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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
glucosedependent insulinotropic polypeptide receptor (GIPR)
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "glucosedependent insulinotropic polypeptide receptor (GIPR)" in MCE Product Catalog:
3
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3
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3
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Cat. No.: HY-164535
CAS No.: 2887445-76-1
Synonyms: AMG 133
Research Areas:
Maridebart cafraglutide (AMG 133) is a long-acting peptide-antibody conjugate that combines GLP-1 receptor agonist with glucose-dependent insulinotropic polypeptide (GIP) receptor antagonism. Maridebart cafraglutide shows antagonist activity against human, cynomolgus monkey and rat GIPR with IC50 values of 46.4 nM, 26.5 nM, 822.3 nM, respectively. Maridebart cafraglutide shows agonist activity against human, cynomolgus monkey, rat and mouse GLP-1R with EC50 values of 24.4 pM, 5.7 pM, 2.4 pM and 123 pM, respectively. Maridebart cafraglutide can be used for the study of obesity and type 2 diabetes .
Cat. No.: HY-P10271
Synonyms: NNC0090-2746; MAR709; RO6811135
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Cat. No.: HY-P11321A
Synonyms: acyl-GIP hydrochloride
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IUB0271 hydrochloride (acyl-GIP hydrochloride) is a glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist with blood-brain barrier permeability. IUB0271 hydrochloride activates the GIPR signaling pathway, inhibits food intake and weight gain, and induces cFos neuron activation in the area postrema. IUB0271 hydrochloride enhances lipid clearance and induces systemic fatty acid oxidation. IUB0271 hydrochloride improves dyslipidemia, reduces atherosclerotic plaque formation and decreases adipocyte volume. IUB0271 hydrochloride can be used in studies related to obesity, dyslipidemia and atherosclerosis .
Cat. No.: HY-P11321
Synonyms: acyl-GIP
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IUB0271 (acyl-GIP) is a glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist with blood-brain barrier permeability. IUB0271 activates the GIPR signaling pathway, inhibits food intake and weight gain, and induces cFos neuron activation in the area postrema. IUB0271 enhances lipid clearance and induces systemic fatty acid oxidation. IUB0271 improves dyslipidemia, reduces atherosclerotic plaque formation and decreases adipocyte volume. IUB0271 can be used in studies related to obesity, dyslipidemia and atherosclerosis .
Cat. No.: HY-P3506CP
CAS No.: 2381089-83-2
Synonyms: LY3437943 (crude)
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Cat. No.: HY-P702285
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-P702800
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Human
Source:
HEK293
Cat. No.: HY-P702801
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P702802
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Rat
Source:
HEK293
Cat. No.: HY-P702803
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Cynomolgus
Source:
P. pastoris
Cat. No.: HY-P703990
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Human
Source:
HEK293
Cat. No.: HY-P703685
Purity: ≥ 95%, as determined by reducing Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-179332
CAS No.: 3059497-30-9
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GIPR antagonist 1 is a GIPR antagonist with an IC50 of 4.8 nM. GIPR antagonist 1 inhibits glucose-dependent insulinotropic polypeptide receptor signaling. GIPR antagonist 1 can be used for the research of type 2 diabetes and obesity .
Cat. No.: HY-P703965
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P703982
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GIPR; GIP-R; Gastric Inhibitory polypeptide receptor; PGQTL2; Glucose-Dependent insulinotropic polypeptide receptor
Species:
Human
Source:
HEK293
Cat. No.: HY-P0276F
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Cat. No.: HY-186050
CAS No.: 3105300-99-7
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GIPR antagonist 2 is a glucose-dependent insulinotropic polypeptide receptor (GIPR) antagonist with an IC50 of 7.2 nM in CHO-K1 cells. GIPR antagonist 2 can be used in research related to diseases such as obesity, type 2 diabetes, non-alcoholic fatty liver disease, and atherosclerosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
