9 Results for "

chemoprevention

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "chemoprevention" in MCE Product Catalog:

10
Benzo[a]pyrene
Benzo[a]pyrene
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10 Cited Publications
Cat. No.: HY-107377
CAS No.: 50-32-8
Purity:  99.97%
Synonyms: 3,4-Benzopyrene
Category:  

Natural Products Malus pumila Mill. Rosaceae Extract Plants Disease Research Fields Cancer

Target:  

Environmental Pollutants Endogenous Metabolite

Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies.
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Lucidenic acid D
Lucidenic acid D
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Cat. No.: HY-107260
CAS No.: 98665-16-8
Purity:  99.78%
Synonyms: Lucidenic acid D2
Category:  

Cardiovascular Disease Triterpenes Terpenoids Polyporaceae Extract Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Disease Research Fields Inflammation/Immunology

Target:  

NO Synthase COX

Lucidenic acid D is a highly oxidized triterpenoid with anti-inflammatory and antiviral activities. Lucidenic acid D attenuates lipopolysaccharide-induced release of proinflammatory cytokines and nitric oxide, reduces the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), and inhibits skin inflammation. Lucidenic acid D suppresses 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced expression of Epstein-Barr virus (EBV) early antigen and maintains the viability of Raji cells. Lucidenic acid D can be used in studies of cancer chemoprevention .
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Benzo[a]pyrene-d12
Benzo[a]pyrene-d12
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Cat. No.: HY-107377S
CAS No.: 63466-71-7
Benzo[a]pyrene-d12 is the deuterium labeled Benzo[a]pyrene . Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies .
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Dihydrorotenone
Dihydrorotenone
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Cat. No.: HY-N4202
CAS No.: 6659-45-6
Category:  

Convolvulaceae Extract Erycibe ferruginea C. Y. Wu Flavonoids Neurological Disease Isoflavanones Plants Disease Research Fields Biological Pesticide Research Agricultural Research

Target:  

Environmental Pollutants Insecticide Apoptosis p38 MAPK

Dihydrorotenone is an insecticide and irreversible inhibitor of mitochondrial complex I. Dihydrorotenone may induce Parkinson's disease. Dihydrorotenone induces apoptosis in human plasma cells by triggering endoplasmic reticulum stress and activating the p38 signaling pathway. The oral LD50 of dihydrorotenone in rats is approximately 2.5 g/kg. Dihydrorotenone exhibits insecticide activity and cytotoxicity to plasma cells. Dihydrorotenone can be used to establish animal models of Parkinson's disease, safety assessment of natural pesticides, and potential cancer chemoprevention studies .
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Benzo[a]pyrene (Standard)
Benzo[a]pyrene (Standard)
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Cat. No.: HY-107377R
CAS No.: 50-32-8
Synonyms: 3,4-Benzopyrene (Standard)
Category:  

Natural Products Malus pumila Mill. Rosaceae Extract Plants

Target:  

Reference Standards Endogenous Metabolite

Benzo[a]pyrene (Standard) is the analytical standard of Benzo[a]pyrene. This product is intended for research and analytical applications. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies.
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4'-Methoxyflavone
4'-Methoxyflavone
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Cat. No.: HY-139054
CAS No.: 4143-74-2
Purity:  99.63%
Category:  

Flavonoids Flavones Endogenous metabolite

Target:  

Apoptosis

4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. 4'-Methoxyflavone can inhibit cycle-dependent kinases leading to cell cycle arrest and regulate cell signaling pathways to influence cell proliferation and apoptosis. 4'-Methoxyflavone can be used in cancer chemoprevention research .
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mCMQ069
mCMQ069
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Cat. No.: HY-162696
CAS No.: 3025257-02-4
Target:  

Parasite

Research Areas:  

Infection

mCMQ069 is an orally active and potent antimalarial. mCMQ069 has potential for a single-dose cure and/or 28-day chemoprevention .
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COX-2-IN-6
COX-2-IN-6
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Cat. No.: HY-115866
CAS No.: 2756347-91-6
Purity:  98.80%
Target:  

COX

Research Areas:  

Cancer

COX-2-IN-6 (compound 10) is an orally active, gut-restricted and selective cyclooxygenase-2 (COX-2) inhibitor for colorectal Chemoprevention of cancer. COX-2-IN-6 selectively targets COX-2 with an IC50 of 0.84 μM and a Ki of 69 nM. COX-2-IN-6 also inhibits COX-2-driven PGE2 synthesis with an IC50 of 0.60 μM .
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Methyl lucidenate D
Methyl lucidenate D
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Cat. No.: HY-N13723
CAS No.: 98665-09-9
Category:  

Triterpenes Terpenoids Polyporaceae Extract Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants

Target:  

EBV

Methyl lucidenate D is a selective inhibitor of Epstein-Barr virus early antigen (EBV-EA) activation with an IC50 of 290 mol ratio/32 pmol TPA. Methyl lucidenate D exerts potential anti-tumor promoting activity by inhibiting TPA-induced EBV-EA activation and maintains major Raji cell survival (70%) at effective concentrations. Methyl lucidenate D can be used in the field of cancer chemoprevention .
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