161 Results for "

expansion

" in MedChemExpress (MCE) Product Catalog:
Products (161)

161 Results for "expansion" in MCE Product Catalog:

43
43 Publications Verification
Cat. No.: HY-N0293
CAS No.: 23180-57-6
Synonyms: Peoniflorin
Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .
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31
31 Cited Publications
Cat. No.: HY-P7077
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-Cell Clonal expansion; TCGF; T-Cell Growth Factor; Interleukin-2; Lymphokine
Species:  
Mouse
Source:  
E. coli
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28
28 Cited Publications
Cat. No.: HY-15689
CAS No.: 1204669-58-8
Purity:  98.47%
Synonyms: INCB 024360
Epacadostat (INCB 024360) is a potent and selective indoleamine 2,3-dioxigenase 1 (IDO1) inhibitor with an IC50 of 71.8 nM . Epacadostat can effectively reduce Trp metabolism, entailing increased activation and maturation of dendritic cells, and enhanced proliferation of effector T cells and natural killer cells (NKs), as well as attenuated Tregs expansion.
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25
25 Cited Publications
Cat. No.: HY-18569
CAS No.: 87-51-4
Synonyms: Indole-3-acetic acid; 3-IAA
3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
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25
25 Cited Publications
Cat. No.: HY-18569A
CAS No.: 6505-45-9
Synonyms: Indole-3-acetic acid sodium; 3-IAA sodium
3-Indoleacetic acid sodium is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
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24
24 Cited Publications
Cat. No.: HY-P7037
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-Cell Clonal expansion; TCGF; T-Cell Growth Factor; Interleukin-2; Lymphokine
Species:  
Human
Source:  
E. coli
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7
7 Cited Publications
Cat. No.: HY-P2260
CAS No.: 1423821-88-8
Target:  

CHIKV Autophagy HIV

Research Areas:  

Infection

Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV) .
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5
5 Cited Publications
Cat. No.: HY-P7037B
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-Cell Clonal expansion; TCGF; T-Cell Growth Factor; Interleukin-2; Lymphokine
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-P70758
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-Cell Clonal expansion; TCGF; T-Cell Growth Factor; Interleukin-2; Lymphokine
Species:  
Human
Source:  
HEK293
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3
3 Cited Publications
Cat. No.: HY-103244
CAS No.: 338404-52-7
Purity:  99.60%
Target:  

Apoptosis

Research Areas:  

Cancer

CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors .
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3
3 Cited Publications
Cat. No.: HY-109086
CAS No.: 1142363-52-7
Purity:  98.80%
Synonyms: JNJ-40346527; JNJ-527
Target:  

c-Fms

Edicotinib (JNJ-40346527) is a potent, selective, brain penetrant and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor with an IC50 of 3.2 nM. Edicotinib exhibits less inhibitory effects on KIT and FLT3 with IC50 values of 20 nM and 190 nM, respectively . Edicotinib limits microglial expansion and attenuates microglial proliferation and neurodegeneration in mice. Edicotinib has the potential for Alzheimer’s disease and rheumatoid arthritis research .
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2
2 Cited Publications
Cat. No.: HY-18569S
CAS No.: 76937-78-5
Synonyms: Indole-3-acetic acid-d5; 3-IAA-d5
3-Indoleacetic acid-d5 (Indole-3-acetic acid-d5) is the deuterated-labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
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2
2 Cited Publications
Cat. No.: HY-100791
CAS No.: 1796596-46-7
Purity:  99.05%
Target:  

CDK

Research Areas:  

Cancer

NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.
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1
1 Cited Publications
Cat. No.: HY-132581
CAS No.: 2170507-65-8
Synonyms: BIIB078; IONIS-C9Rx
Target:  

Ras Others

Research Areas:  

Neurological Disease

Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion .
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1
1 Cited Publications
Cat. No.: HY-132581A
Purity:  90.06%
Synonyms: BIIB078 sodium; IONIS-C9Rx sodium
Target:  

Ras

Research Areas:  

Neurological Disease

Tadnersen sodium, an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion .
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1
1 Cited Publications
Cat. No.: HY-P70718
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-Cell Clonal expansion; TCGF; T-Cell Growth Factor; Interleukin-2; Lymphokine
Species:  
Rat
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7037AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-Cell Clonal expansion; TCGF; T-Cell Growth Factor; Interleukin-2; Lymphokine
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P70646AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T Cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-Cell Clonal expansion; TCGF; T-Cell Growth Factor; Interleukin-2; Lymphokine
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-159649
CAS No.: 2618418-12-3
Research Areas:  

Inflammation/Immunology Cancer

BMS-986408 is an orally active inhibitor of DGKα and DGKζ, with IC50 values of 0.0003 μM and 0.002 μM, respectively. BMS-986408 activates intratumoral T cell responses, enhances the priming and expansion of tumor-reactive T cells in tumor-draining lymph nodes, and functions as an immunostimulant. BMS-986408 can be used in the research of tumors .
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Cat. No.: HY-134669
CAS No.: 1610703-09-7
Purity:  98.30%
Synonyms: N-Cyclopropene-L-Lysine
Research Areas:  

Cancer

CypK (N-Cyclopropene-L-Lysine), a cyclopropene derivative of lysine, is efficiently incorporated into antibodies through genetic-code expansion. CypK is a minimal bioorthogonal handle for the creation of stable therapeutic protein conjugates .
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