21 Results for "

cornea

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "cornea" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-P1222
CAS No.: 154947-66-7
Target:  

Bacterial

Research Areas:  

Infection

LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing .
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6
6 Publications Verification
Cat. No.: HY-P1222A
Target:  

Bacterial

Research Areas:  

Infection

LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing .
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6
6 Publications Verification
Cat. No.: HY-P1222B
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

LL-37, human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human acetate could help protect the cornea from infection and modulates wound healing .
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5
5 Cited Publications
Cat. No.: HY-B0577
CAS No.: 130209-82-4
Synonyms: PHXA41
Research Areas:  

Cardiovascular Disease Others

Latanoprost (PHXA41) is a prostaglandin F2α analogue and can be used for glaucoma research. Latanoprost can effectively pass through cornea and be hydrolyzed by esterase to latanoprost acid. latanoprost acid is an F-prostaglandin (FP) receptor agonist, and can effectively reduce intraocular pressure (IOP) by increasing the outflow of aqueous humor through uvea .
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2
2 Cited Publications
Cat. No.: HY-P4846
CAS No.: 292171-04-1
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and acts as a CXCR2 agonist . Ac-Pro-Gly-Pro-OH exerts bactericidal activity by generating hydrogen peroxide, inhibits pulmonary inflammation, and reduces immune cell apoptosis (apoptosis). Ac-Pro-Gly-Pro-OH promotes the production of IFN-γ and inhibits the production of TNF-α and IL-6 in leukocytes. Ac-Pro-Gly-Pro-OH increases the survival rate of mice in sepsis models, enhances the bactericidal activity of neutrophils, acts as a neutrophil chemoattractant, induces neutrophil polarization, and regulates inflammatory and repair processes. Ac-Pro-Gly-Pro-OH induces chronic inflammation and tissue remodeling through sustained action. Ac-Pro-Gly-Pro-OH is released via alkaline hydrolysis of corneal proteins in alkali-injured eyes, thereby driving the early infiltration of neutrophils into the cornea. Ac-Pro-Gly-Pro-OH is applicable to research related to sepsis, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis obliterans syndrome, severe asthma, idiopathic pulmonary fibrosis, and corneal ulcer .
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Cat. No.: HY-B1288
CAS No.: 5987-82-6
Synonyms: Benoxinate hydrochloride
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Oxybuprocaine hydrochloride (Benoxinate hydrochloride) reversibly blocks sodium channels and prevents propagation of painful nerve impulses in the cornea, conjunctiva, and sclera. Oxybuprocaine hydrochloride is used especially in ophthalmology and otolaryngology .
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Cat. No.: HY-P1194
CAS No.: 91224-37-2
Target:  

Neurokinin Receptor

Research Areas:  

Inflammation/Immunology

Spantide I, a substance P analog, is a selective NK1 receptor antagonist, with Ki values of 230 nM and 8150 nM for NK1 and NK2 receptor, respectively. Spantide I provides an approach to reduce type 1 and enhance the type 2 cytokine IL-10 in the infected cornea, leading to a significant reduction in corneal perforation .
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Cat. No.: HY-124404
CAS No.: 82337-46-0
Purity:  ≥99.0%
12(R)-HETE is a CYP-dependent arachidonic acid metabolite that acts as a proinflammatory lipid mediator. 12 (R)-HETE widely exists in various tissues including the eye, skin and liver. In the cornea, 12(R)-HETE is metabolized via pathways such as β-oxidation into the precursor of 12(R)-HETrE. Without direct receptor binding, 12(R)-HETE indirectly activates AHR-mediated target gene transcription, while inhibiting the enzymatic activity of Na+,K+-ATPase and the intracellular calcium elevation induced by TP agonists. 12(R)-HETE also possesses multiple physiological effects such as chemotaxis, proangiogenesis, vasodilation, natriuresis, diuresis and intraocular pressure reduction, and can be widely used in studies related to psoriasis, inflammatory skin diseases and ocular inflammation .
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Cat. No.: HY-155238
CAS No.: 1520073-91-9
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

E2730 is a noncompetitive but selective inhibitor of gamma-aminobutyric acid (GABA) transporter 1 (GAT1) with orally available and antiepileptic activity. E2730-mediated GAT1 inhibition is positively correlated with environmental GABA levels and selectively inhibits GAT1-mediated GABA uptake. E2730 (5-50 mg/kg; po) in rat amygdala ignition model, and in mouse cornea ignition (5-50 mg/kg), drug resistance 6Hz-44mA has demonstrated in vivo efficacy in models of psychomotor epilepsy (5-50 mg/kg), fragile X syndrome (2.5-300 mg/kg), and Dravet syndrome (10 mg/kg, 20 mg/kg) .
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Cat. No.: HY-B1288R
CAS No.: 5987-82-6
Synonyms: Benoxinate hydrochloride (Standard)
Research Areas:  

Neurological Disease

Oxybuprocaine (hydrochloride) (Standard) is the analytical standard of Oxybuprocaine (hydrochloride). This product is intended for research and analytical applications. Oxybuprocaine hydrochloride (Benoxinate hydrochloride) reversibly blocks sodium channels and prevents propagation of painful nerve impulses in the cornea, conjunctiva, and sclera. Oxybuprocaine hydrochloride is used especially in ophthalmology and otolaryngology .
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Cat. No.: HY-P1194A
Target:  

Neurokinin Receptor

Research Areas:  

Inflammation/Immunology

Spantide I TFA, a substance P analog, is a selective NK1 receptor antagonist, with Ki values of 230 nM and 8150 nM for NK1 and NK2 receptor, respectively. Spantide I provides an approach to reduce type 1 and enhance the type 2 cytokine IL-10 in the infected cornea, leading to a significant reduction in corneal perforation .
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Cat. No.: HY-P811030
Synonyms: CDT6; Angiopoietin-related protein 7; Angiopoietin-like factor; Angiopoietin-like protein 7; cornea-derived transcript 6 protein

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P811028
Synonyms: CDT6, UNQ313/PRO356, ANGPTL7, Angiopoietin-related protein 7, Angiopoietin-like factor, Angiopoietin-like protein 7, cornea-derived transcript 6 protein

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7509
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; cornea-Derived Transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75507
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; cornea-Derived Transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:  
Canine
Source:  
HEK293
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Cat. No.: HY-P700852
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; cornea-Derived Transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75508
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; cornea-Derived Transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:  
Canine
Source:  
HEK293
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Cat. No.: HY-P704267
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; cornea-Derived Transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75506
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; cornea-Derived Transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P700955
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL7; Angiopoietin-Like Protein 7; Angiopoietin Like 7; Angiopoietin-Like Factor (CDT6); CDT6; Angiopoietin-Like Factor; AngX; Angiopoietin-Like 7; cornea-Derived Transcript 6 Protein; DJ647M16.1; Angiopoietin-Related Protein 7
Species:  
Human
Source:  
HEK293
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