The viability of both hiPSCs, 201B7 cells and ehiPSCs decrease with an increase in L-Alanine concentration, and reach 7.5±1.3% and 3.7±0.7% respectively at 1.2 M of L-Alanine. On the other hand, no decrease in the viability of hFBs and hSkMCs are observed. Although the viability of iCMs slightly decreases along with the increase of the L-Alanine concentration, viability of iCMs at 1.2 M concentration of L-Alanine, 49.4±6.9%, is significantly higher than that of undifferentiated iPSCs, 201B7 cells and ehiPSCs (p< 0.01). The viability of hiPSCs, 201B7 cells and ehiPSCs, drastically decrease even after 2 or 4 h treatment. In contrast, the viability of hFBs fails to decrease at 1, 2, and 4 h and shows a small decrease at 24 h treatment. The viability of 201B7 cells in suspension culture decreases to 11.8±6.0% following treatment with 1.2 M L-Alanine for 2 h, whereas that of hFBs is 72.9±14.2% .

HY-P10400A

AtPep1 TFA	Phytohormone	Infection
AtPep1 TFA is an endogenous inducer of innate immune responses. AtPep1 TFA can be isolated from Arabidopsis thaliana leaves. AtPep1 TFA activates the transcription of defensin (PDF1.2), the expression of PROPEP1, the synthesis of hydrogen peroxide (H₂O₂) near leaf veins, and the alkalization of Arabidopsis suspension cell culture medium. AtPep1 TFA induces the expression of genes encoding defensins and PR-1. AtPep1 TFA is applicable to studies related to Pythium irregulare infection and pathogen infection .

HY-N12748

17βH-Gitoxigenin	Others	Others
17βH-Gitoxigenin is a compound that can be isolated from cell suspension cultures of Stropanthus divaricatus .

HY-N15731

Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside	Drug Derivative	Inflammation/Immunology
Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside (Compound 5) is an orally active cyanidin triglycoside derivative found in carrot cell suspension cultures. Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside is promising for research of natural pigment stability, antioxidant mechanisms, and oxidative stress-related diseases (e.g., inflammation) .

HY-N17915

2-Methyl-3,5,6-trihydroxyanthraquinone	Others	Others
2-Methyl-3,5,6-trihydroxyanthraquinone (compound 6) is an anthraquinone found in cell suspension cultures of Morinda citrifolia .

HY-107852

Demeton-S-methyl sulfone	Insecticide	Others
Demeton-S-methyl sulfone is an organophosphorus insecticide metabolite.Demeton-S-methyl sulfone serves as a substrate for metabolic breakdown.Demeton-S-methyl sulfone forms via oxidation of demeton S-methyl sulfoxide in sugar-beet cell suspension cultures.Demeton-S-methyl sulfone undergoes thioester bond cleavage, producing ethanethiols that convert into S-methylated compounds or S-glucosides .

HY-W726472

N-(E-4-Coumaroyl)-aspartate	Endogenous Metabolite	Others
N-(E-4-Coumaroyl)-aspartate is a hydroxycinnamic acid amide compound that can be isolated from Arabidopsis thaliana cell suspension cultures. N-(E-4-Coumaroyl)-aspartate may be involved in metabolic processes related to specific metabolites found in Arabidopsis thaliana cell cultures.

HY-N16838

cis-Oxyresveratrol-4'-O-glucoside	Drug Derivative	Inflammation/Immunology
cis-Oxyresveratrol-4'-O-glucoside (compound 2a) is a β-D-glucoside derivative of oxyresveratrol, whose parent compound possesses potential anti-inflammatory, antioxidant, free radical scavenging, and tyrosinase inhibitory activities, and can be used in anti-inflammatory, antioxidant, and whitening-related research. cis-Oxyresveratrol-4'-O-glucoside is a product obtained by the biotransformation of oxyresveratrol using cell suspension cultures of Solanum mammosum (a plant of the genus Solanum in the Solanaceae family) .

Cat. No.	Product Name	Type

HY-W134423B

Agar, meets USP testing specifications	Biochemical Assay Reagents
Agar, meets USP testing specifications is a high-quality selective growth support and substrate for non-adherent cells. Agar, meets USP testing specifications effectively supports the growth, colony formation and metachromatic matrix production of chondrocytes, and also facilitates the isolation and differentiation of pure chondrocyte strains by restricting the proliferation of fibroblast-like cells. Chondrocytes grown in Agar, meets USP testing specifications can be successfully transferred to a liquid suspension culture system, where they continue to proliferate while retaining the characteristics exhibited during growth in agar .

Agar, meets USP testing specifications

Biochemical Assay Reagents

Agar, meets USP testing specifications is a high-quality selective growth support and substrate for non-adherent cells. Agar, meets USP testing specifications effectively supports the growth, colony formation and metachromatic matrix production of chondrocytes, and also facilitates the isolation and differentiation of pure chondrocyte strains by restricting the proliferation of fibroblast-like cells. Chondrocytes grown in Agar, meets USP testing specifications can be successfully transferred to a liquid suspension culture system, where they continue to proliferate while retaining the characteristics exhibited during growth in agar .

Cat. No.	Product Name	Target	Research Area

HY-P10400A

AtPep1 TFA	Phytohormone	Infection
AtPep1 TFA is an endogenous inducer of innate immune responses. AtPep1 TFA can be isolated from Arabidopsis thaliana leaves. AtPep1 TFA activates the transcription of defensin (PDF1.2), the expression of PROPEP1, the synthesis of hydrogen peroxide (H₂O₂) near leaf veins, and the alkalization of Arabidopsis suspension cell culture medium. AtPep1 TFA induces the expression of genes encoding defensins and PR-1. AtPep1 TFA is applicable to studies related to Pythium irregulare infection and pathogen infection .

Cat. No.	Product Name

HY-K2004

Trypan Blue Staining Solution (0.4%)
MCE Trypan Blue Staining Solution (0.4%) is suitable for viability assessment of most adherent and suspension cell lines. It is commonly used for cell culture quality control, evaluation of cellular responses following drug treatment, and viability measurements after cell thawing and recovery.

HY-K6503

Human PSC Embryoid Body (EB) Induction Medium
MCE Human PSC Embryoid Body (EB) Induction Medium is specifically designed to support the efficient and reproducible formation of uniform embryoid bodies from pluripotent stem cells under suspension culture conditions. This optimized culture system integrates microenvironmental regulation with metabolic adaptation strategies, significantly improving the stability and reproducibility of EB formation.

Human PSC Embryoid Body (EB) Induction Medium

MCE Human PSC Embryoid Body (EB) Induction Medium is specifically designed to support the efficient and reproducible formation of uniform embryoid bodies from pluripotent stem cells under suspension culture conditions. This optimized culture system integrates microenvironmental regulation with metabolic adaptation strategies, significantly improving the stability and reproducibility of EB formation.

HY-K3028

Advanced MEM Reduced Serum Medium
MCE Advanced MEM Reduced Serum Medium is a chemically defined essential medium developed based on classical MEM formulation. Enables at least a 50% reduction in fetal bovine serum (FBS) usage while maintaining normal cell growth rates and cellular morphology, and is suitable for the culture of a wide variety of suspension and adherent mammalian cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2188

Beta-Acetoxyisovalerylshikonin 1 Publications Verification	Structural Classification Classification of Application Fields Plants Naphthalene Quinones Boraginaceae Quinones other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields Arnebia euchroma (Royle) Johnst. Source Classification	HIV
Beta-Acetoxyisovalerylshikonin is a naturally occurring naphthoquinone-type shikonin derivative that is widely distributed in the roots and cell suspension cultures of Arnebia euchroma, Arnebia guttata, Onosma hispidum and Lithospermum erythrorhizon. Beta-Acetoxyisovalerylshikonin exhibits favorable antibacterial, anti-inflammatory, wound-healing promoting and antioxidant activities, and also possesses potential anti-tumor and anti-HIV properties .

HY-N0229R

L-Alanine (Standard) L-2-Aminopropionic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Disease markers Amino acids Endogenous metabolite Cancer Source Classification	Reference Standards Endogenous Metabolite
L-Alanine (Standard) is the analytical standard of L-Alanine. This product is intended for research and analytical applications. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. In Vitro: The viability of both hiPSCs, 201B7 cells and ehiPSCs decrease with an increase in L-Alanine concentration, and reach 7.5±1.3% and 3.7±0.7% respectively at 1.2 M of L-Alanine. On the other hand, no decrease in the viability of hFBs and hSkMCs are observed. Although the viability of iCMs slightly decreases along with the increase of the L-Alanine concentration, viability of iCMs at 1.2 M concentration of L-Alanine, 49.4±6.9%, is significantly higher than that of undifferentiated iPSCs, 201B7 cells and ehiPSCs (p< 0.01). The viability of hiPSCs, 201B7 cells and ehiPSCs, drastically decrease even after 2 or 4 h treatment. In contrast, the viability of hFBs fails to decrease at 1, 2, and 4 h and shows a small decrease at 24 h treatment. The viability of 201B7 cells in suspension culture decreases to 11.8±6.0% following treatment with 1.2 M L-Alanine for 2 h, whereas that of hFBs is 72.9±14.2% .

HY-N12748

17βH-Gitoxigenin	Apocynaceae Structural Classification Cardiacglycosides Strophanthus divaricatus (Lour.) Hook. & Arn. Plants Steroids Source Classification	Others
17βH-Gitoxigenin is a compound that can be isolated from cell suspension cultures of Stropanthus divaricatus .

HY-N15731

Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside	Structural Classification Anthocyans Flavonoids Simple Phenylpropanols Phenylpropanoids Artemisia granatensis boiss Umbelliferae Plants Source Classification	Drug Derivative
Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside (Compound 5) is an orally active cyanidin triglycoside derivative found in carrot cell suspension cultures. Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside is promising for research of natural pigment stability, antioxidant mechanisms, and oxidative stress-related diseases (e.g., inflammation) .

HY-N17915

2-Methyl-3,5,6-trihydroxyanthraquinone	Quinones Structural Classification Anthraquinones Morinda citrifolia Linn. Rubiaceae Plants Source Classification	Others
2-Methyl-3,5,6-trihydroxyanthraquinone (compound 6) is an anthraquinone found in cell suspension cultures of Morinda citrifolia .

HY-W726472

N-(E-4-Coumaroyl)-aspartate	Structural Classification Monophenols Arabidopsis thaliana (L.) Heynh. Phenols Plants Brassicaceae Source Classification	Endogenous Metabolite
N-(E-4-Coumaroyl)-aspartate is a hydroxycinnamic acid amide compound that can be isolated from Arabidopsis thaliana cell suspension cultures. N-(E-4-Coumaroyl)-aspartate may be involved in metabolic processes related to specific metabolites found in Arabidopsis thaliana cell cultures.

HY-N16838

cis-Oxyresveratrol-4'-O-glucoside	Structural Classification Solanum mammosum L. Phenols Polyphenols Solanaceae Plants Source Classification	Drug Derivative
cis-Oxyresveratrol-4'-O-glucoside (compound 2a) is a β-D-glucoside derivative of oxyresveratrol, whose parent compound possesses potential anti-inflammatory, antioxidant, free radical scavenging, and tyrosinase inhibitory activities, and can be used in anti-inflammatory, antioxidant, and whitening-related research. cis-Oxyresveratrol-4'-O-glucoside is a product obtained by the biotransformation of oxyresveratrol using cell suspension cultures of Solanum mammosum (a plant of the genus Solanum in the Solanaceae family) .

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cell suspension cultures

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